ID A0A0P0GUI1_9BACE Unreviewed; 686 AA.
AC A0A0P0GUI1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Cytochrome C biogenesis protein {ECO:0000313|EMBL:ALJ62093.1, ECO:0000313|EMBL:KAA5418673.1};
GN Name=ccsA_3 {ECO:0000313|EMBL:ALJ62093.1};
GN ORFNames=BcellWH2_04884 {ECO:0000313|EMBL:ALJ62093.1}, F2Y81_11220
GN {ECO:0000313|EMBL:KAA5418673.1};
OS Bacteroides cellulosilyticus.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=246787 {ECO:0000313|EMBL:ALJ62093.1, ECO:0000313|Proteomes:UP000061809};
RN [1] {ECO:0000313|EMBL:ALJ62093.1, ECO:0000313|Proteomes:UP000061809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH2 {ECO:0000313|EMBL:ALJ62093.1,
RC ECO:0000313|Proteomes:UP000061809};
RX PubMed=26430127;
RA Wu M., McNulty N.P., Rodionov D.A., Khoroshkin M.S., Griffin N.W.,
RA Cheng J., Latreille P., Kerstetter R.A., Terrapon N., Henrissat B.,
RA Osterman A.L., Gordon J.I.;
RT "Genetic determinants of in vivo fitness and diet responsiveness in
RT multiple human gut Bacteroides.";
RL Science 350:AAC5992-AAC5992(2015).
RN [2] {ECO:0000313|EMBL:KAA5418673.1, ECO:0000313|Proteomes:UP000448877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A6 {ECO:0000313|EMBL:KAA5418673.1,
RC ECO:0000313|Proteomes:UP000448877};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP012801; ALJ62093.1; -; Genomic_DNA.
DR EMBL; VVYV01000016; KAA5418673.1; -; Genomic_DNA.
DR RefSeq; WP_033160710.1; NZ_VVYV01000016.1.
DR AlphaFoldDB; A0A0P0GUI1; -.
DR STRING; 246787.BcellWH2_04884; -.
DR GeneID; 66309133; -.
DR KEGG; bcel:BcellWH2_04884; -.
DR PATRIC; fig|246787.4.peg.5042; -.
DR eggNOG; COG0755; Bacteria.
DR eggNOG; COG1333; Bacteria.
DR Proteomes; UP000061809; Chromosome.
DR Proteomes; UP000448877; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR045062; Cyt_c_biogenesis_CcsA/CcmC.
DR InterPro; IPR007816; ResB-like_domain.
DR PANTHER; PTHR30071:SF17; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR30071; HEME EXPORTER PROTEIN C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR Pfam; PF05140; ResB; 1.
PE 4: Predicted;
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 481..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..175
FT /note="ResB-like"
FT /evidence="ECO:0000259|Pfam:PF05140"
FT DOMAIN 475..683
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
SQ SEQUENCE 686 AA; 78510 MW; 676CDAA19019EB02 CRC64;
MHLFNLKKSL VFLYICLVAL LAAVTFVEHV HGTEFVEKYV YHTVWFCCLW GVLAALAVAV
LVKRQLWRRL PTLLLHGSFL VILVGAMITF SYSKKGYMHL TVGTEVGTFI DQDSKRVIEL
PFTLCLDSFR VEYYPGTDAP ADYVSYIRDA EPVSMNRILS RQGYRFYQSS FDDDKEGSWL
SVNYDPWGIG ITYAGYILLG ISMLWMLVGR SGEFRRLLRH PLLRKGGMFV WLLMVTGAAM
QAENRSLPAL ALRQADSLAS KQVIYHDRVV PFNTLARDFV LKLTGKSSYG GMTPEQVVGG
WLLRPEVWQN EPMIYIKSAE LRHLLRLPSS YARLTDLFDG QNYRLQEFWK GEQKPHMKMT
SLEKAIMETD EKVGLILMLR SGTLIRPLPE DGSIKPLSDV KVQAEILYNR IPFSKLLFMF
NLTVGMLAFF YLLYCSMHRS AGKAWSVFTV ALYAAFLFQL FGYCLRWYIG GRIPLSNGYE
TMQFMALCTL LLACIFRRRF SFTLPFGLLI SGFALLVAYL GQNNPQITPL MPVLLSPWLS
IHVSLIMVSY ALFAFMMLNG LLAFCIGGWR KKTIDSEIQE QRKVRVEQLM LFSRLMLYPA
VFCLGAGIFI GAVWANVSWG RYWAWDPKEV WALITFLIYG AAFHGQSLAV FRQPRFFHAY
MVLAFLTVLM TYFGVNYLLG GMHSYA
//
