ID   A0A0P1IQT3_9RHOB        Unreviewed;       805 AA.
AC   A0A0P1IQT3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:CUJ95584.1};
DE            EC=2.1.2.10 {ECO:0000313|EMBL:CUJ95584.1};
GN   Name=gcvT_10 {ECO:0000313|EMBL:CUJ95584.1};
GN   ORFNames=PH7735_01888 {ECO:0000313|EMBL:CUJ95584.1};
OS   Shimia thalassica.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae.
OX   NCBI_TaxID=1715693 {ECO:0000313|EMBL:CUJ95584.1, ECO:0000313|Proteomes:UP000051870};
RN   [1] {ECO:0000313|Proteomes:UP000051870}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 7735 {ECO:0000313|Proteomes:UP000051870};
RA   Rodrigo-Torres Lidia, Arahal R.David.;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CYTW01000001; CUJ95584.1; -; Genomic_DNA.
DR   RefSeq; WP_058310966.1; NZ_CYTW01000001.1.
DR   AlphaFoldDB; A0A0P1IQT3; -.
DR   STRING; 1715693.PH7735_01888; -.
DR   GeneID; 83880926; -.
DR   Proteomes; UP000051870; Unassembled WGS sequence.
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000313|EMBL:CUJ95584.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000051870};
KW   Transferase {ECO:0000313|EMBL:CUJ95584.1}.
FT   DOMAIN          6..367
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          370..423
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          427..692
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          718..797
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   805 AA;  88593 MW;  D42337F6985A0E3C CRC64;
     MKTTTRVVVI GGGVVGCSVL YHLTKLGWSD VMLLERSELT SGSTWHAAGG FHTLNGDTNM
     AALQGYTIKL YKELEEITGM SCGLHHVGGV TLADNQERFD MLVAERAKHR FMGLDTEIVT
     PEEIKKIAPV TNTDGIIGGL YDPLDGHLDP SGTTHAYAKA ARMGGATIET HCMVKETNQR
     PDGTWDVVTD KGTIHAEHIV NAGGLWAREV GAMAGVYMPL HPMEHIYLVT DEVPMIAEII
     DGGGEHPHVM DPAGESYLRQ EGRGLCIGFY EQPCKPWAVE GTSWDFGHEL LPDNFDKIED
     SIDFAYKRFP ALEAAGIKSS IHGPFTFAPD GNPLVGPVPG MRNYWSACGV MAGFSQGGGV
     GLMLAQWMVE GECERDTMAM DIARFGDWIT PGYTLPKVIE NYQKRFSVSY PNEELPAARP
     FRTTPMYDIF DNMGAVWGAQ YGLEVANYFA EGDEPRFETP SFRRSNAFEA TAREVKAVRE
     AVGINETHNF GKYLVSGAGA RAWLDRIMAG RVPKPGRLSL TPMLSPKGRL IGDFTISCLS
     ETEFQLTASY GSQSYHMRWF QQNLDDGVAL QNISDTRNGF QIAGPMARDV LQACTRQDIS
     DMKFMDVRRM TVGMADCIVQ RVSYTGDLGY EIYCDLPSQR ALWDVLWTAG QPHGMKPFGM
     RAMMSLRLDK FFGSWLSEFS PDYTAAETGL DRFISFKKNT SFIGRAAAEA ERDAGATRKL
     CAFEVDAVDA DVNAYEPIWL DGAVVGFCTS GGYSHHAQKS IAQGFVPTDR AVEGLEVEIE
     ILGSMCKARL ITTPLFDEDG SRMRG
//