ID A0A0P6WRY6_9CHLR Unreviewed; 325 AA.
AC A0A0P6WRY6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=HTH merR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ADM99_07415 {ECO:0000313|EMBL:KPL72868.1};
OS Leptolinea tardivitalis.
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Leptolinea.
OX NCBI_TaxID=229920 {ECO:0000313|EMBL:KPL72868.1, ECO:0000313|Proteomes:UP000050430};
RN [1] {ECO:0000313|EMBL:KPL72868.1, ECO:0000313|Proteomes:UP000050430}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YMTK-2 {ECO:0000313|EMBL:KPL72868.1,
RC ECO:0000313|Proteomes:UP000050430};
RA Hemp J., Ward L.M., Pace L.A., Fischer W.W.;
RT "Genome sequence of Leptolinea tardivitalis DSM 16556.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPL72868.1}.
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DR EMBL; LGCK01000007; KPL72868.1; -; Genomic_DNA.
DR RefSeq; WP_062421009.1; NZ_LGCK01000007.1.
DR AlphaFoldDB; A0A0P6WRY6; -.
DR STRING; 229920.ADM99_07415; -.
DR OrthoDB; 9800334at2; -.
DR Proteomes; UP000050430; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd02065; B12-binding_like; 1.
DR CDD; cd01104; HTH_MlrA-CarA; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036594; Meth_synthase_dom.
DR PANTHER; PTHR30204:SF67; HTH-TYPE TRANSCRIPTIONAL REGULATOR MLRA-RELATED; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000050430}.
FT DOMAIN 14..83
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT DOMAIN 196..325
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 325 AA; 36219 MW; 7B80DA014B46D885 CRC64;
MTLSSIDTIS DDPKYTIKAV CEQTGVLPVT LRAWERRHEV LNPQRGDNRY RLYSDRDIAT
LRWIKNRLDS GISISSAVSE LRQMQQNGGQ LETVPTIPFS TPKPVTPAVP PEQIAHELYL
ALIKHDEDRA SELLHQAYSM YDLYTYILKT QIPCLVEIGE AWANGIIPVA TEHFASAYLR
GNLLTIFQAY PARNSAPFIL VGCAPTELHE IGSLMLAVML RSEGYRVEYL GPDLPLDDLV
DYARYEHPAM VVMAATSLES AELIDHLNEK LSKLKPAPVL GFGGSAFNQQ PDLIEKISGK
FLGLSLDSAV ESVKQMLPVT RKSPR
//
