ID A0A0P7ATX0_9HYPO Unreviewed; 425 AA.
AC A0A0P7ATX0;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Transcription factor IWS1 {ECO:0000313|EMBL:KPM36687.1};
GN ORFNames=AK830_g9876 {ECO:0000313|EMBL:KPM36687.1};
OS Neonectria ditissima.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM36687.1, ECO:0000313|Proteomes:UP000050424};
RN [1] {ECO:0000313|EMBL:KPM36687.1, ECO:0000313|Proteomes:UP000050424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R09/05 {ECO:0000313|EMBL:KPM36687.1,
RC ECO:0000313|Proteomes:UP000050424};
RA Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT ditissima.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPM36687.1}.
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DR EMBL; LKCW01000194; KPM36687.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7ATX0; -.
DR STRING; 78410.A0A0P7ATX0; -.
DR OrthoDB; 12240at2759; -.
DR Proteomes; UP000050424; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000050424}.
FT DOMAIN 241..318
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..50
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 48339 MW; 104FF24E4E228DC2 CRC64;
MSDNESPVGS PANEPIDNGR ERDHAAADDS DKESDLLSEV DEDQFEDYDP ETANIEDRPV
DIDEDIARTL KATKRKRADG EVAKKPREGR REKKRRDRDD DVAMDDGADE GGKQMRRSRR
QGEGERRPRA KAATPEPENE DHLSPEEKRK RAIDRALDAA IKKPSGPKRR KKDEIDLEDE
IDEQLADLKV QMERACQADN QAREAGQPAL HKLKLLPDVT AILNRNNVQH AVLDPDTNFL
QHVKFFLEPL NDGSLPAYNI QRDIFMALTK LNVEKETLLS SGIGKVVFFY TRSKKPEASI
KRMAQRLLGE WSRPILKRTD DYKKRHIETR EFDYQAAKMA QRQKTNSQFS LTQRPAVSAR
DAERERFLAP ARTNNQARMA NLPSSYTIAP KSTFDGPSGG MEHRPLGAGG MEAFRKMTQK
SKRKN
//
