ID   A0A0P1GZM9_9RHOB        Unreviewed;       946 AA.
AC   A0A0P1GZM9;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Tetrathionate reductase subunit A {ECO:0000313|EMBL:CUH88218.1};
DE            EC=1.8.-.- {ECO:0000313|EMBL:CUH88218.1};
GN   Name=ttrA {ECO:0000313|EMBL:CUH88218.1};
GN   ORFNames=PH5382_02151 {ECO:0000313|EMBL:CUH88218.1};
OS   Phaeobacter sp. CECT 5382.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Phaeobacter.
OX   NCBI_TaxID=1712645 {ECO:0000313|EMBL:CUH88218.1, ECO:0000313|Proteomes:UP000050782};
RN   [1] {ECO:0000313|EMBL:CUH88218.1, ECO:0000313|Proteomes:UP000050782}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 5382 {ECO:0000313|EMBL:CUH88218.1,
RC   ECO:0000313|Proteomes:UP000050782};
RG   Swine Surveillance;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; CYSG01000008; CUH88218.1; -; Genomic_DNA.
DR   RefSeq; WP_058334349.1; NZ_CYSG01000008.1.
DR   AlphaFoldDB; A0A0P1GZM9; -.
DR   STRING; 1712645.PH5382_02151; -.
DR   OrthoDB; 9810782at2; -.
DR   Proteomes; UP000050782; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02783; MopB_CT_2; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.30.200.210; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR   PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR   Pfam; PF04879; Molybdop_Fe4S4; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SMART; SM00926; Molybdop_Fe4S4; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:CUH88218.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050782}.
FT   DOMAIN          16..77
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
FT   REGION          917..946
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   946 AA;  105313 MW;  10BEA1118B725147 CRC64;
     MTFQQPRVET SPKVSDEIRQ TTCYMCACRC GINVHMKTNE DGKKEVAYIE GNRDHPVNKG
     VLCAKGSAGI MQVNAPSRLK APLKRVGPRG SGEFEEISWD EALEIAAGWL EPIRKDDPSK
     LAFFTGRDQS QSFTSFWAQN FGTPNYAAHG GFCSVNMAAA GIYTMGGAFW EFGQPDWDYT
     KLFLLFGVAE DHDSNPIKMG LGKIKARGAR VIGVNPIRSG YNAIADDWVG ITPGTDGLFI
     LSLVHVLMKA GKIDLDYLSR FTNAPVLVNQ DPNSPDKGLF LRDDHGAPLV INRKTGKLAP
     FDMAGVRPDL GGSFQMGDVT HVSVFQLMAE RYLKDEYAPE AVAERCGIPA KRIRAIASEI
     ARVAFDEAFE LDQEWTDFRG EKHDKMIGRP VSFHSMRGVS AHANGFQTCR ALHVLQILLG
     TVEAPGGFRF KPPYPKPVEA HPAPHSRVTP NKPLDGPHLG FVHGPEHLAL KSDGSAARID
     KAFTWENPMS SHGLMHMVIS NAHAGDPYKI DTLFMYMANM SWNSSMNTTG VMEMLTDKGE
     DGEYKIPRII YSDAYSSEMV AYADLVLPDT TYLERHDCIS MLDRPICEAD GAADAIRWPV
     IEPDRDVRGF QTVLVQLANK MKLPGFTAED GSAKWQDYAD YIVNHERKPG IGPLAGFRGP
     NGDKAGRGEV NPEQLDRYIK NGGFFVEHIP TEASYFKPWN MAYQDWAVNL GLFDSPQPYL
     FQLYVEPMRK FQLAAEGHGE RQPPDHLRDR IKDTMDPLPI WYETDQQGNE GFTVNALTQR
     PMAMYHSWGT QNAWLRQLHG HNPLYVPTKL MRENDLQDGD WAKVTSPHGS ITVPVMEMAA
     LNNNTVWTWN AIGKRKGTWA LEENAPEATK GFLLNHLIHE LLPPKGDGMR WANSDPITGQ
     AAWFDLKVKI EKAGAPDDFN ESQPVLEPIK SPVGTGPKDL KWKVGK
//