ID A0A0P1H0X1_9RHOB Unreviewed; 909 AA.
AC A0A0P1H0X1;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=luxQ_3 {ECO:0000313|EMBL:CUH83703.1};
GN ORFNames=TM5383_00903 {ECO:0000313|EMBL:CUH83703.1};
OS Thalassovita mediterranea.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Thalassovita.
OX NCBI_TaxID=340021 {ECO:0000313|EMBL:CUH83703.1, ECO:0000313|Proteomes:UP000051681};
RN [1] {ECO:0000313|EMBL:CUH83703.1, ECO:0000313|Proteomes:UP000051681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 8383 {ECO:0000313|EMBL:CUH83703.1,
RC ECO:0000313|Proteomes:UP000051681};
RG Swine Surveillance;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CYSF01000006; CUH83703.1; -; Genomic_DNA.
DR RefSeq; WP_058317846.1; NZ_FTNX01000001.1.
DR AlphaFoldDB; A0A0P1H0X1; -.
DR STRING; 340021.TM5383_00903; -.
DR OrthoDB; 9801651at2; -.
DR Proteomes; UP000051681; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.20.120.160; HPT domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43047:SF79; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF01627; Hpt; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47226; Histidine-containing phosphotransfer domain, HPT domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:CUH83703.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000051681};
KW Transferase {ECO:0000313|EMBL:CUH83703.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 265..336
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 412..630
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 657..774
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 706
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 909 AA; 100549 MW; B12086554D5C10D7 CRC64;
MPIEPHTDSI ETPPKRGIAR LWGAVSKRFA RAHAPFTGQQ FSDEELYAVH PTSTQRVIGN
PRLLALLSVV GFIVMTTLTM QVVRDVRLLR QSTIEDIEWS LSKAEVEFLS YQYALRQAAH
GRVDNFVTLR REFDILQNRI EDLRFGVIYE PLRDVPGFNA ALDSVSQHLG ASAPALRSVD
ATLARSLIEV EEHALAMTPH VRAMAAAGQT NLEILFDRHQ MALSTTLQVM GAVGFILTAS
LGLLAFYFNQ LRQQSDARRR SLITAGERTR AVMASSLDAV IVCDPEGVIE EFNAAAEEIF
GHRREDAIGA NVADLIVPAE QREAHVRGMR RVSRGGGFHM VGKGRVRMEA RRADDTMFPI
EMALQKSESH GHMMYIAFVR DISYRVRAER DLIEARDQAR AGEKAKSRFL AVMSHEIRTP
MNGILGNMSL LRETKLSPEQ EGYLAHMESS SDILLGHVND VLDIARCEDG KPVVQYRPTR
LRDIIDSAVE SMRPPAEDNG NSLTLIHSGP DLGWVQTDPG RVQQMLLNLL SNAAKFTENG
SIIVDVRCKA QEDDITIHIK DDGIGIAEPD LDRVFEDFFT QDDSFARKTE GTGLGLGIVR
RISEALGGSV SVTSKLGIGT TFTLRLPMPR CAAPEDVTPP EPKVSDAMEQ NTTDMLRILV
VEDNQINRDV VRAMLTREGH LVEEAHNGQS GVEKASEKEF DLILMDISMP VLDGREATRA
IRDGEGASAN SPIIALTAHV MPENVTEFLG LGMQDVLPKP LLRPDLQRII RDHAAAANND
TCPTTVRMNQ MRQLVDMEVN KALRESVGEA YDMLLGQMSE ELQDLLEWLQ AAEQPLPEVA
DRCHKFASSA AVFGALPLQK LLVGIELAAK SRDTVEVERR LAQLPEMLAT SLNHLQGGGM
GHNQGRKRG
//
