ID A0A0P0G3D6_9BACE Unreviewed; 242 AA.
AC A0A0P0G3D6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Two pore domain potassium channel family protein {ECO:0000313|EMBL:KAA5405206.1};
GN ORFNames=BcellWH2_05130 {ECO:0000313|EMBL:ALJ62338.1}, DWW88_24455
GN {ECO:0000313|EMBL:RGU20722.1}, DWX97_23740
GN {ECO:0000313|EMBL:RGS32288.1}, F2Y70_11245
GN {ECO:0000313|EMBL:KAA5426049.1}, F2Y81_12000
GN {ECO:0000313|EMBL:KAA5418164.1}, F2Y86_19965
GN {ECO:0000313|EMBL:KAA5405206.1}, F2Y87_19360
GN {ECO:0000313|EMBL:KAA5416276.1};
OS Bacteroides cellulosilyticus.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=246787 {ECO:0000313|EMBL:ALJ62338.1, ECO:0000313|Proteomes:UP000061809};
RN [1] {ECO:0000313|EMBL:ALJ62338.1, ECO:0000313|Proteomes:UP000061809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH2 {ECO:0000313|EMBL:ALJ62338.1,
RC ECO:0000313|Proteomes:UP000061809};
RX PubMed=26430127;
RA Wu M., McNulty N.P., Rodionov D.A., Khoroshkin M.S., Griffin N.W.,
RA Cheng J., Latreille P., Kerstetter R.A., Terrapon N., Henrissat B.,
RA Osterman A.L., Gordon J.I.;
RT "Genetic determinants of in vivo fitness and diet responsiveness in
RT multiple human gut Bacteroides.";
RL Science 350:AAC5992-AAC5992(2015).
RN [2] {ECO:0000313|Proteomes:UP000283341, ECO:0000313|Proteomes:UP000285677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF17-25 {ECO:0000313|EMBL:RGU20722.1,
RC ECO:0000313|Proteomes:UP000285677}, and AF22-3AC
RC {ECO:0000313|EMBL:RGS32288.1, ECO:0000313|Proteomes:UP000283341};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000325055, ECO:0000313|Proteomes:UP000448877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A3 {ECO:0000313|EMBL:KAA5426049.1,
RC ECO:0000313|Proteomes:UP000475645}, BIOML-A6
RC {ECO:0000313|EMBL:KAA5418164.1, ECO:0000313|Proteomes:UP000448877},
RC BIOML-A7 {ECO:0000313|EMBL:KAA5405206.1,
RC ECO:0000313|Proteomes:UP000325055}, and BIOML-A8
RC {ECO:0000313|EMBL:KAA5416276.1, ECO:0000313|Proteomes:UP000482653};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
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DR EMBL; CP012801; ALJ62338.1; -; Genomic_DNA.
DR EMBL; VVYW01000019; KAA5405206.1; -; Genomic_DNA.
DR EMBL; VVYX01000025; KAA5416276.1; -; Genomic_DNA.
DR EMBL; VVYV01000018; KAA5418164.1; -; Genomic_DNA.
DR EMBL; VVYT01000028; KAA5426049.1; -; Genomic_DNA.
DR EMBL; QRVJ01000036; RGS32288.1; -; Genomic_DNA.
DR EMBL; QRXS01000020; RGU20722.1; -; Genomic_DNA.
DR RefSeq; WP_007209679.1; NZ_VVYX01000025.1.
DR AlphaFoldDB; A0A0P0G3D6; -.
DR STRING; 246787.BcellWH2_05130; -.
DR GeneID; 66308901; -.
DR KEGG; bcel:BcellWH2_05130; -.
DR PATRIC; fig|246787.4.peg.5298; -.
DR eggNOG; ENOG502ZAF5; Bacteria.
DR Proteomes; UP000061809; Chromosome.
DR Proteomes; UP000283341; Unassembled WGS sequence.
DR Proteomes; UP000285677; Unassembled WGS sequence.
DR Proteomes; UP000325055; Unassembled WGS sequence.
DR Proteomes; UP000448877; Unassembled WGS sequence.
DR Proteomes; UP000475645; Unassembled WGS sequence.
DR Proteomes; UP000482653; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000313|EMBL:KAA5405206.1};
KW Ion transport {ECO:0000313|EMBL:KAA5405206.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:KAA5405206.1}.
FT TRANSMEM 15..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 147..223
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
SQ SEQUENCE 242 AA; 27457 MW; 91DBCC23AEF5C1A1 CRC64;
MKMALSEFAL REKGIYGVLH IVILLLSLFL VVSISVDTFK GIPFYTQTVF MKVQFAVCIL
FLLDFILEWF LAKHKGRYFA THFVFLLVAI PYQSIISWAG WTFSEEITYL LRFIPLVRGG
YALAIVVGWL TYNKASGLFV TYLTTLLATV YFSSLAFYVM EHGVNTLVTG YGDALWWAFM
DVTTVGSNII AVTVTGRVLS VLLAALGMMM FPIFTVYVTS LVQKRNQEKQ EYYKELQGGD
IK
//
