ID   A0A0P1AR25_PLAHL        Unreviewed;      1134 AA.
AC   A0A0P1AR25;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Calmodulin and related proteins (EF-Hand superfamily) {ECO:0000313|EMBL:CEG44058.1};
OS   Plasmopara halstedii (Downy mildew of sunflower).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=4781 {ECO:0000313|EMBL:CEG44058.1, ECO:0000313|Proteomes:UP000054928};
RN   [1] {ECO:0000313|Proteomes:UP000054928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sharma Rahul, Thines Marco;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CCYD01000810; CEG44058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0P1AR25; -.
DR   STRING; 4781.A0A0P1AR25; -.
DR   EnsemblProtists; CEG44058; CEG44058; CEG44058.
DR   OMA; NLCEKRS; -.
DR   OrthoDB; 70957at2759; -.
DR   Proteomes; UP000054928; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 4.
DR   Gene3D; 1.10.238.10; EF-hand; 6.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   PANTHER; PTHR20875; EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED; 1.
DR   PANTHER; PTHR20875:SF9; EF-HAND DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13499; EF-hand_7; 6.
DR   SMART; SM00054; EFh; 12.
DR   SUPFAM; SSF47473; EF-hand; 5.
DR   PROSITE; PS00018; EF_HAND_1; 6.
DR   PROSITE; PS50222; EF_HAND_2; 10.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054928}.
FT   DOMAIN          43..78
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          171..206
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          213..240
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          311..346
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          665..700
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          824..859
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          935..969
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          970..1005
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          1045..1080
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          1081..1114
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          569..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          761..804
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..23
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        591..610
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        611..626
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        761..781
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        788..804
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1134 AA;  129211 MW;  0D2F18ED34958695 CRC64;
     MLRSQLSQST VMTSASEKLQ AGSTPTHARD LHRKLLERVL LRSDTKSVKD VFRRYDRERA
     GVLTLQQFRA LVRDHDFSDT DADLLLHHLD VQEQSVSFHA FMGEELLSVE QNYSSRKSNS
     PKKVQQLAQF PEQKKVLSNK KANKVAVHSD TLAVQDPMEA IRTKLRQRVM GHDKSIREIF
     MEYDSDGSGF LDYEEFDRFM AKYGFAPSET KIIIDYLDRD HSGTVDYDEF ASGLLFYRPP
     LPISIAPAQT VALPLSLTTI ENAQKMQRQI GLDLSRRDDK KICKEADIQQ ILETVQNKFK
     DVFRRSKQPT DGFVELRAEF DRFDVDGSKS LDHQEFGALL IGIGIKLKVA ELSALLQVID
     PDGEEKIQFY TIKRLLCFQE PSNRGLEQQQ SGPMKFDSEN IVKSANYVCE GVEEQEKDRL
     RRLQYENSVG IDRKINIMNE NLDGDKRAVT NYSRFAQEFS DQVEPSVDLP PRSQAFNGLY
     NFHENGKADL NDIRQHLNGY DSKKIDAVDS LHVQTKFDEN GAISLQEATH GFAQTEKPSR
     TPDSDEVAIS KKLKDYLGQA KLNEFGRMMQ GSTNNINGRT EDKDDINSGS FEESTRVYDL
     SRGSAHKTTS LRQSPDRRTE GIGLDDSRLD KKMRQTLQVS PNINKMGRLA AQQDQEMQFM
     ERVLERHHSI ESAFREFDPD VQNKLNFEQV GAFMARYGMT DKEHISMLLK RLDINNSGTI
     KLQDFLSVFD VRRLALIEGE STRHEEKNLK GLAQNEGKIT KSGARDGKYQ KNGENRVSPH
     VIKRGAKLGT TSNPSASDTK ATNRSANVAR LRKLEEKWIR RALARHELLS SVFDIADHDK
     DGKITRDEFR KLMNLYGVQD EEDVVALMKK LGVDGDGCIN YKDFAKTFNE TRVANFTAST
     PEVIISPTAS PIDTKHAQGA RLQGLQIKWI KRVLSCHDSI ESAFYQYDKD GSGELNHEEF
     HYFMTRYGIV RNEDISALIR RLDTDGSGTI SLKEFSLIFN SLRVSSGMTN EGMRTIAAGL
     EEITDPEEIE SILEIERELA QRMAHQTRDL RLAFRKIDTN GNGLLEYKEF RTVLKLYRLP
     EMEIRKVIRH LDRNVSGFID YKQFVAGFSA FKENGSSVPA AQKKKVKLRS PQKG
//