ID A0A0P0AEQ3_9RHOB Unreviewed; 639 AA.
AC A0A0P0AEQ3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:ALI56814.1, ECO:0000313|EMBL:SFK99722.1};
GN ORFNames=IMCC12053_2867 {ECO:0000313|EMBL:ALI56814.1},
GN SAMN05444421_11288 {ECO:0000313|EMBL:SFK99722.1};
OS Celeribacter marinus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Celeribacter.
OX NCBI_TaxID=1397108 {ECO:0000313|EMBL:ALI56814.1, ECO:0000313|Proteomes:UP000064920};
RN [1] {ECO:0000313|EMBL:ALI56814.1, ECO:0000313|Proteomes:UP000064920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC 12053 {ECO:0000313|EMBL:ALI56814.1,
RC ECO:0000313|Proteomes:UP000064920};
RA Wang D.B., Wang M.;
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SFK99722.1, ECO:0000313|Proteomes:UP000181863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100036 {ECO:0000313|EMBL:SFK99722.1,
RC ECO:0000313|Proteomes:UP000181863};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR EMBL; CP012023; ALI56814.1; -; Genomic_DNA.
DR EMBL; FOSM01000012; SFK99722.1; -; Genomic_DNA.
DR RefSeq; WP_062220084.1; NZ_FOSM01000012.1.
DR AlphaFoldDB; A0A0P0AEQ3; -.
DR STRING; 1397108.IMCC12053_2867; -.
DR KEGG; cmar:IMCC12053_2867; -.
DR PATRIC; fig|1397108.4.peg.2931; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000064920; Chromosome.
DR Proteomes; UP000181863; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000064920};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..236
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 269..595
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 607..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..628
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 70028 MW; 061252EE23963BAE CRC64;
MRRSPQDTAT SARKISRRAL FLGGSQLAFM GILGLRMRYM QVEQADEFRL MAEDNRIKVR
LLPPARGLLY DRNGAVIAEN EQTFRIVIRK EDANQIDQVL VELERLINLP PEDQTRVREE
LRKAGPSAPV TIADRLSWEA FSAVSANGPA LPGVTPEVGL SRRYPLHDDF AHMVGYVGPV
SDYNLSKMDV IDPLYRIPKF QIGKSGVESQ LEEDLRGRAG SLRVEQNARG RIIRELGRQE
GIAGANIQLT FDHKMQNFMQ ARLAGESAAA VILDIETGDV LASGSTPAFD PNLFVRGISV
ADYNALLENK YRPLPSKSVQ GAYPPGSTFK MVTALAALEA GVVTSDETVR CTGHTEVGGR
RFHCWKRSGH GNVNLVGSLR HSCDVYYYEL AQRTGIENIA EMGRKLGLGD SYALPLPGMS
SGLMPDKQWK LKNRGAEWVV GDSLNASIGQ GFVLTTPMQL AVMTARIATG RAVIPRLVKS
IDGVDQGIQG GEKIDINENM LRAVRQGMYE VSNSSRGTAY ASRIADATLQ MAGKTGTSQV
RNKVVNNNNV PWEERDHALF VSYAPYDNPR YAVSVVVEHG GGGSSTAAPI ARDLMLYALH
GDLPPLDSYP SSQRGTISER FRNLPLRDTS GSDTEKSRA
//
