ID A0A0P7V277_SCLFO Unreviewed; 1382 AA.
AC A0A0P7V277;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Enhancer of mRNA-decapping protein 4 {ECO:0000256|ARBA:ARBA00015762};
GN ORFNames=Z043_115106 {ECO:0000313|EMBL:KPP66397.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP66397.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP66397.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP66397.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the WD repeat EDC4 family.
CC {ECO:0000256|ARBA:ARBA00009639}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP66397.1}.
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DR EMBL; JARO02005673; KPP66397.1; -; Genomic_DNA.
DR STRING; 113540.ENSSFOP00015016785; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR Gene3D; 6.10.140.270; -; 1.
DR Gene3D; 1.10.220.100; conserved c-terminal region of ge- 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045152; EDC4-like.
DR InterPro; IPR049404; EDC4_C.
DR InterPro; IPR044938; EDC4_C_sf.
DR InterPro; IPR032401; EDC4_WD40.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15598; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR PANTHER; PTHR15598:SF5; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR Pfam; PF21289; EDC4_C; 1.
DR Pfam; PF16529; Ge1_WD40; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 108..432
FT /note="Enhancer of mRNA-decapping protein 4 WD40 repeat
FT region"
FT /evidence="ECO:0000259|Pfam:PF16529"
FT REPEAT 285..318
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1252..1372
FT /note="Enhancer of mRNA-decapping protein 4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21289"
FT REGION 607..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 861..918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 923..953
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 876..893
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..918
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1382 AA; 150421 MW; F158B9C118407A28 CRC64;
MASNANMDME DATQQLRDML KLERPTSSDI SSADNQKKSS FNGELNGLFG VGLLSTGDRA
PCADSVNGQD SQIIHLSGDD SSTCVAISSS HVEIVASQES SISSKARGSN KVTIKPVAKY
DWEHKYYYGS LIAVSNSYLA YAIRGAGSYM IRVLCQGTSE RTLLKGFTGA VADLAFAHLD
SSQLACLDEA GNLFIWQLGC HSGKIQEEIL VHVQRPDDTS PSACRRLVWC PFIPEDNDEG
PEDSCQTLAL LHEDRAEVWD LDIIRSNHRC WPVAANDVTE GFITVKGHNG RISEGALSPD
GTVLATASHD GFLKFWQIYI EGQDQPRCLH DWKPHDGRPL SCLLFCDNHK KQDPDVPFWR
FLVTGADQNR ELKMWCTVSW TCLQTIRFSP DPLNSAVLPS MKAVLDLSAE YLILSDVQRK
VLYVMELQQN QERGQAGFTA VSEFLLTHPV LSFGLQDVSR SRLRHTEVLP PEEESESMTV
EGNQGCPVES KEGIQIKLYC VHTKCLQDVQ IWFQPLVRPS SSLFPPTSGS QDHFGPNVDQ
ESGQSELRVL PAMPAPTDFL PPADSVKPTL MTPDAFMTPT ASIPASPGSN VSSLTVVTAM
SCTSAGGRAS EELTQSSKGS LESSALGLGS ASGSASGSPS GSRSGSASSS PCSSAILIPG
LGDQLCPSSS QATVSLGTQN PPLSLDLQAI EPLRVPQASP TRERSPDVIS SASTAMSQDI
PEIASETLQR GLSVAVAGGV VSKGIEPLSS SLHTDSMASA ASALHLLSPQ NHSGSDHGRA
SQELGGTVGG APTDGERLNS TPSLLETALS QEGAAACADS TVSWPAAPDI TRETRNSLAD
CSRDDVKTSA FRRHSYTLVR NSSPDASAEQ SDHEAEVLNL ASSSGNCSSR SSHKLPVKDW
RVSPRSSPKL KRKSKKDDGW VSLETQEELV QLLRSQQREL SELRHNQLEL LQRLTGHIDA
VQSSVLALVE QAVVQQQEQN RILPSRHCME RVLAEGQRRS QELQEELTQQ LVHTLSTAVS
NRLDKVLRDE MKKTIPQAIS KSLEPVTGQL SSTIATKLTA VEAALKENVT KVVKSKNTTD
AIGRAAAEAM QGPIQSAYKE AFQSTVLPVF EKGCQSMFQQ INDSFKQGTH EYIQQLENHL
KNRKQREHDA RDPLVDHLQQ VVDSLQNTTD QLAANVTASV RSEVQHQLHV IVGNLQDSIL
TQVQRIIKGE VSLAMKEQQA VVTSSIMQAM RSAAGTPIPT AHLDYQSQQA SVLQLLQQGQ
INQAFQQALS AADLNLVLYV CETIDSQQVF GQHPCPLIQP VLLSLIQQLS TNLATRTELK
ISYLEDAVMN LDHSDPVTRD HMSSVLTQLR QKLFQFLQME PHGPLSKRAR RLMMMLQGLV
NH
//
