ID A0A0N8CPN8_9CRUS Unreviewed; 650 AA.
AC A0A0N8CPN8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Putative Integrin alpha-ps {ECO:0000313|EMBL:KZS18875.1};
DE SubName: Full=Zinc carboxypeptidase {ECO:0000313|EMBL:JAL92571.1};
GN ORFNames=APZ42_015468 {ECO:0000313|EMBL:KZS18875.1};
OS Daphnia magna.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=35525 {ECO:0000313|EMBL:JAL92571.1};
RN [1] {ECO:0000313|EMBL:JAL92571.1}
RP NUCLEOTIDE SEQUENCE.
RA Gilbert D., Podicheti R., Orsini L., Colbourne J., Pfrender M.;
RT "Daphnia magna gene sets from two clonal populations assembled and
RT annotated with EvidentialGene.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAL92571.1}
RP NUCLEOTIDE SEQUENCE.
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KZS18875.1, ECO:0000313|Proteomes:UP000076858}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xinb3 {ECO:0000313|EMBL:KZS18875.1,
RC ECO:0000313|Proteomes:UP000076858};
RC TISSUE=Complete organism {ECO:0000313|EMBL:KZS18875.1};
RA Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
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DR EMBL; GDIP01111143; JAL92571.1; -; Transcribed_RNA.
DR EMBL; LRGB01000512; KZS18875.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0N8CPN8; -.
DR STRING; 35525.A0A0N8CPN8; -.
DR Proteomes; UP000076858; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0007157; P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; IEA:UniProt.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF133; INTEGRIN ALPHA-PS2; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF00357; Integrin_alpha; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 4.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 1.
DR PROSITE; PS51470; FG_GAP; 3.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:JAL92571.1};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000313|EMBL:JAL92571.1};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Protease {ECO:0000313|EMBL:JAL92571.1};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000076858};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU003762};
KW Transmembrane {ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|RuleBase:RU003762}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT CHAIN 27..650
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT /id="PRO_5013418380"
FT TRANSMEM 600..622
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 254..319
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 321..379
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 383..444
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 429..563
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
SQ SEQUENCE 650 AA; 71587 MW; 12A8AD2105554104 CRC64;
MMVLRRIIRS FFILFLLAVP NSTVWTWNLD VREERIFRSL PKSYFGYNLN VYQPNETVTE
WLVGSPGENS FAGALYKCRS LDGEAGFGCD KVELMTRNRN AYIIPKNGWL GATVASSGGF
VLVCSPRAGP QTEGDCYSSE NNLNSFSKIQ LPYPRRVCLS GFSATYSPSA KTPRKPFLGG
PTCYHKDKPS TSSSLIFPAL YPELDQWYLG YAMASGLFGI RQFEQGEFLL LSVAFHIASS
FTGKVYLLKK ETKQELASLL GSQPGEHFGA SLAVSDINGD GRDDIIVGAP HYTDYESTDL
KVEIGAVYIY YQTSNNTYEQ NSSQELKGQV PGGRFGYAVA GIGDTDADGF NDVAIGAPYE
NEGFGTVYIY YGTNNGLRDR PSQVIFGNAF NPPIQTFGFA ITGGDFDGNK YSDVVVGGFE
SAAVAYIPAR PIAKINSKLN FVSEKINLEK TSQCSITNSS DGVTKIPVAC DDISFCITYS
GLSVADQVEL RVSILLDSNA EKGSRRIFFY ENKQEQFTQD IIYRAGFKKC LSRKFYVTPE
IQDTASTAQA RMTIELTTKI PEPNQLLPMF AGNFDKIVSN NSLVFMVSGK TSSFADATPW
WIYLVSALGA VLILSIITGV LYKLGFFKRK LPPTEQKEED NVTQASTDGM
//
