ID A0A0P1AUH8_PLAHL Unreviewed; 475 AA.
AC A0A0P1AUH8;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Trna-dihydrouridine synthase {ECO:0000313|EMBL:CEG45271.1};
OS Plasmopara halstedii (Downy mildew of sunflower).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=4781 {ECO:0000313|EMBL:CEG45271.1, ECO:0000313|Proteomes:UP000054928};
RN [1] {ECO:0000313|Proteomes:UP000054928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sharma Rahul, Thines Marco;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR EMBL; CCYD01001551; CEG45271.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P1AUH8; -.
DR STRING; 4781.A0A0P1AUH8; -.
DR EnsemblProtists; CEG45271; CEG45271; CEG45271.
DR OMA; QDVKLHY; -.
DR OrthoDB; 276273at2759; -.
DR Proteomes; UP000054928; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0017150; F:tRNA dihydrouridine synthase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd02801; DUS_like_FMN; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR035587; DUS-like_FMN-bd.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR018517; tRNA_hU_synthase_CS.
DR InterPro; IPR022755; Znf_C2H2_jaz.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR PANTHER; PTHR45936; TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE; 1.
DR PANTHER; PTHR45936:SF1; TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE; 1.
DR Pfam; PF01207; Dus; 1.
DR Pfam; PF12171; zf-C2H2_jaz; 1.
DR SMART; SM00451; ZnF_U1; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR PROSITE; PS01136; UPF0034; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054928};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 382..416
FT /note="U1-type"
FT /evidence="ECO:0000259|SMART:SM00451"
FT REGION 432..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..450
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..469
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 52920 MW; E540CD9B3950E0B0 CRC64;
MSELYENKVC LSPMVRSGTL PLRLLSLRYG ADLVYGEEII DKRIISSIRV PNEVVNAVDF
VSRNGDSVVF RTCSEESKKI VFQIGTADAV LALKAAEMVA RDVVAVDINM GCPKHFSIQG
GMGAALLKKP EVACDIMKSL RRNLNIPVSC KIRLLSETQD TIDLAKRLEH AGACAIGVHM
RQVHERPRDK ASWDRLAPIV SALSVPVLAN GDVFAYEDMK KLRAISGVSS FLIARGALAN
ASIFRENGRL PVDQVVREYL MAAAEVDNVF QNTKYNVMRM IPNSHADAYA SENNYGYGKN
ARVVTVSELA ATKNPLQMYS LWDLQNCYLQ CQDQFRVKAA AVKEKENLQD QILRNSAISP
PTENHHGNDS KDIEFHDNLM SKPELYCVAC KKQLLSEQDV KLHLKGRKHK KVLSRQASAT
FSKVYAKTQL EQNLPTSDAT QSSNTDSGGM EFRQCEEESK RDFKRSKLED SVTIA
//
