ID A0A0N6ZXZ9_9MICO Unreviewed; 1163 AA.
AC A0A0N6ZXZ9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=NI26_05910 {ECO:0000313|EMBL:AIV39857.1};
OS Curtobacterium sp. MR_MD2014.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Curtobacterium.
OX NCBI_TaxID=1561023 {ECO:0000313|EMBL:AIV39857.1, ECO:0000313|Proteomes:UP000069933};
RN [1] {ECO:0000313|Proteomes:UP000069933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR_MD2014 {ECO:0000313|Proteomes:UP000069933};
RA Mariita R.M., Bhatgnagar S., Hanselmann K., Hossain M.J., Dawson S.C.,
RA Korlach J., Boitano M., Liles M.R., Moss A.G., Leadbetter J.R.,
RA Newman D.K.;
RT "Isolation and characterization of species affiliated with family
RT Actinomycetaceae.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AIV39857.1, ECO:0000313|Proteomes:UP000069933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR_MD2014 {ECO:0000313|EMBL:AIV39857.1,
RC ECO:0000313|Proteomes:UP000069933};
RX PubMed=26722011;
RA Mariita R.M., Bhatnagar S., Hanselmann K., Hossain M.J., Korlach J.,
RA Boitano M., Roberts R.J., Liles M.R., Moss A.G., Leadbetter J.R.,
RA Newman D.K., Dawson S.C.;
RT "Complete Genome Sequence of Curtobacterium sp. Strain MR_MD2014, Isolated
RT from Topsoil in Woods Hole, Massachusetts.";
RL Genome Announc. 3:0-0(2015).
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DR EMBL; CP009755; AIV39857.1; -; Genomic_DNA.
DR RefSeq; WP_066653558.1; NZ_CP009755.1.
DR AlphaFoldDB; A0A0N6ZXZ9; -.
DR STRING; 1561023.NI26_05910; -.
DR KEGG; cum:NI26_05910; -.
DR PATRIC; fig|1561023.3.peg.1229; -.
DR OrthoDB; 9757917at2; -.
DR Proteomes; UP000069933; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17934; DEXXQc_Upf1-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR038720; YprB_RNase_H-like_dom.
DR NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF13482; RNase_H_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000069933}.
FT DOMAIN 11..225
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
FT DOMAIN 327..514
FT /note="YprB ribonuclease H-like"
FT /evidence="ECO:0000259|Pfam:PF13482"
FT DOMAIN 965..1133
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 286..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1163 AA; 126999 MW; BA64D64EC52E1397 CRC64;
MQITSDSRVL LSPSDLSTWA TCEWAFLRRL DAKLGRGGPL PDEHDDMLER TARLGDQHEL
DYLDILKQTR DVVEFDRPAP PDYAAAAQRA INAFQTGADV LYQPTFHEPP TPARPGFIGF
ADFILRNAEG AYEVYDTKLA RHAKISALLQ LAAYAEQMQA HGIPTGEQVH LVLGDRTTTT
HDLADIAPVY RTQRAELKRV IAERMQEHEE LQWGDARYSS CGRCTICQTQ VQQHRDLVLV
AGMRLDQRTK LIRQGVRTID DLADRTAAVP GMSRSTQERL VRQARLQTET EAEQRDSGAK
TGPTKPRFEL HDPRALDAIP EPDPGDVFFD FEGDPLHTED GVHWGLDYLF GLVDDRADFT
AFWAHTIRDE RQALIDFLAF VKERRAQHPG MHVYHYAAYE RTHLLSLAAR HGVGEDDVDD
LLRAGVLVDL YPIVRKALVV GSHSYSIKKL EPLYMGEDFR LSDVTNAADS ITAYVEAIEE
LRSGDPATGQ RMLDQVADYN AYDCRSTLRL RDWLLSLRLP RTEPATEETE LLPPIPVERE
PNPVYTALAA QIADVDPLDR DADQTALALA AAAIDYHRRE AKTFWQDHFD RLRNPVDDWA
DTRDVLVVER ASVERDWDTL PRARSQSREI RLSGTLAPGS RIRPGGTPHL VYDDPLPPSV
TAPAPGSKGA SARAVVLDAA DNGDAFEVLV KESLAVGGGE PHHDFPVALA PAAPPRAKPQ
PEAIAEWGQE VLDALPEMLP DPALDLLRRV PPRGALAPVA GDDTVSAVVT TLLGLDRSYL
AIQGPPGTGK TYVGSNVVAR LVREHGWRVG VVGQSHATSE NFLSSVVRAG VSADRVVKVP
KSGATEDELE AVAWTPVKNN AAVSAFLSSC AETGTGGVVG GTAWTFANEG TIPRRLLDLL
VVDEAGQFSL APTIASSIAA QRLLLLGDPQ QLPQVSQGSH PEPVDQSALG WLADGEHVLP
PEFGYFLAHT RRMEPALTAS VSGLSYDGQL TSIVSGRHLD DLDPGVHPVP VVHSGNTTSS
EEEAARVVEL AQSLIGRRWV DGEVSRPLTD EDVIVVAPYN AQGALIREAL DRAGLRGTQV
GTVDMFQGRE AVVSITSLAA SSAADIPRGL DFLLMPNRLN VALSRAQWAA YLVYSPALTT
GLPSSISGLS LLSRFIELVE PPH
//
