ID A0A0P7V3B7_SCLFO Unreviewed; 676 AA.
AC A0A0P7V3B7;
DT 20-JAN-2016, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Centrosomal protein of 76 kDa {ECO:0000256|ARBA:ARBA00015706};
GN ORFNames=Z043_105206 {ECO:0000313|EMBL:KPP75539.1};
OS Scleropages formosus (Asian bonytongue) (Osteoglossum formosum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages.
OX NCBI_TaxID=113540 {ECO:0000313|EMBL:KPP75539.1, ECO:0000313|Proteomes:UP000034805};
RN [1] {ECO:0000313|EMBL:KPP75539.1, ECO:0000313|Proteomes:UP000034805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Aro1 {ECO:0000313|EMBL:KPP75539.1};
RA Tan M.H., Gan H.M., Croft L.J., Austin C.M.;
RT "The genome of the Asian arowana (Scleropages formosus).";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Centrosomal protein involved in regulation of centriole
CC duplication. Required to limit centriole duplication to once per cell
CC cycle by preventing centriole reduplication.
CC {ECO:0000256|ARBA:ARBA00024729}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome, centriole {ECO:0000256|ARBA:ARBA00004114}.
CC -!- SIMILARITY: Belongs to the CEP76 family.
CC {ECO:0000256|ARBA:ARBA00005400}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KPP75539.1}.
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DR EMBL; JARO02001418; KPP75539.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P7V3B7; -.
DR STRING; 113540.ENSSFOP00015009939; -.
DR Proteomes; UP000034805; Unassembled WGS sequence.
DR GO; GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 3.10.620.30; -; 1.
DR InterPro; IPR028926; CEP76-C2.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR46436; CENTROSOMAL PROTEIN OF 76 KDA; 1.
DR PANTHER; PTHR46436:SF1; CENTROSOMAL PROTEIN OF 76 KDA; 1.
DR Pfam; PF15627; CEP76-C2; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000034805}.
FT DOMAIN 120..273
FT /note="CEP76 C2"
FT /evidence="ECO:0000259|Pfam:PF15627"
FT REGION 96..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 676 AA; 75266 MW; 81F0F9B430523E38 CRC64;
MEFEVTVIAR EGLVVHGKAE QCDFVDVFRC FVASSHGFST WTVCLTLTEE NCLCNGSCSS
PAHREFAGSN MSLPPEKASE LKQIIHQHLA KEMPQTEAGV SSKPATHFAD KDGISSKKTN
VDPTRRHLYL QVLGGKAFLE HLQEPEPLPG QVCSTFTLYL HFRNQRFRSK PVPCSCEPDL
QEGFLLEVHR GDSSKMLDAT TLLSISDPVQ MVLIRTDTSG ETTLVSSYFL DWRSVLSAPN
GKTSIAVELL GVGSESKVPA GVLNVKLELY PPLAERLSPD VVSTQQSLER KKTAEKERLF
LVYAKQWWRE FLEIRPSHHT KLVKIFAQDE NGVNRPVCSY VHVLRAGRLL ESPRQAARFV
SLLPLEKAPV VGGGVRQEQW CTLLAFLCRN KGDCEDHATL LCSLLLGFGL DAYVCVGTMG
KGVPHAWVMT CGTDGSVTFW ESLTAHRYLH QPINPDDPPL ASQPKPSYPY RTVGCVFNHR
TFLANCQPSD AVELCIFDFQ DQSRWKAMSE EALRAVCAPG STTSLPPLPP LCGPSLDPAA
ASNHLELEMR YLVSEHRKDL SMSTTWDDHL SYLLSAALAA YEQERCTGVS CGNEEFQDAV
RRAVPDGHTF KGFPIHFTHR NARRVFATSL RSPFCEEIVC CRGDHVRLAV RARVFAYPES
ACAVWIMFAC KYRSVL
//
