ID A0A0N7M070_9RHOB Unreviewed; 879 AA.
AC A0A0N7M070;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|ARBA:ARBA00021982, ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096,
GN ECO:0000313|EMBL:CUH79641.1};
GN ORFNames=TRM7557_02499 {ECO:0000313|EMBL:CUH79641.1};
OS Tritonibacter multivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Tritonibacter.
OX NCBI_TaxID=928856 {ECO:0000313|EMBL:CUH79641.1, ECO:0000313|Proteomes:UP000052022};
RN [1] {ECO:0000313|EMBL:CUH79641.1, ECO:0000313|Proteomes:UP000052022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7557 {ECO:0000313|EMBL:CUH79641.1,
RC ECO:0000313|Proteomes:UP000052022};
RG Swine Surveillance;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|ARBA:ARBA00024647,
CC ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
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DR EMBL; CYSD01000037; CUH79641.1; -; Genomic_DNA.
DR RefSeq; WP_058290521.1; NZ_JAQIPA010000006.1.
DR AlphaFoldDB; A0A0N7M070; -.
DR STRING; 928856.SAMN04488049_101219; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000052022; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 6.10.140.430; -; 1.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000052022}.
FT DOMAIN 703..719
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 629..636
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 879 AA; 95280 MW; C0D82BE674AC7581 CRC64;
MTVTPMMAQY LDIKAQYPDA LLFYRMGDFY EMFFEDAVNA AEALDIALTK RGKHDGNDIP
MCGVPVHAAE GYLLTLIRKG FRVAVGEQLE SPAEAKKRGS KSVVKRDVVR LVTPGTLTED
SLLEARRHNF LVAYAELRDQ AALAWADIST GAFHVMPLAR VRLSPELARL APSELIVADG
PAYDLTRPLA DEYHIPLTPL GKASFDSTAA EKRICALFNV GALDGFGTFT RAEVSAMGAL
VDYLEITQKG KLPLLQPPLQ EAEDRTVQID AATRRNLEIT RSLSGGRAGS LLAVVDRTVT
PGGARLLEQR LSSPSRSLDV IAARLEGLDA MVSDHTLCSA LRDDLRKTPD LDRALSRLAL
ERGGPRDLAA IRNALTQGEA IRTGVAGFEL PHLLTDAVAK LGGFDALLDL LDASLIAEPP
LMARDGGFIA EGYDAELDEA RTLRDEGRSV IAGLQKQYAE QTGITSLKIK HNNVLGYFIE
TTATHSEKML SAPLSETFIH RQTTANQVRF TTVELSELET KILNAGNLAL EIEKRLYQSL
STAILDMAAR LNQAARGFAE LDLITALADL ARAENWSRPR VDTSRTFHVE GGRHPVVEQA
LRQQGGEAFV ANDCDLSAQD GAAVWLLTGP NMAGKSTFLR QNALIAILAQ MGSYVPAEVA
HIGMVSQVFS RVGASDDLAR GRSTFMVEMV ETAAILNQAD NRAMVILDEI GRGTATYDGL
SIAWATLEHL HEVNQSRALF ATHYHELTQL AAKLDGVENA TVAVKEWEGE VIFLHEVRKG
AADRSYGVQV AQLAGLPTAV VERARDVLDM LEQGARDHGA AKIQIDDLPL FAASPAPQPR
APAGPSPLES LLAEIHPDDL SPREALDALY QLKDAAKAQ
//
