ID A0A0P7UX96_SCLFO Unreviewed; 1863 AA.
AC A0A0P7UX96;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Integrin beta {ECO:0000256|RuleBase:RU000633};
GN ORFNames=Z043_115169 {ECO:0000313|EMBL:KPP66336.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP66336.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP66336.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP66336.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251,
CC ECO:0000256|RuleBase:RU000633}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU000633}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the integrin beta chain family.
CC {ECO:0000256|ARBA:ARBA00007449, ECO:0000256|RuleBase:RU000633}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP66336.1}.
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DR EMBL; JARO02005705; KPP66336.1; -; Genomic_DNA.
DR STRING; 113540.ENSSFOP00015005777; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.2030; -; 2.
DR Gene3D; 4.10.1240.30; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR038081; CalX-like_sf.
DR InterPro; IPR003644; Calx_beta.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR040622; I-EGF_1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015812; Integrin_bsu.
DR InterPro; IPR012896; Integrin_bsu_tail.
DR InterPro; IPR036349; Integrin_bsu_tail_dom_sf.
DR InterPro; IPR002369; Integrin_bsu_VWA.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10082; INTEGRIN BETA SUBUNIT; 1.
DR PANTHER; PTHR10082:SF42; INTEGRIN BETA-4; 1.
DR Pfam; PF03160; Calx-beta; 2.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF18372; I-EGF_1; 1.
DR Pfam; PF07965; Integrin_B_tail; 1.
DR Pfam; PF00362; Integrin_beta; 1.
DR PRINTS; PR01186; INTEGRINB.
DR SMART; SM00237; Calx_beta; 2.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00187; INB; 1.
DR SMART; SM01242; Integrin_B_tail; 1.
DR SUPFAM; SSF141072; CalX-like; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF69687; Integrin beta tail domain; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS00243; INTEGRIN_BETA; 2.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|RuleBase:RU000633};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU000633};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000633}.
FT DOMAIN 1138..1227
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1568..1661
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 1681..1777
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1361..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1393..1431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1402..1431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1863 AA; 207028 MW; 6DCFD0D6E28E6E5A CRC64;
MTHLDFTFPR CDIQENLKSN GCKVKVTMSS KMTIEKSDTI STSLNVAQVY PKLMSMSLLP
GEEREVAMEI FEPEKGPLDL YILMDFSNSM EDDLDNLKRM GAELADLVGT LSNDYTIGFG
KFVDKVTEPQ TDMRPSKLKQ PWPNSDPPFS FQNTIPLTSN ISLFRVKLEK ERISGNLDAP
EGGFDAILQA AVCQRQIGWR KDATHLLVFS TESAFHYEAD GTNVLAGILP RNDEQCHLTE
DGSYTHDTLQ DYPSVPTLVR LLGKHNIIPI FAVTNHSYSY YEKLHSYFPI ADIGELQEDS
SNILSIMKSA FTNIRSKISM RAEDKPRAVE TMFLQSSGLL NKDGTFSNTP GQKGAFRMRV
KAHKKVGEQQ VCSLSEAERK GMMRVKPTTF SAYLGVETEV LCATCECEKN PEKNAKWCSN
NGDLICGMCK CYAGWLGPFC NCSAALSNSD YQGCKTPDSQ AVCSNHGDCL CGTCICHNPQ
QYEGPYCQYD KTQCARFSGF LCNDRGRCYM GSCACEAGWE GSACECPKSN QTCLDSKGGI
CNGRGTCQCG RCVCDNSNIA LSPTCEIGFQ AQLGMCEDRR TCVQCQAWKT GELKGEKCKD
CPFKITMVDE LKDSNRVIEK CSFRDEEDDC TYHYSVEYPS DPTDTTDEVQ VLKKKGRMVG
FKEDQYMLRH STLTSDYLDT PLVRTGPPKS TDVVRWKITD NVHRSASQQL AQVVPNPKEN
IQFPVSLRLN RLFTDSLSRP DARDTELLRR EVEDNLNEVF KQIPGAQKVK KTIFRTQPNA
GKRQNHTVVD TVLSAPRAAY PDIVNLTEKS VQSGNFGNLK VVPGYYTVAT DRDATGAVEM
QEGVESVDVR VPLFVKDEDD DKKQLRVEAT DVPLGIAEIG RRFVNITIIK DHAKSVLTFL
QPSYVYSRQD KVAKIPVSRE IIEDGHTQVS YRTRDLTAKD QKDYISVDGD LSYQPGETQK
VVPVKLLELG EADSLLSDKQ VKQFVMDLSN PRQGAKLGRY PRTTVTIADQ LEPSVVMFQK
STQNFTTTDK EYSIPVVRTR NQDSLATVQW RTRKASRYDL SGPIKFGPGE TEKNVVIKPY
TYPGAVKPET FQLELYDPSS NAVIGERKTT LVNISEPVDK VQMEFTQSSQ SPGGRLFSPS
NIKPTATGPK SIHLNWDAPH GNPQGYKVKY WIQGDPETDA QVVDCKTTHT ELTNLYPYCD
YEMRVCGYNT LGDGVSSDVV HCQTLEDEPT GPSKKVKIDN PKKRMLLIEN LQPSQTYRYN
VRACNSVGWG PYRDATINLA SQPSRPMSIP IIPDIPIVDA EAGEGYDSFL MYSSDVLRSP
GGRPSVSDEG LRWKHVQLVG EDLDLRKVSW RLPAEIIPQR LSSDTEASDE PPRPGRAQTP
LQDQVMNGKW EQNLLHPGAS GSLMRNLSTS SSSYTQLSPH SQHSSNIRGM GGTTTIETTT
TYLPGNSLSR RQEVTTIGGL RTEEVTLRKR SDNRTYYDND GVRDSIVMVD VPGGFSGSIG
GSGYSRTLTN YNVGSRHRAR THSEDVDDAL QNLDRVLQVD TQITTAMILT LPVLWYLDPR
FTPGVPDTPS RLVFSALGPT ALKVSWQEPH CEREVLGYCV LYQLLNGGEM KRIDVPGNAE
NSVVVQDLLP NHSYIFKVKA QSQEGWGPER EGVITIESAV DPRSPLSPMP GSPFTLSTPS
APGPLVFTAL SPDALQLSWD KPRKPNGDIV GYMVTCEQLH GGGDVRSFQV SGDGAETSLT
VSDLAENVPY KFKVQARTTQ GFGPEREGII TIESQDGGNV SQYSSQSMTR RDVFHLPGEM
STRTNVTHTT FNDPYFKDGM MVTTQHMETG GSITRHVTKE VVTRSVMSGT SGVTKKVEKF
FEA
//
