ID A0A0P7KKD6_9RHOB Unreviewed; 902 AA.
AC A0A0P7KKD6;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=AKJ29_08980 {ECO:0000313|EMBL:KPN62362.1};
OS Aliiroseovarius crassostreae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Aliiroseovarius.
OX NCBI_TaxID=154981 {ECO:0000313|EMBL:KPN62362.1, ECO:0000313|Proteomes:UP000050471};
RN [1] {ECO:0000313|EMBL:KPN62362.1, ECO:0000313|Proteomes:UP000050471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CV919-312 {ECO:0000313|EMBL:KPN62362.1,
RC ECO:0000313|Proteomes:UP000050471};
RA Kessner L., Spinard E., Nelson D.;
RT "Draft genome sequence of Aliiroseovarius crassostreae CV919-312TSm, the
RT causative agent of Roseovarius Oyster Disease (formerly Juvenile Oyster
RT Disease).";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPN62362.1}.
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DR EMBL; LKBA01000019; KPN62362.1; -; Genomic_DNA.
DR RefSeq; WP_055191988.1; NZ_LKBA01000019.1.
DR AlphaFoldDB; A0A0P7KKD6; -.
DR STRING; 154981.AKJ29_08980; -.
DR REBASE; 146734; Acr312ORF8980P.
DR OrthoDB; 9806213at2; -.
DR Proteomes; UP000050471; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR046818; MmeI_C.
DR InterPro; IPR046819; MmeI_hel.
DR InterPro; IPR046816; MmeI_Mtase.
DR InterPro; IPR046817; MmeI_N.
DR InterPro; IPR046820; MmeI_TRD.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841:SF6; DNA METHYLTRANSFERASE A; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF20467; MmeI_C; 1.
DR Pfam; PF20465; MmeI_hel; 1.
DR Pfam; PF20473; MmeI_Mtase; 1.
DR Pfam; PF20464; MmeI_N; 1.
DR Pfam; PF20466; MmeI_TRD; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000050471};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..159
FT /note="MmeI-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF20464"
FT DOMAIN 171..248
FT /note="MmeI-like helicase spacer"
FT /evidence="ECO:0000259|Pfam:PF20465"
FT DOMAIN 324..586
FT /note="MmeI-like DNA-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF20473"
FT DOMAIN 603..806
FT /note="MmeI-like target recognition"
FT /evidence="ECO:0000259|Pfam:PF20466"
FT DOMAIN 808..883
FT /note="MmeI-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20467"
SQ SEQUENCE 902 AA; 101582 MW; 821FC90D713A9830 CRC64;
MNPTEIFEAL EQISDKPFNA EEFPFEFAQA TDVAQAAIAK LRNGTTNKSD QPGGVLVNKK
FHFAPAMTGM ADVTLEALRN SKKTATAKPA ILIATDGEMV AAQQRVSGET LHCRFDEIGD
KFGFFLPAAG KERYEAAEEN PIDVKVTAKL AKLYDALVKK NPDWASDERR HEMNQLMMRL
IFCMFAEDVG IFPDNQFSQI LFNHAGNKGE EAREVIIAAF SAMNLPKDKR DDLPAWTGEL
DYVNGGLFAG SIDAPVFDVT AYRYLRDACG EDWREINPDI FGSMIQSVAD PKQRSELGMH
YTSVPNIMKV IGPLFLDDLD GEINKAWEKP TALVRVLDRL EGIRVFDPAC GSGNFLVVSY
RQLREREMRV LERLEALKHN KQNVMFSRVR IENFHGIEIT DFAAETAKLA LFIAEYQANA
VFKEVFGQGP ASLPLRESAH IVCDNALRVD WEEVCPPPAE GEEVFIAGNP PFVGTTYRTK
EQRADFNDVF AGNIRNAGRL DFSTAWMFLA SNYVRNFRAK SSLITTSSTV QGAAVEPLWS
NILNDGVKIF FAHRPFKWRN NAAKNAAVEC VIVGLSAQPH RSLVLFEGDL KKECNQINAY
LIDGDEVFVE ATRSGLFGLH SMGPGNFPYD FGHLILSPSE KEALIESAPA SEQFVYKFVG
SQEVIKGIER HCLWIDDDKV AEAQSIEEIR ERIEKVRHDR SQSTDAGTNR LAARPHQFRE
HNAPKSHMIL VPRTSSERRD YLPVDRAAGK IVSSDNNQVL YDAPEWCLAL VASRIHLVWI
AAVCGKLKSD FRYSNTLGWN TFPVPKFSDD QLEELNASAR KILKCRYSHY PATIAELYDP
DKMPDDLRAV HRENDELLET MYIGRPFRND SERLEHLFKL YAAKIKQIEK QAAKSKRGKR
SK
//
