ID A0A0P7U5S9_SCLFO Unreviewed; 397 AA.
AC A0A0P7U5S9;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Bone morphogenetic protein 2-B-like {ECO:0000313|EMBL:KPP69501.1};
GN ORFNames=Z043_111739 {ECO:0000313|EMBL:KPP69501.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP69501.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP69501.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP69501.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP69501.1}.
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DR EMBL; JARO02003925; KPP69501.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7U5S9; -.
DR STRING; 113540.ENSSFOP00015013388; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13765; TGF_beta_ADMP; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR PANTHER; PTHR11848:SF277; TGF_BETA_2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..397
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5006143177"
FT DOMAIN 279..397
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 397 AA; 45117 MW; DB1909F52FC69EC5 CRC64;
MLLPGRLWLC CALSLAPWAG SPLGVSTQVM RHTDADPVVT SQALRKLHEM LQIGEPEQNA
PPHRKPPQFM MDLYNAVADR NGVTKERKFL EGNVVRSFED RAAVRSPRNV HFFNLSSFGK
NEKMIKAEFR MFRSRHKFFL SRKSHRGHLY KISIYELLDN KVNPWRGSLV TSRFLSLYTQ
GWHVFDVTNT VSKWIQNSDE NKGFLVVITL PSENFLDYDT PAVDLKLEEK NSYLVIFSEE
GRRTSKTDQL PFHGQRRRSA AEAAGEVNSV VSRGRTKSRN TRAAPWYSRG RSVTCRQHPL
YVDFDKIGWS GWIISPRGYD AYYCSGTCPF PLGEGFGATN HATVQSIVNA LKLTTGVETP
CCVPDKLHSI SLLYFDDDEN VVLKQYENMV AVSCACH
//
