ID A0A0N9IAU3_9PSEU Unreviewed; 557 AA.
AC A0A0N9IAU3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=3-ketosteroid-delta-1-dehydrogenase {ECO:0000313|EMBL:ALG13512.1};
GN ORFNames=AOZ06_47560 {ECO:0000313|EMBL:ALG13512.1};
OS Kibdelosporangium phytohabitans.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Kibdelosporangium.
OX NCBI_TaxID=860235 {ECO:0000313|EMBL:ALG13512.1, ECO:0000313|Proteomes:UP000063699};
RN [1] {ECO:0000313|EMBL:ALG13512.1, ECO:0000313|Proteomes:UP000063699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KLBMP1111 {ECO:0000313|EMBL:ALG13512.1,
RC ECO:0000313|Proteomes:UP000063699};
RA Qin S., Xing K.;
RT "Genome sequencing of Kibdelosporangium phytohabitans.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP012752; ALG13512.1; -; Genomic_DNA.
DR RefSeq; WP_054295400.1; NZ_JADBEI010000001.1.
DR AlphaFoldDB; A0A0N9IAU3; -.
DR STRING; 860235.AOZ06_47560; -.
DR KEGG; kphy:AOZ06_47560; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000063699; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000063699};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..557
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006036012"
FT DOMAIN 28..542
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 557 AA; 57976 MW; FEB76340527A5364 CRC64;
MAGATRRSVL AGAGLAVLAT PAEASESDVV VVGAGAAGMT AALTAAKRGL RTVVIEKAST
YGGSAARSGA GIWIPNNSVI LAAGVPDTPQ KAAAYMSAVV GATVPLVRQQ AFLQHGPAMP
NFVMANSPLR FRWMEGCSDY YPELPGDMPN GRSIEPDMLD GKTLGAELAR LNPSYIPTPP
GLVVFSADYK WLNLAAANAK GFAVAAECAA RATAAALAGK KPLTMGQALA GGLRAGLQQA
GVPVLLNTPL TELHVENGVV KGVVTPQGLT RATRGVIIGS GGFEHNAPMR ARYQRQPTGW
SVGAKANTGD GILAGQRLGA ALDLMDDAWW GPAIPLPDQP YFCLAERTLP GGLMINQAGR
WFVNEAAPYG DVVHVMYDKA MVPAWLIIDQ NYRNRYLFKD VAPSLPFPQS WYDSGAVVKA
PTIEALAAAI SVPPATLRAT VARFNGFALA GRDRDFWRGD SAYDHYYTDP AVLPSSSLSS
LWLPPFYAFK IVPGDLGTKG GMRTDAQARV LRADGSVIGG LFAAGNASAA VMGTSYTGAG
ATIGPAMTFG FIAANAV
//
