ID A0A0P6S7L3_9STRE Unreviewed; 340 AA.
AC A0A0P6S7L3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Probable heme-iron transport system permease protein IsdF {ECO:0000256|ARBA:ARBA00018524};
DE AltName: Full=Iron-regulated surface determinant protein F {ECO:0000256|ARBA:ARBA00031465};
DE AltName: Full=Staphylococcal iron-regulated protein G {ECO:0000256|ARBA:ARBA00031149};
GN ORFNames=AKK44_05375 {ECO:0000313|EMBL:KPJ22308.1};
OS Streptococcus phocae.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=119224 {ECO:0000313|EMBL:KPJ22308.1, ECO:0000313|Proteomes:UP000049578};
RN [1] {ECO:0000313|EMBL:KPJ22308.1, ECO:0000313|Proteomes:UP000049578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51973 {ECO:0000313|EMBL:KPJ22308.1,
RC ECO:0000313|Proteomes:UP000049578};
RA Avendano-Herrera R.;
RT "Genome sequence of Streptococcus phocae subsp. phocae ATCC 51973T isolated
RT from liver specimen obtained from seal.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC heme-iron. Responsible for the translocation of the substrate across
CC the membrane. {ECO:0000256|ARBA:ARBA00025320}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. FecCD subfamily. {ECO:0000256|ARBA:ARBA00007935}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPJ22308.1}.
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DR EMBL; LHQM01000020; KPJ22308.1; -; Genomic_DNA.
DR RefSeq; WP_054278846.1; NZ_LHQM01000020.1.
DR AlphaFoldDB; A0A0P6S7L3; -.
DR STRING; 119224.AKK44_05375; -.
DR PATRIC; fig|119224.3.peg.616; -.
DR Proteomes; UP000049578; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06550; TM_ABC_iron-siderophores_like; 1.
DR Gene3D; 1.10.3470.10; ABC transporter involved in vitamin B12 uptake, BtuC; 1.
DR InterPro; IPR037294; ABC_BtuC-like.
DR InterPro; IPR000522; ABC_transptr_permease_BtuC.
DR PANTHER; PTHR30472; FERRIC ENTEROBACTIN TRANSPORT SYSTEM PERMEASE PROTEIN; 1.
DR PANTHER; PTHR30472:SF21; HEME-IRON TRANSPORT SYSTEM PERMEASE PROTEIN ISDF-RELATED; 1.
DR Pfam; PF01032; FecCD; 1.
DR SUPFAM; SSF81345; ABC transporter involved in vitamin B12 uptake, BtuC; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 340 AA; 36391 MW; A0DA844951BC6AD1 CRC64;
MSEMSNKNDQ TIMLKKRRLK LIYFILLGVC LLLLGLHAIS VGGLSVSYRT IFEGLFVSYN
PEVALIYDLR FPRVVIALLA GGAIAVSGVL FQSVLKNPIA DPAIIGVCSG ASFMVLLSSV
FLPHLLLYGP LLSFVGGGLS FALIYTLSWR KGLQPIRIIL TGIAINALFM GLSNALVGFS
ASSSPVVNAL ISGNISQKTW GDVGILLPYT CVGLVLAVLV SKQCDLLLLD DKVIRNLGID
SNYLRLGISL LAILLASVAT SVVGLVSFLG LIVPHIGRLL VGNKHIFLIP FSALMGAFVF
LLADTLGRSL AYPLEISPAI VMSVIGGPYF IYLLRRSDLI
//
