ID A0A0P1BGY5_9BASI Unreviewed; 449 AA.
AC A0A0P1BGY5;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=mRNA m(6)A methyltransferase {ECO:0000256|ARBA:ARBA00012160};
DE EC=2.1.1.348 {ECO:0000256|ARBA:ARBA00012160};
OS Ceraceosorus bombacis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Exobasidiomycetes; Ceraceosorales; Ceraceosoraceae; Ceraceosorus.
OX NCBI_TaxID=401625 {ECO:0000313|EMBL:CEH15412.1, ECO:0000313|Proteomes:UP000054845};
RN [1] {ECO:0000313|EMBL:CEH15412.1, ECO:0000313|Proteomes:UP000054845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Magalhaes I.L.F., Oliveira U., Santos F.R., Vidigal T.H.D.A.,
RA Brescovit A.D., Santos A.J.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-
CC methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:55584, Rhea:RHEA-COMP:12414, Rhea:RHEA-COMP:12417,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:74411, ChEBI:CHEBI:74449; EC=2.1.1.348;
CC Evidence={ECO:0000256|ARBA:ARBA00036277};
CC -!- SIMILARITY: Belongs to the MT-A70-like family. {ECO:0000256|PROSITE-
CC ProRule:PRU00489}.
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DR EMBL; CCYA01000264; CEH15412.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P1BGY5; -.
DR STRING; 401625.A0A0P1BGY5; -.
DR OrthoDB; 179166at2759; -.
DR Proteomes; UP000054845; Unassembled WGS sequence.
DR GO; GO:0001734; F:mRNA (N6-adenosine)-methyltransferase activity; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR007757; MT-A70-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12829; N6-ADENOSINE-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12829:SF2; N6-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT; 1.
DR Pfam; PF05063; MT-A70; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51143; MT_A70; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CEH15412.1}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054845};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 449 AA; 49822 MW; 115AC1B7C1188055 CRC64;
MSTEHAKAVQ EISSLYLRPR TAKTRLLSEL LSAPDTRHQE ICQHLTLADC AAALSWQSGH
EEVSGEALTC QSVHFEVVMY PQTDLSYGHC SYLNTCHRTT TCKYLHFRPV RSSDASPFAW
HSKLREPCPQ VYDSANPGVS PTSRAAVLQG LASGENESGS EAATQLFETA SVRHPLHALQ
QVGAHTWYGG GGGDGGRGAA SEAAPPVQLP PQWMDVDLRD FDYSMLGKVD VILADPPWDI
HMSLPYGTMT DDQMRSMPLA QLQDEGFIFL WVTGRAMELG RELLAMWGYA RVDELVWVKV
GQTQRLIRTG RTGHWLNHTK EHCLVGAKRQ PLRDLEETPQ LASPLSNLSQ IYPAAQPAGA
RSAVPSWAHA GLGADVIVSE VRDTSRKPDE LYGLIERLCP GGRKIELFGR KHNARPGWIT
LGNQLKSDRL YDQELLEKLN TWRAGKWIT
//
