UniProt: A0A0N7IG94

Database: UniProt
Entry: A0A0N7IG94_9BACE

LinkDB:  A0A0N7IG94_9BACE 
Original site:  A0A0N7IG94_9BACE

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Ontology (1)   
   GO (1)   
Gene (2)   
   KEGG GENES (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   EMBL (7)   
Protein domain (1)   
   Pfam (1)   
Literature (2)   
   PubMed (2)   
All databases (14)   

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ID   A0A0N7IG94_9BACE        Unreviewed;       415 AA.
AC   A0A0N7IG94;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=HlyD family efflux transporter periplasmic adaptor subunit {ECO:0000313|EMBL:KAA5405173.1};
DE   SubName: Full=Macrolide transporter subunit MacA {ECO:0000313|EMBL:ALJ62371.1};
GN   ORFNames=BcellWH2_05163 {ECO:0000313|EMBL:ALJ62371.1}, DWW88_24290
GN   {ECO:0000313|EMBL:RGU20690.1}, DWX97_22845
GN   {ECO:0000313|EMBL:RGS33008.1}, F2Y70_11120
GN   {ECO:0000313|EMBL:KAA5426024.1}, F2Y81_11835
GN   {ECO:0000313|EMBL:KAA5418132.1}, F2Y86_19800
GN   {ECO:0000313|EMBL:KAA5405173.1}, F2Y87_19190
GN   {ECO:0000313|EMBL:KAA5416243.1};
OS   Bacteroides cellulosilyticus.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=246787 {ECO:0000313|EMBL:ALJ62371.1, ECO:0000313|Proteomes:UP000061809};
RN   [1] {ECO:0000313|EMBL:ALJ62371.1, ECO:0000313|Proteomes:UP000061809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH2 {ECO:0000313|EMBL:ALJ62371.1,
RC   ECO:0000313|Proteomes:UP000061809};
RX   PubMed=26430127;
RA   Wu M., McNulty N.P., Rodionov D.A., Khoroshkin M.S., Griffin N.W.,
RA   Cheng J., Latreille P., Kerstetter R.A., Terrapon N., Henrissat B.,
RA   Osterman A.L., Gordon J.I.;
RT   "Genetic determinants of in vivo fitness and diet responsiveness in
RT   multiple human gut Bacteroides.";
RL   Science 350:AAC5992-AAC5992(2015).
RN   [2] {ECO:0000313|Proteomes:UP000283341, ECO:0000313|Proteomes:UP000285677}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF17-25 {ECO:0000313|EMBL:RGU20690.1,
RC   ECO:0000313|Proteomes:UP000285677}, and AF22-3AC
RC   {ECO:0000313|EMBL:RGS33008.1, ECO:0000313|Proteomes:UP000283341};
RA   Zou Y., Xue W., Luo G.;
RT   "A genome reference for cultivated species of the human gut microbiota.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Proteomes:UP000325055, ECO:0000313|Proteomes:UP000448877}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BIOML-A3 {ECO:0000313|EMBL:KAA5426024.1,
RC   ECO:0000313|Proteomes:UP000475645}, BIOML-A6
RC   {ECO:0000313|EMBL:KAA5418132.1, ECO:0000313|Proteomes:UP000448877},
RC   BIOML-A7 {ECO:0000313|EMBL:KAA5405173.1,
RC   ECO:0000313|Proteomes:UP000325055}, and BIOML-A8
RC   {ECO:0000313|EMBL:KAA5416243.1, ECO:0000313|Proteomes:UP000482653};
RX   PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA   Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA   Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA   Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA   Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA   Xavier R.J., Alm E.J.;
RT   "A library of human gut bacterial isolates paired with longitudinal
RT   multiomics data enables mechanistic microbiome research.";
RL   Nat. Med. 25:1442-1452(2019).
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DR   EMBL; CP012801; ALJ62371.1; -; Genomic_DNA.
DR   EMBL; VVYW01000019; KAA5405173.1; -; Genomic_DNA.
DR   EMBL; VVYX01000025; KAA5416243.1; -; Genomic_DNA.
DR   EMBL; VVYV01000018; KAA5418132.1; -; Genomic_DNA.
DR   EMBL; VVYT01000028; KAA5426024.1; -; Genomic_DNA.
DR   EMBL; QRVJ01000032; RGS33008.1; -; Genomic_DNA.
DR   EMBL; QRXS01000020; RGU20690.1; -; Genomic_DNA.
DR   RefSeq; WP_007209988.1; NZ_VVYX01000025.1.
DR   AlphaFoldDB; A0A0N7IG94; -.
DR   STRING; 246787.BcellWH2_05163; -.
DR   GeneID; 66308870; -.
DR   KEGG; bcel:BcellWH2_05163; -.
DR   PATRIC; fig|246787.4.peg.5333; -.
DR   eggNOG; COG0845; Bacteria.
DR   Proteomes; UP000061809; Chromosome.
DR   Proteomes; UP000283341; Unassembled WGS sequence.
DR   Proteomes; UP000285677; Unassembled WGS sequence.
DR   Proteomes; UP000325055; Unassembled WGS sequence.
DR   Proteomes; UP000448877; Unassembled WGS sequence.
DR   Proteomes; UP000475645; Unassembled WGS sequence.
DR   Proteomes; UP000482653; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.420.20; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   Pfam; PF13437; HlyD_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          176..210
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   415 AA;  46543 MW;  4EE10C4F9F20AB0E CRC64;
     MDREIPKEVR NKERNKKIIR YGGIGVASVI VISVLISFMR TGVKTKDLVF STVDKGTIEV
     SVSASGKVVP AFEEIINSPI NTRIVEIYKK GGDSVDIGTP ILKLDLQSVE TDYKKLLDEE
     QMRSYKLNQL RVNNQTKLND LAMKIKVSAM QLNRKKVELR NEQYLDSLGS GTTDKVRQAE
     LSYNVAQLEY EQLEQQYDNE KEVLAAEYKV QELDFSIFRK GLAEMKRTLD DAQIRSPRKA
     ILTYINNQIG AQVSQGSQLA VISDLSHFKV EGEIADTYGD RVAAGGKAIV KIGSEKLEGT
     VSSVTPLSKN GVISFTVQLN EDNNRRLRSG LKTDVYVMNA VKEDVMRIAN ASYYVGRGEY
     ELFVRNSDKE IVKRKVQLGD SNFEFVEVAS GLQPGDQVVV SDMSNYKNKN KLKLN
//

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