ID   A0A0P6AC75_9CRUS        Unreviewed;       558 AA.
AC   A0A0P6AC75;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Vacuolar fusion protein MON1 homolog {ECO:0000256|RuleBase:RU367048};
GN   ORFNames=APZ42_025206 {ECO:0000313|EMBL:KZS10350.1};
OS   Daphnia magna.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC   Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX   NCBI_TaxID=35525 {ECO:0000313|EMBL:JAM59117.1};
RN   [1] {ECO:0000313|EMBL:JAM59117.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Gilbert D., Podicheti R., Orsini L., Colbourne J., Pfrender M.;
RT   "Daphnia magna gene sets from two clonal populations assembled and
RT   annotated with EvidentialGene.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:JAM59117.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Gilbert D.G.;
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:KZS10350.1, ECO:0000313|Proteomes:UP000076858}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Xinb3 {ECO:0000313|EMBL:KZS10350.1,
RC   ECO:0000313|Proteomes:UP000076858};
RC   TISSUE=Complete organism {ECO:0000313|EMBL:KZS10350.1};
RA   Gilbert D.G., Choi J.-H., Mockaitis K., Colbourne J., Pfrender M.;
RT   "EvidentialGene: Evidence-directed Construction of Genes on Genomes.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in membrane trafficking through the
CC       secretory apparatus. {ECO:0000256|RuleBase:RU367048}.
CC   -!- SIMILARITY: Belongs to the MON1/SAND family.
CC       {ECO:0000256|ARBA:ARBA00008968, ECO:0000256|RuleBase:RU367048}.
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DR   EMBL; GDIP01044598; JAM59117.1; -; Transcribed_RNA.
DR   EMBL; LRGB01001834; KZS10350.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0P6AC75; -.
DR   STRING; 35525.A0A0P6AC75; -.
DR   EnsemblMetazoa; XM_032927468.2; XP_032783359.1; LOC116921211.
DR   OrthoDB; 73361at2759; -.
DR   Proteomes; UP000076858; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR043972; FUZ/MON1/HPS1_longin_1.
DR   InterPro; IPR043971; FUZ/MON1/HPS1_longin_2.
DR   InterPro; IPR043970; FUZ/MON1/HPS1_longin_3.
DR   InterPro; IPR004353; Mon1.
DR   PANTHER; PTHR13027; SAND PROTEIN-RELATED; 1.
DR   PANTHER; PTHR13027:SF7; VACUOLAR FUSION PROTEIN MON1 HOMOLOG; 1.
DR   Pfam; PF19036; Fuz_longin_1; 1.
DR   Pfam; PF19037; Fuz_longin_2; 1.
DR   Pfam; PF19038; Fuz_longin_3; 1.
DR   PRINTS; PR01546; YEAST73DUF.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000076858}.
FT   DOMAIN          155..277
FT                   /note="FUZ/MON1/HPS1 first Longin"
FT                   /evidence="ECO:0000259|Pfam:PF19036"
FT   DOMAIN          317..416
FT                   /note="FUZ/MON1/HPS1 second Longin"
FT                   /evidence="ECO:0000259|Pfam:PF19037"
FT   DOMAIN          447..547
FT                   /note="FUZ/MON1/HPS1 third Longin"
FT                   /evidence="ECO:0000259|Pfam:PF19038"
FT   REGION          112..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..142
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   558 AA;  63177 MW;  81819049B7DAA99F CRC64;
     MASEVVDCEV VFPLNTVDIL GTATDSSHAI LDSSDPYENL NNLTGARTNC DSNDVSLNIQ
     PHGCTDGFRN GDVGLLEIAV EAQPDLVFES DLVSINQDQQ FIRPRVYLER ESFSNQNEDS
     MSRTTNASSI LDDNSTPAGD EESGSDSLLW KNQRKHFFVL SEAGKPIYTR HGNEEQLVTL
     FGVMQALVSF VEDGEDSMDM ILAGDTKFVF LHKTPLILVA VSKMRDSVLQ LLLQLEYIFN
     QISSVITRTH LEKIFEQRRN YDLRRLLAGS ERLMDNLVNY MDNDFSVLLG AVKCLPMPAS
     DRDAVTQTIH QQCNKIKNLV FTVLIGNNQL ISLVRVNKKH LLHPSDVHLI INLVNSSETF
     KTAEGWTPIC LPHFDPRSFL YVHASYLSED CQACMLFFTT DRDSFFSLSD AKKNIVDRLR
     RHNNILESIT LALNSTYPII SQLGCANVRH FVYKSRLSAQ YTNANNGPPY QHEQGQLYLM
     DLYRHMHGRM HSASRPLKTM CHTTEKEILF GLVTPSYELY MILEPMTTKP AIMNAANAVL
     KWTKREEESH FITTSGSW
//