ID A0A0P7APZ0_9HYPO Unreviewed; 807 AA.
AC A0A0P7APZ0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 08-NOV-2023, entry version 22.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=AK830_g10473 {ECO:0000313|EMBL:KPM36110.1};
OS Neonectria ditissima.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM36110.1, ECO:0000313|Proteomes:UP000050424};
RN [1] {ECO:0000313|EMBL:KPM36110.1, ECO:0000313|Proteomes:UP000050424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R09/05 {ECO:0000313|EMBL:KPM36110.1,
RC ECO:0000313|Proteomes:UP000050424};
RA Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT ditissima.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM36110.1}.
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DR EMBL; LKCW01000218; KPM36110.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7APZ0; -.
DR STRING; 78410.A0A0P7APZ0; -.
DR OrthoDB; 1369806at2759; -.
DR Proteomes; UP000050424; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF41; MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000050424}.
FT DOMAIN 218..360
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 363..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..535
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 807 AA; 86758 MW; 98E8B63C0853C9B2 CRC64;
MAISALPLST TRLLGSTVVI TNPVSLVKEL IDNGVDAGAT SIDVSISPNT VDKIQVRDNG
RGIQVDDFDL LGRRAHTSKL RKFEELETKA GQSLGFRGEA LASANSLAIV KVTTKTARDP
VASLLLLKFS DGGVKKKNPV AAPVGTTVQA LQLFENVPVR KHMALKESRK TLLSIKRLLE
TYAIALPRIR LSLKVSGDHQ KSWSYSPSSS SANAREAATQ IFGHSLVSQC VEVTASLSTG
GTGTSLGTTW GTLSALLPRN DGQLREITGK RQFISVDSRP ILSSRGTGKK IVTMFKKELA
LALDSGELLT SLSNPFMQLS IDCNPGSYDP NVSPLKDEVM FKDEQGLLDS FQALCARVYK
PGGSSVSTKQ SQSGSKPHDG ISGTDKQFAG SQLGMLDVNS QLGLGSKATP VDVNTFEDID
DFPIDLELLE SFDDELEGII GTSGNTSQGA VEFKIQPAPS CPQANAKVSS VTDSLQTISA
MMRTRTTVNL ARKQSDNSDE GSTLGLVPVQ VVPRRESPTA PNETRSRPDD NDVAPLHRLE
DIGLYFQPKK DQPIEIASDE TATLGNAHGE EPNIPDPTKP RELGRRPLME LTDSMLNTLR
NEDEEEEEPI QPGTTNFSSP EPDLLLPHNA IRGLVVPLTR RGPGVAGGEL GLTSDERHWT
GLLSSRTPPG SAVRTQRRAH AAFDTSPARD EFAALQTPPS SDTLPPARVS RPSTLIHRGA
SHTGIQRMSR GVGGLPENVF GDDELTQAVT SFGNGSSGES DERFMNEQPN RNLIFGKGSS
TVSRLDELDL HLKSTAKRHE GLEHKRG
//
