ID A0A0N9HRC0_9PSEU Unreviewed; 6204 AA.
AC A0A0N9HRC0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:ALG07358.1};
GN ORFNames=AOZ06_10870 {ECO:0000313|EMBL:ALG07358.1};
OS Kibdelosporangium phytohabitans.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Kibdelosporangium.
OX NCBI_TaxID=860235 {ECO:0000313|EMBL:ALG07358.1, ECO:0000313|Proteomes:UP000063699};
RN [1] {ECO:0000313|EMBL:ALG07358.1, ECO:0000313|Proteomes:UP000063699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLBMP1111 {ECO:0000313|EMBL:ALG07358.1,
RC ECO:0000313|Proteomes:UP000063699};
RA Qin S., Xing K.;
RT "Genome sequencing of Kibdelosporangium phytohabitans.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP012752; ALG07358.1; -; Genomic_DNA.
DR RefSeq; WP_054289326.1; NZ_JADBEI010000002.1.
DR STRING; 860235.AOZ06_10870; -.
DR KEGG; kphy:AOZ06_10870; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000063699; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 3.
DR CDD; cd17652; A_NRPS_CmdD_like; 1.
DR CDD; cd12117; A_NRPS_Srf_like; 1.
DR CDD; cd19543; DCL_NRPS; 1.
DR CDD; cd19534; E_NRPS; 3.
DR CDD; cd19531; LCL_NRPS-like; 3.
DR Gene3D; 3.30.300.30; -; 5.
DR Gene3D; 3.40.50.980; -; 6.
DR Gene3D; 1.10.1200.10; ACP-like; 5.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 8.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 8.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 5.
DR NCBIfam; TIGR01720; NRPS-para261; 3.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 5.
DR Pfam; PF13193; AMP-binding_C; 5.
DR Pfam; PF00668; Condensation; 8.
DR Pfam; PF00550; PP-binding; 5.
DR SMART; SM00823; PKS_PP; 5.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 5.
DR SUPFAM; SSF47336; ACP-like; 5.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 16.
DR PROSITE; PS00455; AMP_BINDING; 5.
DR PROSITE; PS50075; CARRIER; 5.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 5.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000063699}.
FT DOMAIN 938..1012
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2322..2397
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3296..3370
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4707..4782
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5705..5779
