ID   A0A0P7GYS0_9EURY        Unreviewed;       304 AA.
AC   A0A0P7GYS0;
DT   20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT   20-JAN-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=cysteine--tRNA ligase {ECO:0000256|ARBA:ARBA00012832};
DE            EC=6.1.1.16 {ECO:0000256|ARBA:ARBA00012832};
DE   AltName: Full=Cysteinyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031499};
GN   ORFNames=SY89_01389 {ECO:0000313|EMBL:KPN30653.1};
OS   Halolamina pelagica.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Halorubraceae.
OX   NCBI_TaxID=699431 {ECO:0000313|EMBL:KPN30653.1, ECO:0000313|Proteomes:UP000050535};
RN   [1] {ECO:0000313|Proteomes:UP000050535}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDK2 {ECO:0000313|Proteomes:UP000050535};
RA   Hoang H.T., Killian M.L., Madson D.M., Arruda P.H.E., Sun D.,
RA   Schwartz K.J., Yoon K.;
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KPN30653.1}.
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DR   EMBL; LGUC01000001; KPN30653.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0P7GYS0; -.
DR   STRING; 699431.SY89_01389; -.
DR   PATRIC; fig|699431.3.peg.1421; -.
DR   Proteomes; UP000050535; Unassembled WGS sequence.
DR   GO; GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR024909; Cys-tRNA/MSH_ligase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR032678; tRNA-synt_1_cat_dom.
DR   PANTHER; PTHR10890:SF3; CYSTEINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR   PANTHER; PTHR10890; CYSTEINYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF01406; tRNA-synt_1e; 1.
DR   PRINTS; PR00983; TRNASYNTHCYS.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE   4: Predicted;
KW   Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:KPN30653.1};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050535}.
FT   DOMAIN          20..253
FT                   /note="tRNA synthetases class I catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01406"
FT   REGION          196..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   304 AA;  33886 MW;  AB5B73ED952A4F1B CRC64;
     MTLSLTDTLS GEREPFEASG ESVRLYVCGL TVSDDPHLGH ARLWAQADIL HRWLAHEGYD
     VRHVENVTDV NEKITARVGE REAWETEADV ARHYTNEVLQ RMRDLNLLRA EVYPRVSEHV
     PEIVELVETL IEQGYAYESN GSVYFDVTAF TEYGKLSNQE IDAVEEQGDP DERGEKRNPA
     DFALWKAGGV DADAVEEHRK HEHDGPLPEG QTWASPWGEG RPGWHIECSA MSMTHLGETL
     DIHMGGQDLV FPTTRTRSPR ARPRRASDSR TTGSTSASCR PAARRCPPRS ATTSLSPTPS
     VSSA
//