ID   A0A0N7MBL2_9RHOB        Unreviewed;       630 AA.
AC   A0A0N7MBL2;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Acetyl-coenzyme A synthetase {ECO:0000313|EMBL:CUK25720.1};
DE            EC=6.2.1.1 {ECO:0000313|EMBL:CUK25720.1};
GN   Name=acsA_3 {ECO:0000313|EMBL:CUK25720.1};
GN   ORFNames=TA5114_01524 {ECO:0000313|EMBL:CUK25720.1};
OS   Cognatishimia activa.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Cognatishimia.
OX   NCBI_TaxID=1715691 {ECO:0000313|EMBL:CUK25720.1, ECO:0000313|Proteomes:UP000051184};
RN   [1] {ECO:0000313|Proteomes:UP000051184}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 5114 {ECO:0000313|Proteomes:UP000051184};
RA   Rodrigo-Torres Lidia, Arahal R.David.;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000256|ARBA:ARBA00006432}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CYUE01000013; CUK25720.1; -; Genomic_DNA.
DR   RefSeq; WP_058314677.1; NZ_CYUE01000013.1.
DR   AlphaFoldDB; A0A0N7MBL2; -.
DR   STRING; 1715691.TA5113_02273; -.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000051184; Unassembled WGS sequence.
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR   CDD; cd05967; PrpE; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR   PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW   Ligase {ECO:0000313|EMBL:CUK25720.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051184}.
FT   DOMAIN          3..57
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          68..444
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          510..588
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   630 AA;  68238 MW;  C8C198B0E9DF8186 CRC64;
     MGYQTIYNAW KADPEGFWLN AAEAIDWVEA PQQALTDKGD GLYEWFADTK VNTCWNAVDR
     HVEAGRGAQA AIIYDSPVTD TKETITYADL KTRVANLAGA LRAQGVEKGD RVIIYMPMVP
     QALEAMLACG RIGAIHSVVF GGFAANELAV RIDDATPKAI IAASCGIEPG RIVEYKPLLD
     AAIEASTHKP ELCVILQREQ HRADMIDGRD VDYYGCQDGV EPADCLPVEG NHPSYILYTS
     GTTGQPKGVI RHTAGQLVAL NWTMQAIYNI KPGEVFWAAS DVGWVVGHSY ICYAPLIHGN
     TTIVFEGKPV GTPDAGTFWR VISEHNVTSF FTAPTALRAV KREDPEGTMV KDYDMSCLGQ
     VYLAGERADP DTLEWAQHHL KVPVIDHWWQ TETGWAIAAN PLGVEELPIK LGSPAKAMPG
     YQVDILGDDG HPVADGELGA IAVKLPLPPG TLPTLWNAEA RFKSSYLEAF PGYYETGDAG
     MKDEDGYLYI MARTDDVINV AGHRLSTGGM EEVLAAHKDV AECAVIGVSD SLKGQMPVGF
     LCLNAGCDRA PEDVIKEVVA DVRNQIGPVA AFKKAVVVDR LPKTRSGKIL RGTMVSIADG
     KEWKMPATID DPAILDEIGE ALKTIGYAQT
//