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1624..1644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 6204 AA; 676767 MW; 51E105A0557EDCBC CRC64;
MASRADRISA LPEHLREALR KRLAGQATSD TIPRADRDGP LPLSFSQRRL WFLSEFQPDE
TEYNSAFALR LTGQLDAGAM AAALQELSRR HESMRTTFDE VDGEGVQIVH PAVDLPLPVV
DCAAGDVDDV LRAEFGRPFD IRRGPLFRAV LVRLSDQEHI LLLSSHHIVV DGWSMGVLAD
ELSVLYAGGK LPEISLQYAD FAVWQREQDL ASHLDYWRQH LDAITPLELP TDRARPAVRT
SAGTTHEFTI PATLTARLAD LARASDTTLF SALLAGCQAL FARYAGQDDI ALGTVTSGRG
RTELERLVGF FVNTVVVRST VDSSRSFASL LAGTRDTVLD AFAHDAVPFD QLVHAERDLS
RNPLFDVMVL LQNADRPLPV FPGLRVEEVS LPRWASNFDI TVEFRERGGR VDGVLEYNTD
LFEANTIQRM AEHLVALLDA ATATPEAPVG DLVLGEVPDG HGASVAVPDL TYRALFESQV
SKTPDKRALV FQDREYTYAE LDSWADRIAH WLISQGAGPE SIVALALPRT AEMIAAIVAV
FKTGAVYLPI DPKQPADRIQ EIVEDARPVV VVTALPDLSG QPGTGPVNPL RADHAAYVIY
TSGSTGKPKG VVVEHRQLVN LVFNHRAEFP ADMRVALTAV FSFDTSLEGL VFLADGHELH
LIDESVRLDP EALVDYVATR RIDFMDLTPS FLQQLIPAGL LDHARILMLG GEALGESLWR
QLAKSDVRAH NFYGPTECTV DALSCEVTGD RPVIGRPLRN LRAYVLDDRM RPQPVGVPGE
LYLAGAQVAR GYLNRPGLTA DRFVASPFEP GTRMYRTGDR ARWTDAGMEY LGRTDDQVKI
RGFRIEPGEV EAALLRHPGV AEAVVVARED NGHKRLVAYV VPVGALDLRG WLKGILPDYM
VPSVFVELDE LPLTPSGKVD RRALPVPEFG TDAKGAVPPR TEVERELVRI WSDVLGVGPI
GVLDNFFGLG GDSILSIQVV ARARQAGIRL TSLDIFRHQT IAELATGVRI TAQADAPAAE
PAGPAPLGPI QRWFFDTHGE LAHYTMSVLL DLTPDVDISV LRSAFEAVVA HHPALTTSFG
DGQQVAGAGT GVFEVGTPLT RDGLDPAAGR MIKAVLDGTR LLVAVHHLVM DGVSWRILLD
DLETAYRQLR AGQPVDLPPV STPFGGWTRR LAGHVAAGGF DDDIAFWRTG SEHAALPVDA
NGRNTAGLTR RIQVKLAEAD TESLLHRVPE AYRTQVNEVL LSALGRVLAQ WTGRDEVAVA
VEGHGREEIF DDVDLSRTIG WFTTQFPVVL RMPGDNWGDT LKSVKEQLRA IPRRGLSYEA
LKYLGGQSFA GLPQICFNYH GAFDLTGGTG LVRGRLDSPG QDIPAGEPRT YLLDVTGLVE
AGELTLTWEY SSEVHDEQTV RTLAERYLDA LRAIIEHCLS PGAGGRTPSD FPLAKLTQTQ
VDRLGPTVDD VYPLTPLQAG MLFHSLVEAD AYVDEIEIVL DGVTDARALG AAWQRVVDRT
PVLRTSVLWQ DVDQPVQVVH RDVVVPVTYG KPEPGGFDLT QAPLTRIAIE QITAGQVRVT
WTSHHILLDG WSTAQVFAEV CDEYRGAAAI TRRPFRDYLR WLGTQDHKAA QQYWRDTLSG
VDGKTPLPYD RPSREAHQAE STESVKLTLA ADGPRRIAQG NGLTINTIVQ GAWALLLGRH
SGQSDVVFGT TVSGRPAELA GVESMVGMFI NTVPARVGLT ASRNVATWLR DLQSAQSESR
RHDFVSLAQI QSTGSLFDSV VVFENYPLSD ATTEPRVVGV RAKDNTTFPL TLSAHVADQL
HLDLAYDPRL FDRETVQRMA GRLEAIITGL DPAASLGQVP WTAPHEQELV LAQGAGARID
VPDLTYPEIF HEQVTRTPDR TALVFQGRRY TYAELNAEAN RLAHWLVGQG AGREQVVALK
LPRTADMITA ILAVFKAGAV YLPIDRELPQ SRVDAMVADA RPIVTLEALP ELDDWSDAEV
MPPQGHHAAY VIYTSGSTGL PKGVVVEHRS LVNLLANHRA VFPADMRVAL TAAFSFDTSL
