ID   A0A0N9Q9E4_CEV01        Unreviewed;       604 AA.
AC   A0A0N9Q9E4;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=glutamine--fructose-6-phosphate transaminase (isomerizing) {ECO:0000256|ARBA:ARBA00012916};
DE            EC=2.6.1.16 {ECO:0000256|ARBA:ARBA00012916};
GN   ORFNames=ceV_243 {ECO:0000313|EMBL:ALH23149.1};
OS   Chrysochromulina ericina virus (CeV01).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Algavirales; Phycodnaviridae.
OX   NCBI_TaxID=455364 {ECO:0000313|EMBL:ALH23149.1, ECO:0000313|Proteomes:UP000203826};
OH   NCBI_TaxID=156174; Haptolina ericina.
RN   [1] {ECO:0000313|EMBL:ALH23149.1, ECO:0000313|Proteomes:UP000203826}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CeV-01B {ECO:0000313|EMBL:ALH23149.1};
RX   PubMed=26634761;
RA   Gallot-Lavallee L., Pagarete A., Legendre M., Santini S., Sandaa R.A.,
RA   Himmelbauer H., Ogata H., Bratbak G., Claverie J.M.;
RT   "The 474-Kilobase-Pair Complete Genome Sequence of CeV-01B, a Virus
RT   Infecting Haptolina (Chrysochromulina) ericina (Prymnesiophyceae).";
RL   Genome Announc. 3:e01413-e01415(2015).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-
CC         phosphate + L-glutamate; Xref=Rhea:RHEA:13237, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:58359, ChEBI:CHEBI:58725, ChEBI:CHEBI:61527; EC=2.6.1.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001031};
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DR   EMBL; KT820662; ALH23149.1; -; Genomic_DNA.
DR   RefSeq; YP_009173498.1; NC_028094.1.
DR   GeneID; 26049110; -.
DR   KEGG; vg:26049110; -.
DR   OrthoDB; 3394at10239; -.
DR   Proteomes; UP000203826; Genome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; IEA:UniProtKB-EC.
DR   GO; GO:1901137; P:carbohydrate derivative biosynthetic process; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd05008; SIS_GlmS_GlmD_1; 1.
DR   CDD; cd05009; SIS_GlmS_GlmD_2; 1.
DR   Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR   InterPro; IPR017932; GATase_2_dom.
DR   InterPro; IPR005855; GFAT.
DR   InterPro; IPR035466; GlmS/AgaS_SIS.
DR   InterPro; IPR035490; GlmS/FrlB_SIS.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   NCBIfam; TIGR01135; glmS; 1.
DR   PANTHER; PTHR10937; GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING; 1.
DR   PANTHER; PTHR10937:SF0; GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); 1.
DR   Pfam; PF13522; GATase_6; 1.
DR   Pfam; PF01380; SIS; 2.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR   SUPFAM; SSF53697; SIS domain; 1.
DR   PROSITE; PS51278; GATASE_TYPE_2; 1.
DR   PROSITE; PS51464; SIS; 2.
PE   4: Predicted;
KW   Aminotransferase {ECO:0000256|ARBA:ARBA00022576,
KW   ECO:0000313|EMBL:ALH23149.1};
KW   Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962};
KW   Reference proteome {ECO:0000313|Proteomes:UP000203826};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          2..226
FT                   /note="Glutamine amidotransferase type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51278"
FT   DOMAIN          288..429
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
FT   DOMAIN          457..594
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
SQ   SEQUENCE   604 AA;  68427 MW;  D83B7FA31A57D68A CRC64;
     MCGITIFFSK NRSDIIRKIL DSLYNIQNRG YDSIGISYLS DNLRDWCIEK YASTNSKDGI
     KQLEEKISNI KSSIAIGHTR WATHGARSDI NAHPHISMNK KIIVVHNGII TNFNVIKDML
     ISKGYKFISE TDTEVISNLL EDELSITKNI YTAIININKK LEGTWALGII NTEERDKIYI
     TRHGSPLLIG ENNKEIICCS EISGFIGQIN NYIVLNNDDI IIVDQNGYHT EREYNINKIN
     NISYETTPDP YKYWTLKEIY EQPKSINNAI NNGGRIKDND IVLGGLNYLQ NYKNSIDNII
     VLGCGTSYHA AMLFKYYMQN NKKFNIVTAY DASEFTELDI PNKGKTLFIV CSQSGETRDL
     INMLEICKKY DSITIGVINV VDSMLAKMVD CGVYLNAGLE KAVASTKSYT SMLIVLSLIA
     MWFNQNNNLM INNLRNISTT VSDILENDHI KNDCLNLVNF TNRNKIENMF ILGSGKLFSV
     AKEGALKIKE ISYIRAEGYS AGALKHGPFA LLDSKTIVIL LIDADNIEKL TSTYHEITAR
     ETNCFVITDV ETDLFKNKIV IPNVKYYNEI LFAIILQYIA YHLSVTRDIN PDRPRNLAKV
     VTVE
//