ID A0A0P0GYC0_9BACE Unreviewed; 456 AA.
AC A0A0P0GYC0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Sigma-54-dependent Fis family transcriptional regulator {ECO:0000313|EMBL:KAA5408479.1};
DE SubName: Full=Transcriptional regulatory protein ZraR {ECO:0000313|EMBL:ALJ62609.1};
GN Name=zraR_9 {ECO:0000313|EMBL:ALJ62609.1};
GN ORFNames=BcellWH2_05409 {ECO:0000313|EMBL:ALJ62609.1}, DWX97_08075
GN {ECO:0000313|EMBL:RGS37702.1}, F2Y81_06755
GN {ECO:0000313|EMBL:KAA5421126.1}, F2Y86_14010
GN {ECO:0000313|EMBL:KAA5408479.1}, F2Y87_08110
GN {ECO:0000313|EMBL:KAA5420324.1};
OS Bacteroides cellulosilyticus.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=246787 {ECO:0000313|EMBL:ALJ62609.1, ECO:0000313|Proteomes:UP000061809};
RN [1] {ECO:0000313|EMBL:ALJ62609.1, ECO:0000313|Proteomes:UP000061809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WH2 {ECO:0000313|EMBL:ALJ62609.1,
RC ECO:0000313|Proteomes:UP000061809};
RX PubMed=26430127;
RA Wu M., McNulty N.P., Rodionov D.A., Khoroshkin M.S., Griffin N.W.,
RA Cheng J., Latreille P., Kerstetter R.A., Terrapon N., Henrissat B.,
RA Osterman A.L., Gordon J.I.;
RT "Genetic determinants of in vivo fitness and diet responsiveness in
RT multiple human gut Bacteroides.";
RL Science 350:AAC5992-AAC5992(2015).
RN [2] {ECO:0000313|EMBL:RGS37702.1, ECO:0000313|Proteomes:UP000283341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF22-3AC {ECO:0000313|EMBL:RGS37702.1,
RC ECO:0000313|Proteomes:UP000283341};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000325055, ECO:0000313|Proteomes:UP000448877}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BIOML-A6 {ECO:0000313|EMBL:KAA5421126.1,
RC ECO:0000313|Proteomes:UP000448877}, BIOML-A7
RC {ECO:0000313|EMBL:KAA5408479.1, ECO:0000313|Proteomes:UP000325055},
RC and BIOML-A8 {ECO:0000313|EMBL:KAA5420324.1,
RC ECO:0000313|Proteomes:UP000482653};
RX PubMed=31477907; DOI=.1038/s41591-019-0559-3;
RA Poyet M., Groussin M., Gibbons S.M., Avila-Pacheco J., Jiang X.,
RA Kearney S.M., Perrotta A.R., Berdy B., Zhao S., Lieberman T.D.,
RA Swanson P.K., Smith M., Roesemann S., Alexander J.E., Rich S.A., Livny J.,
RA Vlamakis H., Clish C., Bullock K., Deik A., Scott J., Pierce K.A.,
RA Xavier R.J., Alm E.J.;
RT "A library of human gut bacterial isolates paired with longitudinal
RT multiomics data enables mechanistic microbiome research.";
RL Nat. Med. 25:1442-1452(2019).
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DR EMBL; CP012801; ALJ62609.1; -; Genomic_DNA.
DR EMBL; VVYW01000010; KAA5408479.1; -; Genomic_DNA.
DR EMBL; VVYX01000008; KAA5420324.1; -; Genomic_DNA.
DR EMBL; VVYV01000008; KAA5421126.1; -; Genomic_DNA.
DR EMBL; QRVJ01000005; RGS37702.1; -; Genomic_DNA.
DR RefSeq; WP_007214176.1; NZ_VVYX01000008.1.
DR AlphaFoldDB; A0A0P0GYC0; -.
DR STRING; 246787.BcellWH2_05409; -.
DR GeneID; 66308631; -.
DR KEGG; bcel:BcellWH2_05409; -.
DR PATRIC; fig|246787.4.peg.5582; -.
DR eggNOG; COG2204; Bacteria.
DR Proteomes; UP000061809; Chromosome.
DR Proteomes; UP000283341; Unassembled WGS sequence.
DR Proteomes; UP000325055; Unassembled WGS sequence.
DR Proteomes; UP000448877; Unassembled WGS sequence.
DR Proteomes; UP000482653; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF95; TRANSCRIPTIONAL REGULATORY PROTEIN ZRAR; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..125
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 155..384
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT MOD_RES 55
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 456 AA; 51583 MW; 01A0CE98F7C2E22A CRC64;
MEQLGKILIV DDNEDVLFAL NLLLEPYAEK IKVAVTPDRI EYFMTTFQPD IILLDMNFSR
DAISGQEGFE SLEQILRIDP QAVVIFMTAY ADTDKAVRAI KAGATDFIPK PWEKEKLLAT
LSSGIKLRRS RCEVNLLKEQ VEVLSGAGSS VEESIIGESA AMQEVFATIE KLRDTDANIL
VLGENGTGKD VIARLLYRCS PRYGRPFVTI DLGSIPEQLF ESELFGYEKG AFTDARKPKA
GRMEVATGGT LFLDEIGNLS LPMQAKLLTA IEKRQISRLG STQSVSIDVR LICATNADIR
HLVEEGNFRQ DLLYRINTIE LHIPPLRERG NDIILLADYF LQRYARKYQK EMRGLTREAK
AKLLRYSWPG NVRELQHTME RAVILGDGSL LRPDNFLFQA SSPRLKKEEE ILNLEQLERQ
AVEKAMRLSE GNMTRAAEYL GITRFALYRK IEKLGL
//
