ID A0A0P0S8L0_9PSEU Unreviewed; 491 AA.
AC A0A0P0S8L0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Transporter {ECO:0000313|EMBL:ALL80294.1};
GN ORFNames=AD017_02075 {ECO:0000313|EMBL:ALL80294.1};
OS Pseudonocardia sp. EC080619-01.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1096856 {ECO:0000313|EMBL:ALL80294.1, ECO:0000313|Proteomes:UP000066228};
RN [1] {ECO:0000313|EMBL:ALL80294.1, ECO:0000313|Proteomes:UP000066228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC080619-01 {ECO:0000313|EMBL:ALL80294.1,
RC ECO:0000313|Proteomes:UP000066228};
RX PubMed=26535611; DOI=10.1021/jacs.5b09794;
RA Van Arnam E.B., Sit C.S.;
RT "A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense.";
RL J. Am. Chem. Soc. 137:14272-14274(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000256|ARBA:ARBA00009843}.
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DR EMBL; CP012184; ALL80294.1; -; Genomic_DNA.
DR RefSeq; WP_060572536.1; NZ_CP012184.1.
DR AlphaFoldDB; A0A0P0S8L0; -.
DR STRING; 1096856.AD017_02075; -.
DR KEGG; pecq:AD017_02075; -.
DR PATRIC; fig|1096856.3.peg.439; -.
DR OrthoDB; 3284414at2; -.
DR Proteomes; UP000066228; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046685; P:response to arsenic-containing substance; IEA:UniProtKB-KW.
DR InterPro; IPR000802; Arsenical_pump_ArsB.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR PANTHER; PTHR43302; TRANSPORTER ARSB-RELATED; 1.
DR PANTHER; PTHR43302:SF5; TRANSPORTER ARSB-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
DR PRINTS; PR00758; ARSENICPUMP.
PE 3: Inferred from homology;
KW Arsenical resistance {ECO:0000256|ARBA:ARBA00022849};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000066228};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..422
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
FT REGION 220..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 47725 MW; 379975754FCA3C7D CRC64;
MSLLLAVALL AVVLVAATVR PFGLPEIVLA APAAVLTVVA GLLTPAAAWA EIAELAPTVG
FLSAILLLGH LADAEGVFRW VGDRLGAASD GSPRRLLVLV FAVAAGTTAV LSLDATVVLL
TPVVLATAAR RGWASRPHSY ACVHLSNSAS GLLPVSNLTN LLAFSASGLG FLGFAGLMAA
PWVAVIVVEY LVLRWYFTRD LLPAPAVPGS GVPGAGSGVP AAGAGAGSGS GVPGAGSGPE
AGSVPDAGSM PETGSAPGSG SGAGSASGGR AGPDSGSRFG SGGDRACAGS GRAPRFALGV
LALTLAGFGA SSAAGIEPGW IAAAGAAVLA VRALVRRETG PFRLVAAASP GFCLFVLALG
VVVAGVSGQG LAGWLGGLLP DTPDLAGLLL TAAIAAVLAN VVNNLPATLV LLAALGPAPS
TGLVLAVLLG VNIGPNLTYA GSLATLLWRR IAAGCGDPPR FTTFAALGAV TVPLGLFAAT
LALWASLTLA G
//
