ID A0A0P0QKD5_9VIRU Unreviewed; 803 AA.
AC A0A0P0QKD5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=NS3-like protein {ECO:0000313|EMBL:ALL52907.1};
OS Shuangao insect virus 7.
OC Viruses; Riboviria.
OX NCBI_TaxID=1746063 {ECO:0000313|EMBL:ALL52907.1, ECO:0000313|Proteomes:UP000202570};
RN [1] {ECO:0000313|EMBL:ALL52907.1, ECO:0000313|Proteomes:UP000202570}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SKC {ECO:0000313|EMBL:ALL52907.1,
RC ECO:0000313|Proteomes:UP000202570};
RX PubMed=26491167; DOI=10.1128/JVI.02036-15;
RA Shi M., Lin X.D., Vasilakis N., Tian J.H., Li C.X., Chen L.J., Eastwood G.,
RA Diao X.N., Chen M.H., Chen X., Qin X.C., Widen S.G., Wood T.G., Tesh R.B.,
RA Xu J., Holmes E.C., Zhang Y.Z.;
RT "Divergent Viruses Discovered in Arthropods and Vertebrates Revise the
RT Evolutionary History of the Flaviviridae and Related Viruses.";
RL J. Virol. 90:659-669(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KR902719; ALL52907.1; -; Genomic_RNA.
DR RefSeq; YP_009179402.1; NC_028397.1.
DR GeneID; 26217620; -.
DR KEGG; vg:26217620; -.
DR OrthoDB; 5539at10239; -.
DR Proteomes; UP000202570; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.10.120; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011492; Flavi_DEAD.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR PANTHER; PTHR43519; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR PANTHER; PTHR43519:SF1; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR Pfam; PF07652; Flavi_DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Capsid protein {ECO:0000256|ARBA:ARBA00022561};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW Reference proteome {ECO:0000313|Proteomes:UP000202570};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Virion {ECO:0000256|ARBA:ARBA00022561}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 395..554
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 557..723
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 803 AA; 90252 MW; 3B565DF4B18165DD CRC64;
MFGQVKLLKL GVIDMRLSMF VTLMIGNCVT TFTSHMKWWA PILYYVLVVE KGLMEWKRKE
SSTVYYVLMG LLLFFGIHYL MPTVFFLVLH WDQGKLRKTG PIFDGLFLPI YEWMQEVSIP
VAKPLVGVHE GYSTLVRDWF EDLREGYSNF FYTGFDTRIE FIRDNGVTTT PLPIKDRPAL
EASRVHSRYA ELGYQGRVVL FMLVTMVTFY FSGPLALLMM LGLVVVGGDS DEPKATFNEK
NRGTTFRDGV YHVANTVIGY ELTNGIGVGF GGVFHVPYHV TRGQSIVYGR TRVYPYYVNP
DQDIVTYGGP PNVVSYQAGD KVFVNCETIQ SRTSYEVQVD VDRMGNVVTW QGVTKPGESG
SPVYAWRDEG MVLLGLAGRY IKEPTGVVEY TNVEPIVRGE SMIEQITSHP GSGKTWKIIP
DIVTKGVMSL NGKKVLVAGP TRVVCRELHK SMQNLGIRVG LNIRGSLDRV EAAPVQIAAH
RTALKMLVTG SPLLRNLGLI VIDEAHMDDT ATKLLRKYAR HLMDMGVRTI ELSATLDGIT
NDGSNHTIND IKIHPTDIEE CIRERLEDGK RVLLFVPSIH GTLATRVARN FKEHKPIRLS
RDTFETAMKE IPDVERQLII STDIAECGIN IPELDTVVDS GEKFTYVMEG NIIIGKKVGL
TLASRTQRRG RVGRTKIGEY IEVASKHDND YISASTFDAD LLAAGRGWAT GKTEWPLTLT
DNQFRKWLDT DLTPLEIYLD YDGSGLERSE NNKRIVHSSI KGGGLNYEGC GKCELCRGAY
YMYDERAHDR IIHGKLRKAV MLN
//
