ID A0A0P4RB85_9ACTN Unreviewed; 250 AA.
AC A0A0P4RB85;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Regulator of SigK {ECO:0000256|ARBA:ARBA00030803};
DE AltName: Full=Sigma-K anti-sigma factor RskA {ECO:0000256|ARBA:ARBA00029829};
GN ORFNames=TPA0598_07_05370 {ECO:0000313|EMBL:GAO10813.1};
OS Streptomyces lydicamycinicus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1546107 {ECO:0000313|EMBL:GAO10813.1, ECO:0000313|Proteomes:UP000048965};
RN [1] {ECO:0000313|Proteomes:UP000048965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110027 {ECO:0000313|Proteomes:UP000048965};
RA Komaki H., Ichikawa N., Katano-Makiyama Y., Hosoyama A., Hashimoto M.,
RA Uohara A., Kitahashi Y., Ohji S., Kimura A., Yamazoe A., Igarashi Y.,
RA Fujita N.;
RT "Whole genome shotgun sequence of Streptomyces sp. NBRC 110027.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:GAO10813.1, ECO:0000313|Proteomes:UP000048965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110027 {ECO:0000313|EMBL:GAO10813.1,
RC ECO:0000313|Proteomes:UP000048965};
RX PubMed=26380643; DOI=10.1186/s40793-015-0046-5;
RA Komaki H., Ichikawa N., Hosoyama A., Fujita N., Igarashi Y.;
RT "Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a
RT producer of anti-MRSA antibiotic lydicamycins.";
RL Stand. Genomic Sci. 10:58-58(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAO10813.1}.
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DR EMBL; BBNO01000007; GAO10813.1; -; Genomic_DNA.
DR RefSeq; WP_042158457.1; NZ_BBNO01000007.1.
DR AlphaFoldDB; A0A0P4RB85; -.
DR OrthoDB; 153510at2; -.
DR Proteomes; UP000048965; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.10.1320; Anti-sigma factor, zinc-finger domain; 1.
DR InterPro; IPR018764; Anti-sigma_K_RskA.
DR InterPro; IPR041916; Anti_sigma_zinc_sf.
DR InterPro; IPR027383; Znf_put.
DR PANTHER; PTHR37461; ANTI-SIGMA-K FACTOR RSKA; 1.
DR PANTHER; PTHR37461:SF1; ANTI-SIGMA-K FACTOR RSKA; 1.
DR Pfam; PF10099; RskA; 1.
DR Pfam; PF13490; zf-HC2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000048965};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 11..36
FT /note="Putative zinc-finger"
FT /evidence="ECO:0000259|Pfam:PF13490"
SQ SEQUENCE 250 AA; 26036 MW; C2DE8CE8250F3E61 CRC64;
MSTVDLHTLT GAYALGALSE QESAEFTRHL AQCPACTQEV RELQETAARL ALAVAEVPPA
GLRTRVMAAL PEVRQLPPRG RHATATVVPL RRGIRFRLPY LAAAACLVVA ALAGGLAVHA
RNEADQQRDR TVRAEQQAAA VSALMTAPDA TFHTTALKGG GSGTVVASKR RGQTAFLYHG
LPALSGQRVY ELWYSRNGAM EPAGLVRTGS SSGAMLLTGG PQGADGVGVT AEPPGGSSRP
TTTPLAVLRL
//
