ID A0A0N7L9S4_9BASI Unreviewed; 3176 AA.
AC A0A0N7L9S4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Dynein heavy chain cytosolic {ECO:0000313|EMBL:CEH14594.1};
OS Ceraceosorus bombacis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Exobasidiomycetes; Ceraceosorales; Ceraceosoraceae; Ceraceosorus.
OX NCBI_TaxID=401625 {ECO:0000313|EMBL:CEH14594.1, ECO:0000313|Proteomes:UP000054845};
RN [1] {ECO:0000313|EMBL:CEH14594.1, ECO:0000313|Proteomes:UP000054845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Magalhaes I.L.F., Oliveira U., Santos F.R., Vidigal T.H.D.A.,
RA Brescovit A.D., Santos A.J.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CCYA01000243; CEH14594.1; -; Genomic_DNA.
DR STRING; 401625.A0A0N7L9S4; -.
DR OrthoDB; 312195at2759; -.
DR Proteomes; UP000054845; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd00009; AAA; 2.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46532:SF4; DYNEIN HEAVY CHAIN 8, AXONEMAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46532; MALE FERTILITY FACTOR KL5; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054845}.
FT DOMAIN 2005..2138
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2292..2486
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2669..2824
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 3012..3173
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 164..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1022..1054
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2469..2489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1054
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3176 AA; 355757 MW; 742B7BB51DFDD963 CRC64;
MAAADGGLPP SASIMSLNSN ANGAAGSRAG ISRFPIALIR AYLELLLPVV MAATPAALEE
SLFSSSLGDV DEDAKGDGWH SVAFAFATDP STMTVYIDKV RRDTSGSGTD GLFEYRLDTH
PTYSPRHVSS IALIKRAGAL DPALPLQQQV HVLSLFGPAS EADRHASGEG IAAAPELGRE
DGRGGEEEGI TINIRESPYE ALHSVVHHVM APWFDAYVSS KEDDSKTSAA KTAKPKSKDA
DARIGVPMAK RKFAELELSL LHLQQNVEIP EVYLSCHPQV RATVERCQAA KSKATVEEVR
PSSLLQDSTF LNQLQSDVNN WVKEVQLVTR LDRDVSSGTA SQEINFWLSM ERAQDHIEQQ
LRSEPITLTL DILKHAKRFH ATVSFLADTG LKDCTEKVQA YNILMKEFPL DSLLSATDFD
KCIDAVQAVF NHLNKKMRVS PYPVKRALPL VEAISRDVND AVLKILGAQR VMYQDFSRFC
DTMQGAGDVF ATWDDVMREF VNIAREVTRK RSEKFMPIKI NPAHAKLRER LNYLSAFRKT
HEQLRVMVTS GRGIALAASG SQTGLNTSGI ARTQASAHAF SGIQMADEIT DAFDVVKVVD
VLDVTDEGTA IWSAAESAYN ERVARVENGL IARLRDLLGQ AKNAREMLRV LSQFNTLFVR
PKVRGAVQEY QQQLLNSVKS DIAGLHDKFK AQYRPSEANH MSQLRDIPEI AGAIIWARQI
ERQLMVYMKR VEDVLGKGWE LYAEGQKLRS ESETFSRKLD TRPLFDGWLH DINRRDMTIS
GRLFEVSRNR ATGQYSLGVN FDPQVIALFK EVRHLSWLGF QIPHLINNLA RDAKRVYPYA
