ID A0A0P0SEQ7_9PSEU Unreviewed; 472 AA.
AC A0A0P0SEQ7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:ALL82886.1};
GN ORFNames=AD017_19910 {ECO:0000313|EMBL:ALL82886.1};
OS Pseudonocardia sp. EC080619-01.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1096856 {ECO:0000313|EMBL:ALL82886.1, ECO:0000313|Proteomes:UP000066228};
RN [1] {ECO:0000313|EMBL:ALL82886.1, ECO:0000313|Proteomes:UP000066228}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC080619-01 {ECO:0000313|EMBL:ALL82886.1,
RC ECO:0000313|Proteomes:UP000066228};
RX PubMed=26535611; DOI=10.1021/jacs.5b09794;
RA Van Arnam E.B., Sit C.S.;
RT "A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense.";
RL J. Am. Chem. Soc. 137:14272-14274(2015).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP012184; ALL82886.1; -; Genomic_DNA.
DR RefSeq; WP_060575095.1; NZ_CP012184.1.
DR AlphaFoldDB; A0A0P0SEQ7; -.
DR STRING; 1096856.AD017_19910; -.
DR KEGG; pecq:AD017_19910; -.
DR PATRIC; fig|1096856.3.peg.4180; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000066228; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07138; ALDH_CddD_SSP0762; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR42804; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42804:SF1; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000066228}.
FT DOMAIN 18..470
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 246
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 472 AA; 48306 MW; 5054F704F034C2B0 CRC64;
MSETTLSHVI GGTSRESAGT DRIEVVDPAT GAPVGSVPAG TAADVDAAVA AARAAFPGWS
ETPVGQRAAV VKAISAGLKE RAGEIADTIT AEMGSPITFS QKVQVAMPIG SSATVAGLAD
GFAWTEEIGN SLVVREPIGV VGAITPWNYP LHQIVAKVAP ALLAGNTVVL KPTEVAPLTA
QILAEVAAAA GLPAGAFNVV HGTGPVVGEA IAAHPDVDMV SFTGSTRAGK RVSVVAADTV
KRVALELGGK SANVVLEDAD LARAVKVGLG NAWINGGQTC TAWTRMLVPA SKQDEIVAQL
VAAAEKYSVG DPTDPSTRIG PMSSAAQQER VRGYVERGVA DGARVVFGGP GPVEGLDGGA
YVRPTIFADV EPDAVIAQEE IFGPVLSVIP YADEEQAVEI ANSTVYGLAG AVFGEQEHAM
AVARRLRTGQ VDVNGGAFNI QAPFGGYKQS GNGRELGRYG LEEFLETKSI QQ
//
