ID A0A0N5DBX9_THECL Unreviewed; 919 AA.
AC A0A0N5DBX9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Myosin motor domain-containing protein {ECO:0000313|WBParaSite:TCLT_0001069801-mRNA-1};
GN ORFNames=TCLT_LOCUS10680 {ECO:0000313|EMBL:VDN08389.1};
OS Thelazia callipaeda (Oriental eyeworm) (Parasitic nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Thelazioidea; Thelaziidae; Thelazia.
OX NCBI_TaxID=103827 {ECO:0000313|Proteomes:UP000046394, ECO:0000313|WBParaSite:TCLT_0001069801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TCLT_0001069801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDN08389.1, ECO:0000313|Proteomes:UP000276776}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; UYYF01005262; VDN08389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N5DBX9; -.
DR STRING; 103827.A0A0N5DBX9; -.
DR WBParaSite; TCLT_0001069801-mRNA-1; TCLT_0001069801-mRNA-1; TCLT_0001069801.
DR OMA; EMMVSKE; -.
DR Proteomes; UP000046394; Unplaced.
DR Proteomes; UP000276776; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140:SF860; DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 5.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50096; IQ; 5.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000276776}.
FT DOMAIN 79..767
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 622..644
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 176..183
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 919 AA; 107287 MW; 6CC89493D1FAAD75 CRC64;
MTAFVGTFGR DQPFPIENYK KGAKVWLKDP NKVWISGELL QDFKFSSKLS ILLEDERVIE
FALKESEGLP FLKNPDILLG RDDLTTLSYL HEPAVLNHLN FRFVKREAIY TYCGIVLVAI
NPYANCSQLY GEDVIQIYRG VGKQVRELDP HIYAVAEEAY FDLHELEKNQ SVIVSGESGA
GKTVSAKFVM RYLTFVASSP LNKPYGCVPT DVGIEDRVLA SNPIMEAIGN AKTIRNDNSS
RFGKYIQINF DERFSVAGAE MKTYLLEKNR VVYQAENERN YHIFYQICAS KSHFLLEELN
LGVNDWHAYS YTAQGKSGQI ENIDDGKDFL ETLTAMNLLH ISTDIQKSVF RVFAGLLLFG
NIKFIDGREE YAEIDQNTLP TIYYLCKKIY EVREEDLCNW LVSRRINAGS ESVQKPLTVT
QAVICRDALV KMLYASIFTW IVKRINEALG DGSSNNTVMK TQRFIGVLDI YGFETFEVNS
FEQFCINYAN EKLQQQFCQH VFKLEQSEYE REEIDWIRID FYDNQSCIDL IEGRPGIIDY
LDEQCKMGQG TDRDWLERLR SCQSLKKMQH FQLSKIKNPS FIIKHFAADV VYNVDGFLEK
NMDTVSEQLV NVIKNSKFRD SLRELMAVLG STRPHYVRCI KPNDDKLPFT FEPKRAIQQL
RACGVLETVR ISAAGYPSRW NYDDFARRYR VLYPQKKLWR ENPKSFAEHA CSKYLAVCFY
SSYNQTLPFI RCGLQNTLMF QSEMYALGKT KVFFRTGQVA LLERILHEKL TSSAVLIQKT
WKGLSARKKY QFIKESIAKI QIYCLAFVMY RRMKYLQMHR AIICLQTAFR SYSARRRYNL
LRSTVIMIQT HYRASLIRQK VKKLRYEQKA ITIQKYYRGW RVRREQSERK QKVIMIQCQV
RQWLARRRLR ELKVSPFLH
//
