ID   A0A0N8H7K0_9HYPO        Unreviewed;      1098 AA.
AC   A0A0N8H7K0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Aminotransferase class I/classII domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AK830_g4599 {ECO:0000313|EMBL:KPM41988.1};
OS   Neonectria ditissima.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX   NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM41988.1, ECO:0000313|Proteomes:UP000050424};
RN   [1] {ECO:0000313|EMBL:KPM41988.1, ECO:0000313|Proteomes:UP000050424}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R09/05 {ECO:0000313|EMBL:KPM41988.1,
RC   ECO:0000313|Proteomes:UP000050424};
RA   Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT   "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT   ditissima.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00007441}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPM41988.1}.
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DR   EMBL; LKCW01000056; KPM41988.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0N8H7K0; -.
DR   STRING; 78410.A0A0N8H7K0; -.
DR   OrthoDB; 1328656at2759; -.
DR   Proteomes; UP000050424; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR010730; HET.
DR   InterPro; IPR004838; NHTrfase_class1_PyrdxlP-BS.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR24148; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR24148:SF73; HET DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G01020)-RELATED; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF06985; HET; 1.
DR   PRINTS; PR00753; ACCSYNTHASE.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00105; AA_TRANSFER_CLASS_1; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050424}.
FT   DOMAIN          182..334
FT                   /note="Heterokaryon incompatibility"
FT                   /evidence="ECO:0000259|Pfam:PF06985"
FT   DOMAIN          749..1093
FT                   /note="Aminotransferase class I/classII"
FT                   /evidence="ECO:0000259|Pfam:PF00155"
FT   REGION          695..737
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        704..737
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1098 AA;  121570 MW;  F97A250A9B3BBB26 CRC64;
     MCKAFVKQVY AKGPQKLPPL VLHDGLHAVK TYHAVAQIID VSVRNAAIKA SLLAHRPTDY
     FNSPIVSGII LALNHLDPTG FGGTGMACEY TYRPLTQPDE IRVLTLNPGS GAHDLEGTIS
     HMQLPDSAFT QPPSFDDDLE SVWKWNPIPS QNGFSSQIRV GELTNAQTKA SFIRSAYTQT
     EYDALSYTWG NSTKTDMITV NHNSLGITEN LHAALIHLRS PVEERRLWID AICIDQTNIQ
     ERNHQVQLMK RIFSGASSVI VWLGGAEGDV GSALQMMQDS MSSEYGDDAF NTLNTFQKVL
     NALSNVFKYS ENLLKGLTKL FNRSWWRRMW IVQEVVMARD LVVLLGDIIV PWSFLTRLCY
     EIQQNEYRQQ PLGPLFRACG YKRFTALQNF RENGSIPLAR LLQDTRDYQA SDPRDKLYAL
     LGITSDVTTA ELIPDYAKPV ERVFEDLVKF VAMQQDNLDI LSSGRHFCVS GHGSQSWLPD
     WQNSSGLRPL NIKRAPYNAA DGTRAIVDMS QFPRVLIVEA FVVDTVKLFG GSAPLAHEHL
     PTIRCRHYVA AQKPNIKTME LFWRMITADV DHLGNRATLA FKRQIHSFVN DADKRRPNPT
     SDFSDAATRA VIGRRFFITR SRRLGLAPAD IQLEDTVVII KGCRVPLIIR AVGNHWVLIG
     EAYVSGIMYG EVISGWKLEP ERHLQGTHQF LDAGNRRGDG LCQPTRKSPT TTLITQPLSS
     HDNNDNNDSH LHSPPTKTHL SADSLLYRGS VAGGPRFPQA LATHLNEYLA PHTPIAAASV
     QCVGAATAMH DILAWAVADA GDAVLTSRPV YGRFELDFGN KAQVRVVYAD THPEDCFDES
     VVERFEEALR RSRAEGVEVK MVLIVNPNNP LGKCYPRATL VAIMRFCQTH QLHLLSDEIY
     ACSVFGTDSP DAAPFTSALA IDAAGLLDPA LLHVTYGLSK DFGAAGLRLG AVVTRSRPVL
     AAVAAAVRFH NPSGPSLAVA TAMLEDRRWC RAFVASSRVK LAAAHAHVTG GLRGMGVRYL
     AESNAGFFVW VDLSPYLPAE LGGEANAEFA LARKLMDAGV FLHPREEHSS RPGWFRLVYT
     QDPETVTEGL RRIKIAIS
//