EGLVLLASGH ELHLIDDEVR RDPEALVGYV ESNRVDFLDL TPSYLRQLIP AGLLEHVRVL
MLGGEALDEA LWRQLRDVQA YNFYGPTEAT VDTVWCRIAG ERPVIGHAVA NQEIYVLDAR
MSPVPPGVPG ELYLAGSQLA RGYLNRPGLT AERFVANPFT PGRMYRTGDL VKWTGSGIEY
LGRTDDQVKI RGFRIEPREI ETRLTQHPDV RAAAVIARGG RLIAYVAGRT DGLRAYLSEI
LPDYMVPATF VPLAELPLTT SGKLDKRALP EPDFPASDGY VEPVGRAETA VALIWADVLG
AARVGAQDNF FELGGDSILS ITVVSRLRAE FGVQLSPRVI FQNPTVAALA AAIPLEGDDE
PIPRTSRDVV PLSFAQQRLW FLDQFEPDST EYITPTVLRL RGRLDLDRLN RALTALVARH
ESLRTTFRAE SQVIHPPSDV EAPVIDVAEA DLDRVLAIES RKPFDLGTGP LVRAAVLRVS
DVDHVLVLSL HHIVTDGWST GVLTQDLGAL YNGSPLDELP IQYADFAAWQ RDKLSEPVLS
GQLDHWRRAL DAIEPLRLPT DRPRPPVFTS AGAMVEFSVP ADVLARLREV SRAKDGTLFM
TLITACQALL ARYTGQDDIA IGTVASGRDR AELDQVVGFF VNTLVLRSTV DLSGTFDDCL
ASVRQTVLAA FANQEVPFER VVDAVQPVRD TSRNPLFDVM VLLQNTPAAP PQLHGLTVDE
VAVPVVSAAC DLTFEFEERN DVLLGAIEYN TDLFDASTIE RMAGHLVTLL AGVTGPRRLA
DLLTADDRIP TTTHPVPDAT YPHVFEAQVA RTPDRTALVF QDEALSFAEL NARANRLAHW
LIAQGAGPEQ VVALALPRSA DMIVAILAVF KAGAVYLPLD PDLPGDRKEF IRQDVNPLLV
LDHVPDSGDT TDPVTPLRGD HAAYVIYTSG STGLPKGVVV EHRSLVNLLA NHRAVFPADM
RVALTAAFSF DTSLEGLVLL ASGHELHLID DEVRRDPEAL VGYVESNRVD FLDLTPSYLR
QLIPAGLLEH VRVLMLGGEA LDEALWRQLR DVQAYNFYGP TEATVDALSC RVTGDRPVIG
LPLRNLRAYI LDDYLRPVPE GLPGELYLSG PQVARGYLNR PGLTASRFMA DPFERGRMYR
TGDRVRWTGD GVEFLGRTDD QVKIRGFRIE PGEVEACLLD HPQVRAAAVI ARDNRLVAYV
VGPTAGLREH LGERLPDYLV PSVFVELDQL PLTISGKLDR RALPDPEITV DTELVAPRNE
IERTLAGIWA EVLGVPQVGV ADNFFALGGD SILSIQVVSR ARQAGLKLTS KDVFLHQTIA
RLAAVTTETT VRQVAEITGP APLTPIQHWF FEHGAPKHFT MSMFVELTED VDETALREAL
TAVVERHEAL RTRFFTENTE WRQDVGPAAG FFSHAGEGSP DAVALAAQSG VDFEEGPLLR
AVLFPGNKLL LAVHHLAIDG VSWRILLADL ETAYHQIAAG QPVKLGQPGV SFRQWAHRLN
EHVKSGGFAD SAWEQAPTGI PVDREGPNTA ASAQTVQVRL SRAETSALLH DVPGVYRTQV
NDVLLSALGR ALARWTGRDE VAVTLEGHGR EELFDDIDVS QTVGWFTTQF PVRLEIPDAG
WGRTLKSVKE QLRAVPDRGV SYEALKYIGG RSFGDLPEVC FNYHGQWGAS EQRGLFAGTL
PAIGADVAPD HDRGFLVDIT GAVEDGELRL DWEYSGNIHD HDTVHAVAQD AVAALREIIE
HCAQSEGGYT PSDFPLASLT QDQLDRLGTG IEDIYPLTPL QAGMLFHGLT DTNAYFNETR
VRLTGVTDIQ RLADAWQATV DAHPILRSSV LWEGVDKPLQ VVHKRVSLPV NTDHRLDLTT
VPLMSLAITP LPGDEVDLVW TAHHMLLDGW SNAQVFTEVI ERYTGHHKPV HRRPFRDYLD
WLTRQDTTEA DRHWRAVLAG IESPTPLPFD RPPAASHQSE STAAVSIALP ADRLNDVARR
HGLTVNTLVQ GAWALLLARY GRVRDVVFGT TVSGRPAELP GAESMIGMFI NTVPTRITIG
