ID A0A0N8HXR7_9MICC Unreviewed; 1494 AA.
AC A0A0N8HXR7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Multifunctional nuclease/2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase {ECO:0000313|EMBL:KPN18233.1};
GN ORFNames=AO716_10185 {ECO:0000313|EMBL:KPN18233.1};
OS Arthrobacter sp. Edens01.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=1732020 {ECO:0000313|EMBL:KPN18233.1, ECO:0000313|Proteomes:UP000054460};
RN [1] {ECO:0000313|EMBL:KPN18233.1, ECO:0000313|Proteomes:UP000054460}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Edens01 {ECO:0000313|EMBL:KPN18233.1,
RC ECO:0000313|Proteomes:UP000054460};
RA Couger M.B.;
RT "Draft Genome of Arthrobacter sp. strain Edens01.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPN18233.1}.
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DR EMBL; LKIU01000005; KPN18233.1; -; Genomic_DNA.
DR RefSeq; WP_055240707.1; NZ_LKIU01000005.1.
DR STRING; 1732020.AO716_10185; -.
DR OrthoDB; 1016457at2; -.
DR Proteomes; UP000054460; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR CDD; cd10283; MnuA_DNase1-like; 1.
DR CDD; cd04486; YhcR_OBF_like; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR008334; 5'-Nucleotdase_C.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR006179; 5_nucleotidase/apyrase.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR047971; ExeM-like.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR NCBIfam; NF033681; ExeM_NucH_DNase; 1.
DR PANTHER; PTHR11575:SF48; 5' NUCLEOTIDASE, ECTO-LIKE; 1.
DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR Pfam; PF02872; 5_nucleotid_C; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF00932; LTD; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR01607; APYRASEFAMLY.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS51841; LTD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054460};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..1494
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006026715"
FT DOMAIN 25..166
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT REGION 172..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1494 AA; 154188 MW; 485CEDA5D604711B CRC64;
MRFTRWRAAL GTALSAGLLA GPLAALPAHA EEAAPSGVVI NEAYLSGGSA NAPFTNKFVE
LYNPTSSAVS LDGWSLQYRA AGSTGAPTGI GRLSGSIPAG GYYLIQGASN GSSGVALPAA
DATIGASFSG ASGTLVLANQ AAAVNPLPTG SVTTQPGVVD LLGYGSSNTF ETAPATAPAG
NSDPKSLNRT DFADSNNNAA DFALSTSVTP TNTAGTGTVP DPEPTDPEPT DPEPTDPPAG
TVAIAEIQGT GDASPLVGAN VTTRGNVTAA YPTGGFSGYY IQTPGTGGEL DPATHTASDG
IFVFSAATVG QVAVGDYVEV TGTVGEYFGL TQLTVPAGSM TKLSEAAEEV KPATVPWPAT
DTERETLEGM LLAPQGEFTV TDNYTLNQYA EIGLAAGSET LVQPTAVAPV GTPEHAAVVA
NNAAKAVKLD DGATTNFLSA ANQSKPLPYL TSTDPVRIGA PVSFTTNVIL DFRNSAWRFQ
PLTELTPANA ETVQPASFEN TRTAAPQSVG GNLKLAAFNV LNYFSTTGDD LTGCTYYNDR
SGAPVTVRGG CDARGAANEA NLDRQQAKIV AAINSLGADV VGLMEIENSA ELGQDRDTAL
AHLTEALNAA APGTWDYVRS PAALPDDEDV IRTAFIYRTA TAEPVGDSVI LNDESVFSNA
REPLAQAFKP AGGEDSESFV AIANHFKSKG SAPSSGENAD NGQGGWNADR VRQAQAVAEF
ADTVAQEAGT ERVFLLGDFN SYAAEDPMQV FAEAGYVNLG KATGKHSYAF SGLVGSLDHV
LASPAAAEDV TGTDIWNINS VESIAFEYSR YNYNATDYYA ADPYRSSDHD PILVGMDLTP
AEAEVTDLNL LNINDFHGRI DANTVNFAGT VEQLKAAAPE GSSLFLSAGD NIGASLFASS
VQEDQPTIDV LNALDLRASA VGNHEFDGGF ADLTDRVVPA SQFEYLGANV YLKGTTTPAL
PEYTILDVDG VQVAVIGAVT EETGTLVSPG GIADLEFGDP VEAVNRVAEQ LVADGLADVI
IAEYHEGAGS GTPDGASLEE EIAGGGAFAE IVTETSALVD AIYTGHTHKQ YAWDAPVPGV
DGKTRPVVQT GSYGEFIGQI ELAYNAETDE VLSYTAGNVA RTTTPAADLV AAYPAVAEVS
RIVDAALAYA AEVGNQPIGS VTADITTAFA GTSRDDRGNE STLGNLVADS LLSSLGSPER
GGAEIGVVNP GGLRAELYYG EDGVITYAEA NAVLPFVNNL WTTTLTGAQL KSVLEEQWQP
DGSSRTFLAL GLSDNVTYTY DPDQPRGSRI QSVTVNGEAL DTTRAYRVGT FSFLAQGGDN
FSTFAQGTDT RDSGLIDRDA WISYLQASSP VSPDFARQGV IVKAAPANVQ AGSSVSFAVD
KLDLTSLGSP ANTTLAVSWV PAGGTAVALG SVPVTAGAAS VTAAIPASAS GNGTLVLTAD
PSGTTVSIPV TVDEAPQQPT CIRPVPPKNW WDVRGWLKYA VDYARYLICT ISRG
//
