ID   A0A0P7BJE3_9HYPO        Unreviewed;       554 AA.
AC   A0A0P7BJE3;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Uracil permease {ECO:0000313|EMBL:KPM45309.1};
GN   ORFNames=AK830_g1141 {ECO:0000313|EMBL:KPM45309.1};
OS   Neonectria ditissima.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Neonectria.
OX   NCBI_TaxID=78410 {ECO:0000313|EMBL:KPM45309.1, ECO:0000313|Proteomes:UP000050424};
RN   [1] {ECO:0000313|EMBL:KPM45309.1, ECO:0000313|Proteomes:UP000050424}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R09/05 {ECO:0000313|EMBL:KPM45309.1,
RC   ECO:0000313|Proteomes:UP000050424};
RA   Gomez-Cortecero A., Harrison R.J., Armitage A.D.;
RT   "Draft genome of a European isolate of the apple canker pathogen Neonectria
RT   ditissima.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC       {ECO:0000256|ARBA:ARBA00008974}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPM45309.1}.
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DR   EMBL; LKCW01000008; KPM45309.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0P7BJE3; -.
DR   OrthoDB; 1218881at2759; -.
DR   Proteomes; UP000050424; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR   Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR   InterPro; IPR012681; NCS1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR   NCBIfam; TIGR00800; ncs1; 1.
DR   PANTHER; PTHR30618:SF2; ALLANTOIN PERMEASE-RELATED; 1.
DR   PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050424};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        49..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        77..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..352
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        373..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        403..422
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        452..474
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        480..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          531..554
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   554 AA;  61686 MW;  88826053FB2B7B0B CRC64;
     MTSGPRLRTW ANKLAVESEP GLTKAQLMLT NHDLKPVEKE RRQWGPWNFV GFWIADSFNI
     NTWMISSSMI VGGLSWWQAW ICVWVGYTFT GVFVAMNARF GAMYHIGFPV ANRSSFGIWG
     SLWPVFNRAA MACVWYGVQS YIGGHCVYIM IRSIWKSWDR ETIPNTFSEN SGTTTADFAS
     FFLFWFLSLP AIWFPVHKIR HLFTVKAYIV PCAGLAYLGW AVSRAGGIGP IIKQKNSVHG
     SELGWQIVKG IMSSIANFAT LIVNGSDFSR FARKPTDALW SQMITIPIGF AFTSFIGIIV
     SSSSTVIYNE TIWDPLALLE RFIDDGGSAQ RFGVFVIAFA FALAQLGTNI AANSVSAGTD
     MTALFPRYIN IRRGGYICAA IGLAMCPYNL LTDSNKFTTY LSAYSVFLSS IAGVMVSDYY
     LVRKGYLEIK ELYDGRKSGP YFYTYGFHWR GYVAYIAGIL INVVGFVGAI GSKVPVGATY
     IYNLNYFFGF GVALGTYWLL CKISPVPATS DRWMEVGDEI DDVRVGYSAD SPTYDEEHVT
     GSDSKGVDGY TKQF
//