VSLMETVRTY NQTCAQVREH PRIACLLART QTDVHNLITS GTTLRWEHFA NAYESHRAIA
AYLPASSTAG DGLRDNKQVS YVRAFASAVS VFQDQTNALI NMNGETSILV DELASCTYTR
SAFAERLAKI QKTIDRLNLD GYPNLDDWVA ELDARIEQVL MERLRLISIA WCEEFARSEE
TREGGSAGAA HRENGAPGGR HRRRDVKETR LSPAEKAALE RDHVELSPVT HEIRIRNQII
YLDPPIEHAR ASWFTQLHDV LGVACGLRRV QSARYEMGVQ MQKLARDVTT ADVTYAGLLT
RFEDTTLSRP FALIEAKVQE VGRYVAKWLR FQNLWDLEAE HVYATLGDSL ARWQQLLAGI
RKTRATFDTS DTQRSFGMAV IDYEQVQSKV NAKYDAWQRD VLNRFGTKLA AEMRETYAAI
RKARYDLEQH SIESSSTAQT VTFITFVTDL KRQTKKWSPQ MSIFATGQKT LERQRYMFSQ
DWLYADQVEG EWSAFNEILA RKNSSIQEQL AGLQMKIIAE DKIVSDKIAV LVTEWEQQKP
IEGTLKADTA LNTISLFEGR VARLCDDRDL VIRAKEALDL EHTPDDRVEP VQEELRDLKA
VWTALSGTWS QLSELRDSSW NNVQPRKLRQ QLDGLLTQTK DMPSRMRQYA AFEYVQNILR
DLLKSNALIS ELKSEAMRER HWRALFKQLQ VSTPYSPTSM TLGIVWDLGL KRHEQAIKAV
IMQAQGEMAL EEFLKEVRER WTSYDLDLVN YQNRCRLVRG WDQLFQSAGD HLSALKSMAN
SPHHKVFEEE AALWESRLSQ VSALFELLRD VQRRWVDCGG IFSGPEMRHI LPVETSRFQV
VDTEFLTITK RINKSPYVLD VINIPSINQS LDRLHDLLDK IQRALGAFLE KQRNVFPRFY
FLGDEDLLSL LGSSKDVMRV GTYIAKMWQG VASVIFSDDS SLIGVRSPQD EYVELARSVP
TAGIAVHEWL QGLETELRKS VAFASEAALA NLAMFFTPSS FEAEKLVDWI ERHIGQTTIL
VLGIQWTKLV EHSLQQGKDG LSAVLNLVES ALDALADSVV QDLPALKRKK IENLLVELVH
ERDVLRELIS HGTKTSDDWA WQSQMRYYSE TSTGTGNAPS ARIEMADASF SYGFNYTGVP
DPMVITPLTT KAFGVFTQAL KQSLAGRSEG PAGTGKTETV SLLGRRLGRE VIVTCCGEEF
DAKSISRGLL GCARVGSWAA FDEINRLSPN VLSSISEDIL SWQSARRQGG GAMLSGQSVE
LTPGAAVFIT LNPTYIGRAT LPRSLTRLFR TVVMAQPDRQ QIIQVLLYAV GFRSAELLAR
KLDPFFHLLE STLSKRSHYD LNSLRSIKAT LAAAGQVKRA QGAHEASGQT VDVVEQSLAV
SAVMGVIVPK LVGEDVALLG ALLDDVFPGI QYQPPALDEL RKHISDVCLE RHLVCDGVWL
DKIIQLYEIQ RISHGVMLVG PSGTGKSVAW SVLLEALHRL EGIDGVSYVM DPKAVSKDGL
YGTLDVTTRE WTDGLFTNVL RRIVDNVRGE SAKRHWIVFD GDVDPVWVEN LNSVLDDNKL
LTLPNGERID LPSNVRVMFE VEHLRFATPA TVSRCGMIWF SEESVTPAML YNNYFGHLRA
RPLGAADDDD LAPSTARRDV ASGSGDSPAS TELVTQRIVA DAIETFFAPQ SLIDTALARA
EDFFHIMPFT ASRALTTLFS LINKTVRNVF DYNQQHPDFP LAPAQIEAYA TKRLVVSVVW
SFTGDAKLHV RAEMGEFLAS QTGVDMPPLD NGASLIDFDV QVATAEWFEW TTRVPTIEIE
THAVASADVV IPTMDTVRHE EVLYSWLSEH KPLMLCGPPG SGKTMTLFAA LRKLPDQEVV
GLNFSSATTP ELILKTFDQH CEYRKTPNGV ILAPKQIGRW IVLFCDEINL PATDQYGTQR
VISFLRQLVE RGGFWRTSDL AWVTLERIQF VGACNPPTDA GRVPLSQRFL RHAPLVMVDY
PGEVSLNQIY GTFNRALLKL APNLRGYAEA LTSAMVDFYL ASQSHFTPDM QAHYVYSPRE
LSRWVRGLYE YLKPVDDTIN VEGLVRIWAH EGLRLFRDRL VGEDEKEWTD SQLDAVALAR
FPTVDQNLAL ARPIIYSNWL TRNTSSVALP DLRAHTVARL AQYSEEELET RLVLHDSVMA
LATSVDRVLR QRQGHLLLIG SSGSGRTTVT RFVAWLVGLS VFTISPSRRY GMADFDEDLR
GILRRAGTQG EKLCFIIDES QVRDPAFLER MNTLLANAEI PGLFEGDEYS ALMTACKEGS
QRDGLMLDSP DELYSWFSSE ISKNLHVVFT FNPEQGVGSR AATSPALFNR AVLIFL
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