ID A0A0P7TWW3_SCLFO Unreviewed; 343 AA.
AC A0A0P7TWW3;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Growth/differentiation factor 15-like {ECO:0000313|EMBL:KPP58378.1};
GN ORFNames=Z043_123802 {ECO:0000313|EMBL:KPP58378.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP58378.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP58378.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP58378.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP58378.1}.
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DR EMBL; JARO02014084; KPP58378.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7TWW3; -.
DR STRING; 113540.ENSSFOP00015032583; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19376; TGF_beta_GDF15; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF78; GROWTH_DIFFERENTIATION FACTOR 15; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 225..343
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 64..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 343 AA; 39574 MW; 7A6C4F07E0A71E49 CRC64;
MWCSCGPQRG RVDRELQLEA VKKGTLESLG FKGPPGRKEE AQEQEMRRRM QLFYEELLEL
HRNTSRADET EPALRRPPTV LSSAQEPLKV SQSCPYGDRF RAIFNKTHLI RKELTVAHAQ
MKISGEFHHQ SRSGNSQQLS QAVQIKIYRR DDEMKMHFEK KALVLTKVFY GKSLIVNTGV
PVEEWNLNSE EPLVLEVEFV MCGSWCLQET PRISLEMEIS TPEPKRRRQR RRASKDEDCE
EDECCCRKSL TVSFKDIGWS DWVVAPESYT MYFCAGSCPH NYKPASMHTQ IKSRVYHLTK
GATPRPSCVP AAYEPMLLMH YNSDGKLTYT LFNELVVSKC HCA
//