GRQALAHWLG EIQQAQAESR RFESSALNRL HSLSGVPVGE SLFDSIVAFE NYPIGEETIP
GAPGVEELDG MDTTNFPLAV RAYLDDRLHV ELGYDPHLFD EVTIQRLAKR LRLLIAAIPD
HLERPVDDLP WMTGAEQERA LAEWTGPVTG LPDVSIPELF EAQADRIPDV PAVGALTYRE
LNTRANRLAH QLRVRPDERV GVLMERSADL VVALLAIAKA GGAALPLDSR APLDRLRSLL
VESGVSVLVT DESWQAVAEQ IHSGDIVQAT VDGPGHNPGV RVHPDQLAYV MYTSGSTGKP
KGVAVRHRDV IALSRDQRLR GHERVLFHSP QAFDASTYEI WVPLLNGHSV VVAPPGEIDT
ALLRRMIADH GVTALWLTVG LFRMVAADDP SCLAGVREVW TGGEAVPASA IRRVRAACPD
VTVVDGYGPT ETTTFATCHP VDDLGESVPI GRPLDNTRTY VLDDRLRPVP PGVPGELYVA
GAGLARGYLD RPGLTAQRFV ADPFFPGERM YRTGDVVRWT GVLDYLGRSD DQVKIRGFRI
EPGEVAAVLS AHPSVTDIAV IARDKKLIAY VVPAVDPALP DFATRMLPDY LVPSAFVGLD
DLPLTGNGKL DRRALPDPAV EKRGYAEPET AAEHAIAEIW ADLLGQDRVG AHDNFFELGG
DSILSIQVIS RIRAVLGADV SARAVFDTPT VAGLAAGIAR EASAAIPVRP RDGALPLSYA
QQRLWFLNEF EPESTEYVTP LAVRLRGELD ADVLSRALNR LVDRHESLRT TFGSVDGKGV
QVVHAHVDVA LPVIDVTDAE QALVEESRTP FDLTTGPLLR ARLLRIAPDE HVLGLVMHHI
VTDGWSGGVL IRDLAELYRS ELTETPAELP ELPIQYADFA AWQREQDTSG QLGYWRERLD
SVVPVELPTD RPRPAVHTDN GDIVEFGVSR QTADHLKLPD STLFMALVAA CQLVLRRWSG
QDDIAVGTVT SGRLRAELEE LTGFFVNTLV LRSTVDATGT FASHLAGVRE TVLEAFAHQD
VPFEHVVDAV QPGRDTSRTP LFQVMVVLQN TPDNTIDLPG LTAEDVDLPV VTASFDITCE
FRETPDGLRG VVTYNTDLFD AATIRRFTEH LTMVLEAVAA DPDRPIDELP ATTQAEQDLM
ATWNDTAHPV VPMTFPELVE AQVARTPDAP ALLFDGGSMT YAELNARANR LARRLAEDGA
GPERIVAVML PRSVEIIVAE LAVAKTGAAF LPVDPAYPQA RIDFMLADAG PVLVLASGQD
TADVDGDSSD LVVERRLEHP AYVIYTSGST GRPKGVVVSH AGLASFSAAQ RAHYDVRPGD
RVLEFSSPSF DASVLELCMS LTVGASLVVP PPGPLLGDHL AQVLRDNQVT HALIPPAALA
TVPEVALPDF RCLIVGGDAC SAELVSRWSA GRRMINAYGP TESTVVTSWS APLTPGGTPP
IGGPIWNTQV RVLDGRLRPV PIGVTGELYV SGHGLARGYL NRPGLTAERF VADPSGDGTR
MYRTGDLVRW TTGGALEFIG RADDQVKIRG FRIELGEVEA ALRTHPSVRS CVAVVREDDG
HKRLVAYTVP EVPAGIRELL GRSLPEYLVP AVFVPLDELP VSPNGKVDRA ALPEPGVQPD
EGHVAPTGPI ETALAAIWAD VLGLSRVGVH DSFFKLGGDS ILSIQVVARA RQAGLRIATK
DVFLHQTIAS MAPLVTVIES ADDDRAPVTG PVPLTPIQRW FFAERHGDPH HFNQSHFVEL
APEVNVAALR SAIAALLVHH DALRMRFTVT DGVWSQENAP VTPVEVLQVV TDADMEEVAD
SVHASFDLGS GPLLKAVLFD GPAPHLLLVA HHLVVDGVSW RVLLDDLDTA YQQALRGDPA
DLGPKTTSFR DWSHKLTEYV EGGGLDQELD FWSGVRVVDL PADQPSAGAA EPVDSVGTLL
SAEDTDALLR GAPVAYRTGL HDVLLAACTW AFGEGATVSI DLEGHGREDV IDDVDLSRTV
GWFTSMYPVT VTVPTGGWRD IVKTVRRQLR AVPRNGFGYG PLRYLTDRLP PVPRPQVSFN
YLGQFDSGGG EAGSGLYRAV KTSIGRDQDE SAQPEHLIDI VGEIGDGRLG FTWYFRTDSH
RRGTVTALVD RFTTALRAMA EECR
//
