ID   A0A0P6X1W0_9CHLR        Unreviewed;      1038 AA.
AC   A0A0P6X1W0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Membrane protein {ECO:0000313|EMBL:KPL73278.1};
GN   ORFNames=ADM99_03385 {ECO:0000313|EMBL:KPL73278.1};
OS   Leptolinea tardivitalis.
OC   Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC   Leptolinea.
OX   NCBI_TaxID=229920 {ECO:0000313|EMBL:KPL73278.1, ECO:0000313|Proteomes:UP000050430};
RN   [1] {ECO:0000313|EMBL:KPL73278.1, ECO:0000313|Proteomes:UP000050430}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YMTK-2 {ECO:0000313|EMBL:KPL73278.1,
RC   ECO:0000313|Proteomes:UP000050430};
RA   Hemp J., Ward L.M., Pace L.A., Fischer W.W.;
RT   "Genome sequence of Leptolinea tardivitalis DSM 16556.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPL73278.1}.
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DR   EMBL; LGCK01000006; KPL73278.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0P6X1W0; -.
DR   STRING; 229920.ADM99_03385; -.
DR   Proteomes; UP000050430; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 2.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR023908; xxxLxxG_rpt.
DR   NCBIfam; TIGR03057; xxxLxxG_by_4; 1.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050430};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        282..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        311..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        874..892
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        898..919
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        931..950
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        970..991
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1003..1023
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          72..369
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
FT   DOMAIN          711..1029
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
SQ   SEQUENCE   1038 AA;  113138 MW;  8FD1DA6D9EF1037B CRC64;
     MDLNRLLKHG WIPVVIWVLI FTAVILTMPD MGLLVREKGQ VVVGSTYPSS IGDDILKKIN
     NPGSKNAKEI SVALIYYNPN KLNDKDRLQI KVRMDLLEQM KEKYHIVSMD NLFTNEDLAD
     SLTSKDGTTI LVPLTIDKAN RSVSNIRDEI TNVSKVDGVQ LYTTSADLVT EDFILTTEKG
     VEQTEIITIV FIILVLLIIF RSPITPFVTI ISVGLSFFTA LNVVLQLVKF GNFPISSFTK
     VFLILVLFGI GTDYTMLLLM RYKEELYKGI EKKEAVLTAY KTAGKTVFLS SLTILIGFTC
     LYFAQFCTYR SAAAVAIGVA ILLVVLFTFV PGMMILLGKN LFWSPFHTEG HSDSKAWQWV
     SAFSVKYPGI TLLFTVLICG LIFFYNDNLS YNNMKEVGKQ YSSITGNNIV TAHFSKGQVM
     PVTIAIDSKS GLDNQIDLSS LDSLTEAVKR VDGVEKVYSV TQPKGDRLKE LYLNDQADTL
     DNGLNDAKDG LTQIQNGLQD AIKQMNASTD SMDSIQQLQD GANDLIYGLD KLTEAGIEFR
     DKLKDGSGSA EELSNGIQKV DKSIGSVENG LTQLYNGYTQ ISNGLGTIDT NLQGIMTGLS
     GIKTGLEGIV TMQGQLAANP AYAGTLMVDP VFQTMVGTTN ALNNQFGTLQ AGVSQLEAGV
     AHAKSSLDTA NAGLAQAQAG LSQIKSGTSQ LAEGGLEMND SISGAAQAQS QIVDGMATLD
     SGAKKLREGQ NQLIDGLSKL SSQVKELKNG LNDAKNGVTT INDGLGSAND YLTKLSTSKV
     STGTFYIPAD KIHESDFTRS MNTYMSKDRK TTKILITLNV DPYTRDGMKV VDNISKVVSA
     FVPNSTLKDS SWGITGITQT NNDLKAMSSS DFTFARVIML IGIFIVLIFI TRDIWMPIFV
     MISLLASYFL AISLSSLFFQ HVARIGDLSW NVPFCSFIMI VTLGVDYSIF LIMRHKENEN
     MKETDSITQA AFKVGSVIIS AGLILSGTFA SMYPSGVDTL MEIAVTVIVG IAMLCLVFLP
     VFIPTMVSLK TKLIGIKD
//