ID A0A0P1B2V4_PLAHL Unreviewed; 2680 AA.
AC A0A0P1B2V4;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Kinase A-anchor protein Neurobeachin and related BEACH and WD40 repeat proteins {ECO:0000313|EMBL:CEG48382.1};
OS Plasmopara halstedii (Downy mildew of sunflower).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=4781 {ECO:0000313|EMBL:CEG48382.1, ECO:0000313|Proteomes:UP000054928};
RN [1] {ECO:0000313|Proteomes:UP000054928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Sharma Rahul, Thines Marco;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CCYD01002939; CEG48382.1; -; Genomic_DNA.
DR STRING; 4781.A0A0P1B2V4; -.
DR EnsemblProtists; CEG48382; CEG48382; CEG48382.
DR OMA; CPWLLEI; -.
DR OrthoDB; 48429at2759; -.
DR Proteomes; UP000054928; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13743:SF112; BEACH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CEG48382.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054928};
KW Transferase {ECO:0000313|EMBL:CEG48382.1};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 1681..1809
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 1820..2111
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REGION 2117..2144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2128..2144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2680 AA; 299990 MW; 50AB26191A80F367 CRC64;
MQQPLPALQD NRSISTETDI NSHLVAETLA SSNENPAEMI SLSPSKAAHE LVRKAMLACF
MDCSSSERSQ LLQDVQTLSR QFAKHLFLPT NESSREEDEN QSQYVLPREQ VAPPSAFYCF
HHNSRMYLPI IDWSAFRGFS VAMWINVDFY RPRTKKDEDL CAKFYLFRFT NGSNTLGIEA
SVEFTDNSSD NMLLNFSCGA AGTGIESKKS ASIATSSLKT LEWRRIQHKV KLRRNRWHLL
VLSHSLHYVK KSKVTCYVDK KLQFTDELVY PSGLVTASKC TIGGGRNASA KVASVTMYQE
EMPRDTIELI YGLGPSVSSF NRWTAVPAPS NRTVASTVLG QSSLRIPENE AFTAFWKLQV
VFAFNAQNVV NEDYADLGVE WLCEGTSPKQ SGKWLTLETT LGISSEIQQR TARLGKNTQK
KIFADFSAAW YRCAGISSLP VLLDYVCTAY EKTIRASNSS EMTTTRPLSL VLESLVVDFL
WICKGILLSS VNNQQEVVRN YVFHLFSHVL VKHSRCLSVI WTPGSLVVCV EMVKSLAQLM
PMSKRSSNVG ENHPIHPSIW ATNPLFSAGV RALLLDYRLW SHADYKTQSI YNHQLYGLAC
EYPRAFNNLR AVTKVLEILN VFYSTSSSSH SSNDTKLSQN SHQLTALNDT NHHWKQQCIQ
TLVEVIEVCL TNQSTHVHEV LEQELMETTF ARASSSAGNG TTGGVFSINL ECITWSDQAG
NSVDTEEKGS KMSVLHSIQV RFSLVRDIRA VIRFLLTSKD AAVCTSLLLL LRRLAVSFRD
MRFALISSCV MDCLLYLMQD RRTDADRTTH SHLSIHVRMA CVPLFIYLLD WLESIEGRTV
WCGLEEHLRL VLNAHSNFSV GFVELMVEFY FDPAWLLGVQ HSIIMNDPSK KDSLLFPIAS
SASTKVLVSK EKGRHDGIAV EMSPDTGEPN SGIGGLMEWI KLTAPFTGKR LQLTWEKRAS
VIRLMALRNL SNVGEQSPAI IAESFDEGVS GILSLPLTGI LPFLPILLGN GTPHFREKVL
MDINVKLKTD EDVQQLVLSM NKRWAEALLE LSLTCSIGVE TVRDCSQEEL DGCGRAYSID
ASKTGEDLVL DTIVSLLCMA MENSRGWSSF THLLVALRNI QLKYESEFSA STLSSLPPLT
QVSSFVHKSE IFCQPFNWLC RVVGIVLQRM ARSRTILSRT LAENIQRVLF LVHETLLTLP
VVGSDKYAWS DAQLFLLNSV LEVCTRLVQS THKLHRVGLC PGLEILQCAL PYVTAKTMME
RVVNLLVQIF QQELTVGAAL RVYESMPTRD VFLHALVDLR RALVIHKKEE LLSLLRGLTL
RICTSGSFDG ELDGAGLSSY ELSALTEQKA VEVVLDTLAL AINDKESHER EDEGDRVPYF
PVARELRTLQ PDTRYQSHKC SSAESKDESE RVLWAALEVE ENRMLATLRD VTSREMQRVL
TTTSVQRDQK FKWTQELWMK HEFIFRSQHE YDAFKHKAPA TLEILQKTHV WRLGAYESPF
PSRVRRTLDV DLYLSAEKML TMQSSGRDDV EEVEPAVLKP RQPSGSVVSL EKMSYCLEMG
DNVDDACISN EVIGGSLLER VGRVVAQQRG GEIQDITTDD AQFVDTYVPI TDAEDKETEA
QNEPLDDLLD EYKLDTIPTV NMETNGANMS TNASAGSSIK GMAFSGQEDE GLDPGAGIAV
APGDRVYASI TCRRVVPEGI VQGRLSLCTR HIVFEPQPDR SEQTVPRDSI TNFDDTTLSA
WSNSSVDEVA PGLHRCWRWK YRHLVGVYLR RYRLRDSAIE LFLRSGISHF LDFPRTTKHR
RNEFVRVLYS FLPRSTPKQW PGQVIPHLAA TTKAWQNGQI SNFDYLMALN TYAGRSFNDL
TQYPVFPWVL SNYHDATLDL SDSQNFRDLS KPVGALNASR LDEYWERYHS FDDPVIPKFL
YGSHYSTCAG VVLFFLFRVE PFATLHQKMQ GGTFDLPDRL FFCMEETWRM CNSHMSEVKE
LTPEFYASDG TFLRNGNRYA LGKRHDDKAV DDVQLPPWAA TPEDFIRIHR AALESEYVSS
HLHLWIDLIF GNKQRGRASL EANNVFYYLT YYGVVDLDKV DDPFLRESME LQIAHFGQCP
MQLFATPHPK RLTSIRRSAG APAAPVSERQ SPTASDGNLS GLSSSVPRPL SVAFQDFSLI
AQERRRHWSP LASVKPIAQS GIRLLKILPD RVVSINELGV VEVYYWKLLS KPVSPSSSIV
GSLSPHVKTI ASDFSDSTDV SRNSFSSVTS LPRESEEETL LSDLAVCEDN GEKFLTECPW
LLEIVRDDSP FDYVPRIPVF DLVASDRHNH LNQRSCGFPV VMTGNGRVVV SGGARNGALH
FRLLDLDNGH VIGKASVVGH SAAVTCLSRD RANSHGPHYI GVSSVHEDDE VVVSGSQDGT
LALWRLSRLK PDLLFRLPRV SPCPIQLFRG HATRLVDCCV STYLNLIVSC TQDVGMVHYI
HEEGQVAFVF RPAESNGEFV RVCLSIKGYI LAITSVKQSQ NEERPLVSSI YQLFSMSGVL
IQTHCLSGEE IVDIQVAAEG DLVFLTLVSG IIRICRIEDF VTVQEYISPT SNGSMISATC
FGPKEAVILL ASGHKDGTLS LQLLPDASGS VSFLTNVRRL FGVSSKLKRV KGTVQHAQTL
AMSTLDNAKA VTNTARDIAG EAIGEAKVMM RGLISYLQKG
//
