ID A0A0P0M8K9_9BURK Unreviewed; 632 AA.
AC A0A0P0M8K9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Acetyl-coenzyme A synthetase {ECO:0000313|EMBL:ALK88450.1};
DE EC=6.2.1.1 {ECO:0000313|EMBL:ALK88450.1};
GN Name=acsA_2 {ECO:0000313|EMBL:ALK88450.1};
GN ORFNames=L63ED372_01239 {ECO:0000313|EMBL:ALK88450.1};
OS Limnohabitans sp. 63ED37-2.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Limnohabitans.
OX NCBI_TaxID=1678128 {ECO:0000313|EMBL:ALK88450.1, ECO:0000313|Proteomes:UP000059510};
RN [1] {ECO:0000313|EMBL:ALK88450.1, ECO:0000313|Proteomes:UP000059510}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=63ED37-2 {ECO:0000313|EMBL:ALK88450.1,
RC ECO:0000313|Proteomes:UP000059510};
RA Ahn J.-H., Kim S.B.;
RT "Limnohabitans sp. 2 strains.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP011774; ALK88450.1; -; Genomic_DNA.
DR RefSeq; WP_062404380.1; NZ_CP011774.1.
DR AlphaFoldDB; A0A0P0M8K9; -.
DR STRING; 1678128.L63ED372_01239; -.
DR KEGG; lih:L63ED372_01239; -.
DR PATRIC; fig|1678128.3.peg.1226; -.
DR OrthoDB; 9766486at2; -.
DR Proteomes; UP000059510; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR012694; Propion_PrpE.
DR NCBIfam; TIGR02316; propion_prpE; 1.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:ALK88450.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000059510}.
FT DOMAIN 5..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 60..448
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 513..596
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 632 AA; 68868 MW; 315A1DAE069E1F59 CRC64;
MGNFAEFHAR SINDRDVFWA EQAKLVDWKV QPQQICDYSN PPFAKWFVGG QTNLCHNAVD
RHLAERADQP ALIFVSTETN QERTYTFCEL HTEVQRMAAI LQDLGVVKGD RVLIYMPMIA
EAAFAMLACV RLGAIHSVVF GGFASHSLAT RIEDASPKVI ISADAGSRGG KGVPYKPLLD
EAIKLSAHKP VNVIMVDRKL AAFTPVAGRD VDYATERAKH MDAVVPCVWV ESTHPSYTLY
TSGTTGKPKG VQRDTGGYTV ALAASIPNVF EGKPGGTFFC TSDIGWVVGH SYIIYGPLIG
GMATILYEGL PIRPDGGIWW SLVEKYKVQV MFSAPTAIRV LKKQDPALLS KYDLSSLQAL
FLAGEPLDEP TAKWISEGLS GKAIIDNYWQ TETGWPILSI CNGVEKAPSK FGSPGKAIYG
YNVKLVDDQT GEELTGANQK GVLTIEGPLP PGNLQTIWGD DERFVKTYWK TVPNKLVYST
FDWAVRDEDG YFFILGRTDD VINVAGHRLG TREIEESISS HPNIAEVAVV GVADQLKGQV
AMAFAIAKDT SGLTDAAARL KLEGEVMKVV DSQLGAVARP SRVFFVSALP KTRSGKLLRR
AIQAVAEGRD PGDLTTMDDP AALQQIVDQI QG
//
