ID   A0A0P1AVZ9_PLAHL        Unreviewed;      1581 AA.
AC   A0A0P1AVZ9;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=5-3 exoribonuclease 1 {ECO:0000313|EMBL:CEG46399.1};
OS   Plasmopara halstedii (Downy mildew of sunflower).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=4781 {ECO:0000313|EMBL:CEG46399.1, ECO:0000313|Proteomes:UP000054928};
RN   [1] {ECO:0000313|Proteomes:UP000054928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Sharma Rahul, Thines Marco;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CCYD01002047; CEG46399.1; -; Genomic_DNA.
DR   STRING; 4781.A0A0P1AVZ9; -.
DR   EnsemblProtists; CEG46399; CEG46399; CEG46399.
DR   OMA; VASWPWF; -.
DR   OrthoDB; 167745at2759; -.
DR   Proteomes; UP000054928; Unassembled WGS sequence.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18673; PIN_XRN1-2-like; 1.
DR   Gene3D; 1.25.40.1050; -; 1.
DR   Gene3D; 2.170.260.40; -; 1.
DR   Gene3D; 2.30.30.750; -; 1.
DR   Gene3D; 3.40.50.12390; -; 2.
DR   InterPro; IPR027073; 5_3_exoribonuclease.
DR   InterPro; IPR041385; SH3_12.
DR   InterPro; IPR040992; XRN1_D1.
DR   InterPro; IPR047007; XRN1_D1_sf.
DR   InterPro; IPR041106; XRN1_D2_D3.
DR   InterPro; IPR041412; Xrn1_helical.
DR   InterPro; IPR004859; Xrn1_N.
DR   InterPro; IPR047008; XRN1_SH3_sf.
DR   PANTHER; PTHR12341:SF41; 5'-3' EXORIBONUCLEASE 1; 1.
DR   PANTHER; PTHR12341; 5'->3' EXORIBONUCLEASE; 1.
DR   Pfam; PF18129; SH3_12; 1.
DR   Pfam; PF18332; XRN1_D1; 1.
DR   Pfam; PF18334; XRN1_D2_D3; 2.
DR   Pfam; PF17846; XRN_M; 1.
DR   Pfam; PF03159; XRN_N; 1.
PE   4: Predicted;
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054928}.
FT   DOMAIN          1..239
FT                   /note="Xrn1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03159"
FT   DOMAIN          282..635
FT                   /note="Xrn1 helical"
FT                   /evidence="ECO:0000259|Pfam:PF17846"
FT   DOMAIN          693..891
FT                   /note="5'-3' exoribonuclease 1 D1"
FT                   /evidence="ECO:0000259|Pfam:PF18332"
FT   DOMAIN          896..996
FT                   /note="Exoribonuclease Xrn1 D2/D3"
FT                   /evidence="ECO:0000259|Pfam:PF18334"
FT   DOMAIN          1052..1158
FT                   /note="Exoribonuclease Xrn1 D2/D3"
FT                   /evidence="ECO:0000259|Pfam:PF18334"
FT   DOMAIN          1202..1265
FT                   /note="5'-3' exoribonuclease 1 SH3-like"
FT                   /evidence="ECO:0000259|Pfam:PF18129"
FT   REGION          1547..1581
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1581 AA;  176506 MW;  EFD646A9101FDC03 CRC64;
     MGIPRFYRYM SERYPLINQP ISDVSLLPEF DAFYLDMNGI IHNCTHSDSA DDALNSLTLE
     AQLHGIFTYL DRLITHIIKP KKIVYIAIDG VAPRAKLNQQ RSRRFRAGLE RQEAIDKEKH
     MQIKLQDEKN GTVMKPTASK FDSNCITPGT EFLSQLSHHL VYFVRQKMKN DPLWARLEVF
     FSGSEVPGEG EHKIVEFIRH RKMTVDYEAN MRHCMYGSDA DLMLLGLMTH EPHFTLVRET
     VVWGSFHKKV AVKKIEEQQW QLVHLSLFRE YLMLEMNVQP PFDGERMIDD FILLTFLLGN
     DFIPHSPTLE ISEDAIPLLL KVYRDLLELH QGCYLTLNGK IRNAKLLQEL FQIIGNQEEE
     ILVNRAMEEK RRSGRRGGRQ QSKQHEVDAA EMQSAIMALR DADEETLPPL VNDEDIDDEE
     AERLLLEALD GKDDTIFSLE LQREDQNILM LVGSESFQDT KWNYYERKYN IQRGNDDASN
     DALEQVRKSY IEALVWCLAY YFQGPPSWAW YYPYHYAPMV SDLTNIENMI TSVTFDDDPL
     IAGPLLPFEQ LMSNLPASSA HLVPEPYRFL MVSPLSPIKH FYPETFDIDM EGKRNAWEGV
     NLLPFIDVGL LKQAIAQYCP DSRLTEAERR RNKLQLLPVR IVRDLNALDT LKSPLPGVAD
     LQYCNTRVED FKLPPIPGGE FQSKLMDGVV LPLAGFPSLN TASLETTRIA SVGLNCFGMS
     SRKSSLILQL SASGSINDSD NTNADNINPR DLLGTSVLAN WPNLHEVLVV GISTLSGEYR
     LSKSTRQLNN HPKDRTEIVY TPYGSDEKSA WAYYAQMEAV KLLSGRGVPG SGGIDLGKTG
     ITIVMHVLPL QGMVSNSISG AIEKKFGETE AFVPAQLTVR NLKLLDARFK ETGTLPLIDR
     FPIDSKALIT SGKWLGCTAI VQSIDELQHA VTVQVQTIDQ EPPFGYVIAQ KVTDHYYPGN
     LVAQKLGLVA STLGILTGSV LVKPFGVDIG LNLRYRKELL LPGYCRLVSR DSIDSDIKDD
     TNIWRKGDIV KIVGTRSIDS DLSSSRAQND SITTWEYTER AIQLIASYQK EFPEVVRNLS
     QLPFATSYRG KDVFGISDSK QVAVMAEAVK QWIEEQHLGA SEHFKHIPVT SKYIALNAVR
     AMEAAGTLRV KERTKSSEVQ RCAPVVETVR AADLFRPNPL VNQDLTGHEV SLRSSLNKGA
     PNLGDRVINI SARGVPFGHR GTVVATHVSS RCVEVLFDES FTGGEPLYGT LSLDRGKIVA
     WSNLLCVSFP SASHFHAMKH KPARQSQTTI TATQQRTTGD IPVVSTNNSI RPKKLANKPL
     AVTVASASLV PPPPPIPSAL PSPPNPHNIQ KLIQKWSFDG EVATQESILM SAESAPLASK
     PKAKEELAPS VAALFSSIQN GTPSSTPTPV GPVMNLFPHL CAQTTPIAPS LLTPPLPKGA
     PTPQYMTQQS SMYQPPTFSM PGQQAHLILM PDGSYVPMYA PLPSAYIQSQ PPMPRSDDRY
     LQSAVPLSKY DKNLTAVGAW KQKPSIRGDK HRKNTYAATA SNIAVTNANK NHKEWKPKQK
     SAAKSPQLLL PAQVMRHQKP Q
//