ID A0A0P7V2N2_SCLFO Unreviewed; 2188 AA.
AC A0A0P7V2N2;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Ral GTPase-activating protein subunit alpha-1-like {ECO:0000313|EMBL:KPP75274.1};
DE Flags: Fragment;
GN ORFNames=Z043_105490 {ECO:0000313|EMBL:KPP75274.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP75274.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP75274.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP75274.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP75274.1}.
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DR EMBL; JARO02001504; KPP75274.1; -; Genomic_DNA.
DR STRING; 113540.ENSSFOP00015058825; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR046859; RGPA/RALGAPB_N.
DR InterPro; IPR027107; Tuberin/Ral-act_asu.
DR PANTHER; PTHR10063:SF3; RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-1; 1.
DR PANTHER; PTHR10063; TUBERIN; 1.
DR Pfam; PF20412; RALGAPB_N; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805}.
FT DOMAIN 1902..2110
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT REGION 330..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 835..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..995
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1065..1091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1550..1570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1710..1733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2139..2188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 735..762
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..855
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..995
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1710..1726
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2140..2154
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2165..2188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KPP75274.1"
SQ SEQUENCE 2188 AA; 243844 MW; 864075D9FB3556FB CRC64;
PHGDVKKSTQ KVLDPKKDVL TRLKHLRIVI ENSESVDLKH FFDQNYSHIY YVFFENFVTI
EANLKQKGHK SQREELDSIL FIFEKILQLL PERIQGLWQF HSIGLILKKL LHTGNSLKAL
QTSCQQEQLW IFACLIPGFP PPSSEHGPRT LDGLVNPPLS LQDTQVTPEE ISPLVPPQSG
DKGQEDLTGY FLEALLKYMA KSLEWKCKEN HEKGFAFLFG NFKKYYLPHI FPNFSNETSL
YSPILEIPHM RPKPHYIIVK RDPETNEAIY CTKEMYLNAR VIFIRWLVSF WLEPRATGGT
HIPGMDGDNV PKNIQKAAAG LAAREEGLAR GSEGLDGGGE PEQSHSNTST LTEREPSSSS
LCSVDEEHLT DIEVLRKVFC SSRANVNFIT EVFRQAFLLP MCEAAAMRKV VRVYQEWISQ
EDKPIFMREP EEDRCFHPTA NPGNSADHGL DKEREEEKAL KTPSSGRNPG GVRGPSCKGP
EESVCAGVQA TLQVFITNSS NVFLLEPAND IKFLLEEHVD MCKRVLNIYR SLVMHETMDQ
KTWEQILLVL LRVTECVMKK PPSIMPQGKK NTLSGRLAGA IFQTLIVAWI KGNLNVYISR
ELWDELLQVL SSLTSWEELV TEWSLTMETL TKVLARNLYS LDLGELPLDK LSEQKQKKHK
GKGGVHEGQK LSVDRSFSKG WSRDPPGQVL MRQRSATTAG SPGIEKARSI VRQKTVDLED
PPVATRGPRT RHFSQGEDTP PSEVFSASAE EQPLPRSSST SDIMEPFIAE RVKESVQFHN
PPEHKEGLWK TRLRRLSHFS STGGHTTVSA GLSPLSGDLL PEREVVTRRR LGRGSLMPRS
RSRSQESGCS HWQQQQGALG GVYKSVVHAL SKPKAHASPQ RHSRAAAEAP LRELYSHEDL
GQSLRVASTD ADSSNPNISD LMDEFIQERL RTRNTAGMTR RGSSPGSLEI PKDFPDLLTR
QSAMRPADDP GVPSEWTSPA SASGSDLISS DSQSDSFSAF QEDGCKFENF SFGPEGCSVS
CLEQDGLGVP MQTAEEQELA SLTTLRIDSE TSSLSQLGLS ADTATITGSD SASPAHSPRC
SPSQTPSPAT LNAEPIEHKE LQLDQKLHHS VLQTPDDLET SEFPTEDCSV MAGGTLTGWH
ADVATVMWRR MLGILGDVNA IKDPEIHAQV FDYLCELWQN LAKIRDNLGI SLDNQSSPPP
PALIPPLRIL TPWLFKATML TDRFKQGKLH AYKLICKIMK RRQDVSPNSD FLTHFYNIMH
GGLLHVDQDI VNTIIKHCSP RFFSIGLPGA TMLILDFIVA ASRVTACSSL NAPRVEAQIL
LGSLVCFPNL YEELPALHPT TADMVMTKFR DVKEHIIKHI LSSAREEPSA PARCVALCSL
GLWLCEELMH NTCHPQIKDA LNVLCVTLKF PNKTVALVAS DIVHLLINYV DDLQKFPPDT
PKKIIEVLIA TITHLLPSTE SSPHELDKRL VVSLLLCLLD WVMALPPITL LQPIRTLGPE
KSDKSVLSCI YKVLHGCVYG AQNFSNPKYF PIHLSDLATA DYDPLLPLDS LKEPEPLHSP
DSERSSKLQP VTEVKSRMQH GLISIAARTV ITHLVNHLGH YPMSGGPAML TSQVCENHDN
PYSESPDLSA ELFDSPNLQF FVLNGTTLLS SLQIHAEDNV PGGGMAAGLT SAAACVRLIV
RDISGKYSWD SAVLYGPPQC IQSGLSPSLV VPPHHTQNGP QGTEHELQGE EQQEEAELTL
EEAELEEEGQ ENGEDEAALE FAAPLAKRRC REVVPSWDSM QDGEDALDEM LQYLGVSSPE
CLQRAGTPLN VPAPPPSCVS EKMENDVINA ILKQFTEEKD FSERRDHNLH MCAMQQEQPI
PQKPQSAFYY CRLLLNLLGM NSWEKRSSFH LLKKNEKLLR ELKNLDSRQC RETHKIAVFY
VAEGQEDKHS ILSNTSGSLA YEDFVSGLGW EVDLTTHCGF MGGLQRNRST GLTMPYFATS
TVEVMFHVST RMPPDSDDSL TKKLRHLGND EVHIVWSEHS RDYRRGIIPT EFGDVLIIIY
PMKNHMYSIQ ILKKPEVPFF GPLFDGAIVD EKILPTVVRA TAINASRALK SLIPLYQNFY
EERARYLETI VQHHLEPTTF EDYAAQVFCP APFHQLPSEA GSCPESQQGE SPAAQVDGSD
LASPMSPRAS KSRMSMKLRR SSGSANKT
//
