ID A0A0P4R1C6_9ACTN Unreviewed; 382 AA.
AC A0A0P4R1C6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Putative peptidase C40 family protein {ECO:0000313|EMBL:GAO05858.1};
GN ORFNames=TPA0598_01_02270 {ECO:0000313|EMBL:GAO05858.1};
OS Streptomyces lydicamycinicus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1546107 {ECO:0000313|EMBL:GAO05858.1, ECO:0000313|Proteomes:UP000048965};
RN [1] {ECO:0000313|Proteomes:UP000048965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110027 {ECO:0000313|Proteomes:UP000048965};
RA Komaki H., Ichikawa N., Katano-Makiyama Y., Hosoyama A., Hashimoto M.,
RA Uohara A., Kitahashi Y., Ohji S., Kimura A., Yamazoe A., Igarashi Y.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Streptomyces sp. NBRC 110027.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAO05858.1, ECO:0000313|Proteomes:UP000048965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110027 {ECO:0000313|EMBL:GAO05858.1,
RC ECO:0000313|Proteomes:UP000048965};
RX PubMed=26380643; DOI=10.1186/s40793-015-0046-5;
RA Komaki H., Ichikawa N., Hosoyama A., Fujita N., Igarashi Y.;
RT "Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a
RT producer of anti-MRSA antibiotic lydicamycins.";
RL Stand. Genomic Sci. 10:58-58(2015).
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO05858.1}.
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DR EMBL; BBNO01000001; GAO05858.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P4R1C6; -.
DR Proteomes; UP000048965; Unassembled WGS sequence.
DR Gene3D; 6.10.250.3150; -; 1.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR47359:SF3; NLPC_P60 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47359; PEPTIDOGLYCAN DL-ENDOPEPTIDASE CWLO; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000048965};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..41
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 42..382
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006068297"
FT DOMAIN 267..382
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
FT REGION 216..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 50..91
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 216..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 41542 MW; 33B23CEB2CB32EB4 CRC64;
MASHRKPRTS VLASPTGRRT AAGLTTAALA SVTLLSQSAD AAPRAPKPTV EEVKQKVDDL
YHQAEVATQK YNAAKERAET QRDTVDDLLD ASAKRAEKMN ESRRLLGTFA SAQYRTGGMN
PTAQLMLAKD PQQFVDRNHL MERLTGRQKQ AVTDYQEQQA AAAKQRAQAT RSLERLQASQ
ASLKESKRSV QDKLAEARQL LSRLTAQEKA RLAELERQKE AAAKRRAAEE ARKQQERERQ
RQQDGDGSTG GSTGGSTGGG STDDSASSKG AKALAFARAQ IGKPYVWGAT GPTSYDCSGL
TQAAWKAAGV DLPRTTWDQV KVGQRVATKD LQPGDLVFFY DDISHVGMYM GDGKMVHAPK
PGASVREESI YYMPIYGSVR PG
//
