ID A0A0P1ABN9_PLAHL Unreviewed; 376 AA.
AC A0A0P1ABN9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Cysteine protease family {ECO:0000313|EMBL:CEG37801.1};
OS Plasmopara halstedii (Downy mildew of sunflower).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=4781 {ECO:0000313|EMBL:CEG37801.1, ECO:0000313|Proteomes:UP000054928};
RN [1] {ECO:0000313|Proteomes:UP000054928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sharma Rahul, Thines Marco;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CCYD01000291; CEG37801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P1ABN9; -.
DR STRING; 4781.A0A0P1ABN9; -.
DR EnsemblProtists; CEG37801; CEG37801; CEG37801.
DR OMA; HNGEYSE; -.
DR OrthoDB; 5472443at2759; -.
DR Proteomes; UP000054928; Unassembled WGS sequence.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR000169; Pept_cys_AS.
DR InterPro; IPR025660; Pept_his_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF953; CYSTEINE PROTEINASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
DR PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
DR PROSITE; PS00639; THIOL_PROTEASE_HIS; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000313|EMBL:CEG37801.1};
KW Protease {ECO:0000313|EMBL:CEG37801.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054928};
KW Signal {ECO:0000256|SAM:SignalP}; Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..376
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018666647"
FT DOMAIN 40..104
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 132..352
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 376 AA; 41991 MW; C73F401332AC4D63 CRC64;
MKVFGPLYLA TSIVLAPSVA LNSDLPSWLT STEQKTWHEF LNYTLDYEKS YRYDDNNDDL
VLLRFQAFST NLKRIQMHNE AFERGEFTFT LGLNHLADLS DAEYKQLLSY RPRISTSGAS
ETFVKPEDVA DFPDNWDWRD HDIVTPVKNQ GQCGSCWAFS AVAAMESAYA LNTGNLESFS
EQELVDCTLN GIDTCNHGGE MSEGYEEIIK HHNGKIDREE DYPYTAESKG VCNAKDDKAI
GHFTAFGNVT SGDESALLAA VVTKGVQAVA IDASSFTFQL YRHGVYSWPL CGNAPDALDH
GVAVAGYGVY KKKEHWLVKN SWGALWGMKG YIMMSRNKNN QCGIATDASY PLMKKEELLV
SDQATVVETF EIMSVM
//
