ID A0A0N7M8D2_9RHOB Unreviewed; 595 AA.
AC A0A0N7M8D2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Peptidoglycan synthase FtsI {ECO:0000313|EMBL:CUJ86374.1};
DE EC=2.4.1.129 {ECO:0000313|EMBL:CUJ86374.1};
GN Name=ftsI {ECO:0000313|EMBL:CUJ86374.1};
GN ORFNames=RUE5091_00459 {ECO:0000313|EMBL:CUJ86374.1};
OS Ruegeria denitrificans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Ruegeria.
OX NCBI_TaxID=1715692 {ECO:0000313|EMBL:CUJ86374.1, ECO:0000313|Proteomes:UP000051260};
RN [1] {ECO:0000313|EMBL:CUJ86374.1, ECO:0000313|Proteomes:UP000051260}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5091 {ECO:0000313|EMBL:CUJ86374.1,
RC ECO:0000313|Proteomes:UP000051260};
RG Swine Surveillance;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CYUD01000001; CUJ86374.1; -; Genomic_DNA.
DR RefSeq; WP_058280223.1; NZ_CYUD01000001.1.
DR AlphaFoldDB; A0A0N7M8D2; -.
DR STRING; 1715692.RUE5091_00459; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000051260; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000313|EMBL:CUJ86374.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CUJ86374.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 89..223
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 261..555
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 277..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 595 AA; 64234 MW; 13EC4F5E825FCACA CRC64;
MTRTPLRPLA RVLDARARGE NPKAIERENI RQRHENMKDR ARARAEGRLL VLGLFFFCAF
SVVGVRMGML ATSEAQEPLA SAPGAAIAMQ RANIVDREGR ILATNLDTYS VYAQPPAMID
PNAAADQLVA IFPDLDKERL VKDFTGTRKF LWIKKRISPE QKQAVHDIGD PGILFGPREM
RLYPNGRLAA HILGGSGFGR EGVSAAEVIG VAGVEKQFDD YLRDPANGNK PLQLSLDLTI
QAAVEQVLYG GMKIMNAKGA SAVLMNAHTG EVISAASLPS FDPNDRPRPP TSGFDPSDSP
LFNRYVQGVY ELGSVFKIFT AAQAVQLGLV NSETIIDTSG PMRIGRFPIG EFNGKNYGKI
SVADVIVHSS NRGTGRLALQ IGARRQQDFL EALGMFEPTP FEIVEAAGGE PLKPKKWGEL
STVTISYGHG LSTSPMHLAA GYAAIANGGH YVSPTILRKN GAQYGPRVMS ESAAKQAQNM
LRRVVTDGTA SFGDVAGYDV AGKTGTADKP KPRGGYYDDK VIATFATFFP AYDPKYVLIV
TLDEPSIVAY GEKRRTAGWT AVPVAAELIG RIAPLLGLRP RLEPEARAAI TLTSN
//
