ID A0A0N7K008_9PSEU Unreviewed; 496 AA.
AC A0A0N7K008;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=AMP-dependent synthetase {ECO:0000313|EMBL:ALL83740.1};
GN ORFNames=AD017_25700 {ECO:0000313|EMBL:ALL83740.1};
OS Pseudonocardia sp. EC080619-01.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1096856 {ECO:0000313|EMBL:ALL83740.1, ECO:0000313|Proteomes:UP000066228};
RN [1] {ECO:0000313|EMBL:ALL83740.1, ECO:0000313|Proteomes:UP000066228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC080619-01 {ECO:0000313|EMBL:ALL83740.1,
RC ECO:0000313|Proteomes:UP000066228};
RX PubMed=26535611; DOI=10.1021/jacs.5b09794;
RA Van Arnam E.B., Sit C.S.;
RT "A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense.";
RL J. Am. Chem. Soc. 137:14272-14274(2015).
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DR EMBL; CP012184; ALL83740.1; -; Genomic_DNA.
DR RefSeq; WP_060575819.1; NZ_CP012184.1.
DR AlphaFoldDB; A0A0N7K008; -.
DR STRING; 1096856.AD017_25700; -.
DR KEGG; pecq:AD017_25700; -.
DR PATRIC; fig|1096856.3.peg.5421; -.
DR OrthoDB; 3172305at2; -.
DR Proteomes; UP000066228; Chromosome.
DR CDD; cd17631; FACL_FadD13-like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000066228}.
FT DOMAIN 12..360
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 410..485
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 496 AA; 51930 MW; F8B3055E00030411 CRC64;
MRDDGLGSWP ARRARMTPGR TALVHGDRHD TYADLARRTA ALAAGLRGLG VRRGDRVGYL
GPNHPAYLET LFATASLGAV FVPVNARLAA PELAFVLDDA GVSVLVHTPA AGALVDAAAA
RTLRERLVVG GSYDALAGAA AEPVDEPVGP DDPCLIMYTS GSTGRPKGAV LSHGNLTWNC
VNVLVESDLS GDEVALVAAP LFHTAALGMT CLPTLLKGGT CVLMEAFDPT AALELVARHR
VTLLFGVPAM YDALAARPEW ADTDLSSVRT LLCGGSPVPA ATARRWLERG LAFVQGYGMT
ETAPGVLVLD PASARTKAGT AGVPSFFTDV RIAGPSGEPV APGERGEILV RGPNVMLGYW
NRPDATDEAL AGGWMHSGDV ATADADGYVT VVDRIKDMII SGGENVYPAE IESALYEHPS
VELCAVVGTP DARWGEVPRA VVVLRAGAAA DADGIRAHLR DRLAGYKVPR HVDFADDLPR
TGSGKVLKAA LRERYG
//
