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Database: UniProt
Entry: A0A0P1FCB7_9RHOB
LinkDB: A0A0P1FCB7_9RHOB
Original site: A0A0P1FCB7_9RHOB 
ID   A0A0P1FCB7_9RHOB        Unreviewed;       694 AA.
AC   A0A0P1FCB7;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   08-MAY-2019, entry version 19.
DE   SubName: Full=Fatty acid oxidation complex subunit alpha {ECO:0000313|EMBL:CUH52567.1};
GN   Name=fadB_1 {ECO:0000313|EMBL:CUH52567.1};
GN   ORFNames=SHM7688_02014 {ECO:0000313|EMBL:CUH52567.1};
OS   Shimia marina.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae.
OX   NCBI_TaxID=321267 {ECO:0000313|EMBL:CUH52567.1, ECO:0000313|Proteomes:UP000054823};
RN   [1] {ECO:0000313|EMBL:CUH52567.1, ECO:0000313|Proteomes:UP000054823}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 7688 {ECO:0000313|EMBL:CUH52567.1,
RC   ECO:0000313|Proteomes:UP000054823};
RG   Swine Surveillance;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+)
CC         + NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57318, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|SAAS:SAAS01123908};
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00324886}.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC       {ECO:0000256|RuleBase:RU003707}.
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DR   EMBL; CYPW01000018; CUH52567.1; -; Genomic_DNA.
DR   RefSeq; WP_058239781.1; NZ_CYPW01000018.1.
DR   EnsemblBacteria; CUH52567; CUH52567; SHM7688_02014.
DR   OrthoDB; 977512at2; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000054823; Unassembled WGS sequence.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 2.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000054823};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00324839};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00324863};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00331296};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054823}.
FT   DOMAIN      292    467       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      472    566       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   DOMAIN      600    684       3HCDH. {ECO:0000259|Pfam:PF00725}.
SQ   SEQUENCE   694 AA;  73068 MW;  F2A53533D79CF9E2 CRC64;
     MSDKKVRVEI VEEVALICID NPPVNASGLA VRQGIVAALE EISAAGSIGA VGLYCAGRTF
     IAGADITEFG KPLQEPGLPG VCDTLENFDT PIVAVIHGTA LGGGLETAMG CHARVALPSA
     KVGLPEVLLG ILPGAGGTQR APRLAGIPNA LDLILSGRHV AAQEALEMGV IDRIMEGTPR
     DVALAAAREV VAGTLATRRT GTLQTAPDDA AIATTLAHVQ QKHPQLISPQ KCVECVAAST
     GDLQEGLAFE RAAFMECLAS PQSKALIYAF FGERAVANIP EKTAQARDIG SLGVIGGGTM
     GSGISTAALM AGLPVTLIEV TQEALARGVA TITSNLEGAV KRGKMGAAAR DAALARLTAS
     TEMQSLSEVD LVVEAVFENM EIKKEIFGKL DGICKEGAVL ASNTSYLDIN EIAAMTGRPQ
     DVLGLHFFSP AHIMKLLEVV AGENTAPQVV ATGFALAKKL RKVAVRAGVC DGFIGNRILG
     YYLKAASYLV LDGAHPDQVD RALEGFGFAM GPHRVGDLAG LDIGYMTRKR LAATRPPEER
     YSGAIADQLS ENGWNGRKSG KGYFVYDGRE TLENPDLNAI IAEARAKAGI TPRDFSVAEI
     VERYMTAMIS EAARVVEDGI ALRPVDVDVV FLMGYGFPRF RGGPLHYADT IGAAELVRRI
     EAYAEEDAHY WQVPDLLRKM AADGTTFADL NKGK
//
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