ID A0A0P1AQV7_PLAHL Unreviewed; 899 AA.
AC A0A0P1AQV7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
OS Plasmopara halstedii (Downy mildew of sunflower).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=4781 {ECO:0000313|EMBL:CEG43528.1, ECO:0000313|Proteomes:UP000054928};
RN [1] {ECO:0000313|Proteomes:UP000054928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sharma Rahul, Thines Marco;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|RuleBase:RU361221}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361221}.
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DR EMBL; CCYD01000667; CEG43528.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P1AQV7; -.
DR STRING; 4781.A0A0P1AQV7; -.
DR EnsemblProtists; CEG43528; CEG43528; CEG43528.
DR OMA; FARIDHG; -.
DR OrthoDB; 1089019at2759; -.
DR Proteomes; UP000054928; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR11689; CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER; 1.
DR PANTHER; PTHR11689:SF136; H(+)_CL(-) EXCHANGE TRANSPORTER 6; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000054928};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 43..67
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 207..230
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 332..355
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 470..487
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 529..553
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 782..839
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 899 AA; 100565 MW; 8FA63AFE11C6C477 CRC64;
MLWNSSDLES LDYDLFESVV NKSGMGYKYR NGQEKNRLIY ARWFLTLATG VITALVAVFM
LYFTMLLMSL RQHLLEYTIH RELSKHVLFG TTFWSIVLFN LVLVGISATI TSFGEMVAAG
SGISEVKTTL NGMKIPRMLR LRTFVCKVIG TVCSVAGGLP VGKEGPMIHS GAIVAAGLSQ
GKSSTLGYDT SFSYFAGFRN DREKRDFVAC GAAAGVASAF GAPIGGVLFV LEEGASFWNQ
SLTWRTLFCA MSATFTLAFF LSGMNDNLSW GTLGSHTGSF SFGPFASSTY QIWEVPLFVL
MGVGGGLQGA FFNGLNTRLA RLRSRWIRTR GVAWAEALLV SVLISSLLFS TPFLLGKCHD
LPKVREDVVH LANVASATAA PSKTFVFGME MLKKNGSACI CESCTSVSID GAECFQADET
VQYPYKKELV RFYCPEGQYN DLASLMLTGG EAAIKHLFHA PPDSFDVRNL VVFWLLMLML
ACITYGLKIP SGLFVPALLI GAAYGRLWTR VINYFTGLHH LKTVDPRTYG LVGSLAMLGG
VTRMTISLTV IILECTGNVE FGLPLILTSF FARWVGNYFN EGIYDIHIHL RHVPFLDWNP
PLRGAFLRVK HIMTANPKTL RTVERAGVIF DLLVSTKHNA FPVIVEDPTF GTHFFAGIIL
RKQLNVLLSH HDFSIEKPKP FTRQPHPASY RSDVSLTGHL RHRRSKDIET EQTPRIDDQL
LESPSANNYC LSYHDMENHY PRYPIPTPMH HNFQHVDRTA GDEIYTLLEE DRALWVDLTP
YINQTPYLIQ EEAPFVRAYR LFRSAGLRHL VVVNRHNNVR GIITRRELEE KHCTRCFRLA
KNIDADDVYP LSGAPPVGFF RKLRRTISRT EQVKRALSIS VSNVRDNDVN NDNGTLLRP
//
